Resolution of Three Nonproliferative Immature Splenic B Cell Subsets Reveals Multiple Selection Points During Peripheral B Cell Maturation

Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice

1988 • 1,562 citations

Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes

1989 • 1,015 citations

B Cell Development in the Spleen Takes Place in Discrete Steps and Is Determined by the Quality of B Cell Receptor–Derived Signals

1999 • 843 citations

Defective B cell development and function in Btk-deficient mice

1995 • 729 citations

Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire

1994 • 541 citations

Elimination of self-reactive B lymphocytes proceeds in two stages: Arrested development and cell death

1993 • 514 citations

Characterization of the B Lymphocyte Populations in Lyn-Deficient Mice and the Role of Lyn in Signal Initiation and Down-Regulation

1997 • 451 citations

Peripheral B cell maturation. II. Heat-stable antigen(hi) splenic B cells are an immature developmental intermediate in the production of long-lived marrow-derived B cells.

1993 • 413 citations

Identification of the Earliest B Lineage Stage in Mouse Bone Marrow

1996 • 395 citations

Continued RAG expression in late stages of B cell development and no apparent re-induction after immunizion

1999 • 372 citations

Transitional B cells are the target of negative selection in the B cell compartment.

1995 • 352 citations

Self-Tolerance Checkpoints in B Lymphocyte Development

1995 • 329 citations

Impaired expansion of mouse B cell progenitors lacking Btk

1995 • 314 citations

Characterization of immature B cells by a novel monoclonal antibody, by turnover and by mitogen reactivity

1998 • 267 citations

Peripheral B cell maturation. I. Immature peripheral B cells in adults are heat-stable antigenhi and exhibit unique signaling characteristics.

1992 • 246 citations

Engagement of the antigen-receptor on immature murine B lymphocytes results in death by apoptosis.

1995 • 216 citations

Negative Selection of Immature B Cells by Receptor Editing or Deletion Is Determined by Site of Antigen Encounter

1999 • 209 citations

Syk Tyrosine Kinase Is Required for the Positive Selection of Immature B Cells into the Recirculating B Cell Pool

1997 • 163 citations

A B-cell receptor-specific selection step governs immature to mature B cell differentiation

2000 • 159 citations

The Molecular Characterization of the Fetal Stem Cell Marker AA4

1999 • 159 citations

B-cell subpopulations identified by two-colour fluorescence analysis

1982 • 135 citations

Commitment to the B Lymphoid Lineage Occurs before DH-JH Recombination

1999 • 135 citations

Demonstration of B-cell maturation in X-linked immunodeficient mice by simultaneous three-colour immunofluorescence

1983 • 133 citations

Signaling through surface IgM in tolerance-susceptible immature murine B lymphocytes. Developmentally regulated differences in transmembrane signaling in splenic B cells from adult and neonatal mice.

1991 • 111 citations

Comparative in vitro analysis of proliferation, Ig secretion, and Ig class switching by murine marginal zone and follicular B cells.

1993 • 86 citations

Independent and Opposing Roles For Btk and Lyn in B and Myeloid Signaling Pathways

1998 • 74 citations

Differential expression of CD22 (Lyb8) on murine B cells

1996 • 72 citations

Mutations Affecting Either Generation or Survival of Cells Influence the Pool Size of Mature B Cells

1999 • 57 citations

The Transition from Immature to Mature B Cells

1999 • 12 citations