Troponin as a risk factor for mortality in critically ill patients without acute coronary syndromes

Nonparametric Estimation from Incomplete Observations

1992 • 45,923 citations

Nonparametric Estimation from Incomplete Observations

1958 • 37,219 citations

Definitions for Sepsis and Organ Failure and Guidelines for the Use of Innovative Therapies in Sepsis

1992 • 12,726 citations

Recommendations for Quantitation of the Left Ventricle by Two-Dimensional Echocardiography

1989 • 8,119 citations

A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study

1993 • 6,337 citations

A New Simplified Acute Physiology Score (SAPS II) Based on a European/North American Multicenter Study

1993 • 5,263 citations

Myocardial infarction redefined—a consensus document of The Joint European Society of Cardiology/American College of Cardiology committee for the redefinition of myocardial infarction

2000 • 4,786 citations

ACC/AHA Guidelines for the Management of Patients With Unstable Angina and Non–ST-Segment Elevation Myocardial Infarction: Executive Summary and Recommendations

2000 • 4,662 citations

Pathogenetic Mechanisms of Septic Shock

1993 • 1,577 citations

The Pathogenesis of Vasodilatory Shock

2001 • 1,089 citations

Tumor necrosis factor alpha and interleukin 1beta are responsible for in vitro myocardial cell depression induced by human septic shock serum.

1996 • 770 citations

Independent Prognostic Value of Cardiac Troponin T in Patients With Confirmed Pulmonary Embolism

2000 • 513 citations

The prognostic value of troponin in patients with non-ST elevation acute coronary syndromes: a meta-analysis

2001 • 396 citations

Elevation of troponin I in sepsis and septic shock

2001 • 369 citations

Cardiac Troponins I and T Are Biological Markers of Left Ventricular Dysfunction in Septic Shock

2000 • 324 citations

Dobutamine stress echocardiography for detection and assessment of coronary artery disease

1992 • 295 citations

Lenercept (p55 tumor necrosis factor receptor fusion protein) in severe sepsis and early septic shock: A randomized, double-blind, placebo-controlled, multicenter phase III trial with 1,342 patients

2001 • 289 citations

Randomized, placebo-controlled trial of the anti-tumor necrosis factor antibody fragment afelimomab in hyperinflammatory response during severe sepsis: The RAMSES Study

2001 • 251 citations

Myocardial injury in critically ill patients. A frequently unrecognized complication

1996 • 251 citations

Cardiac Troponin T Predicts Mortality in Patients With End-Stage Renal Disease

2000 • 246 citations

Serum Cardiac Troponin T as a Prognostic Marker in Early Sepsis

1998 • 238 citations

Myocardial necrosis in ICU patients with acute non-cardiac disease: a prospective study

2000 • 232 citations

Myocardial cell injury in septic shock

1999 • 231 citations

Relation between troponin T concentration and mortality in patients presenting with an acute stroke: observational study

2000 • 219 citations

Myocardial Injury in Critically Ill Patients

1995 • 205 citations

Release of cardiac troponin in acute coronary syndromes: ischemia or necrosis?

1999 • 170 citations

Early enzyme release from myocardial cells is not due to irreversible cell damage*

1984 • 155 citations

Effects of granulocyte colony-stimulating factor on plasma cytokine and cytokine receptor levels and on the in vivo host response to endotoxin in healthy men

1996 • 86 citations

Combination immunotherapy with soluble tumor necrosis factor receptors plus interleukin 1 receptor antagonist decreases sepsis mortality

2001 • 76 citations