Crystal Structure of an Ecotin−Collagenase Complex Suggests a Model for Recognition and Cleavage of the Collagen Triple Helix

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

A graphics model building and refinement system for macromolecules

1978 • 1,858 citations

Crystal and Molecular Structure of a Collagen-Like Peptide at 1.9 Å Resolution

1994 • 1,043 citations

Molecular Structure of Collagen

1963 • 715 citations

The geometry of the reactive site and of the peptide groups in trypsin, trypsinogen and its complexes with inhibitors

1983 • 580 citations

Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor

1974 • 548 citations

Macroscopic models of aqueous solutions: biological and chemical applications

1993 • 520 citations

Model bias in macromolecular crystal structures

1992 • 397 citations

The X-ray crystal structure of the catalytic domain of human neutrophil collagenase inhibited by a substrate analogue reveals the essentials for catalysis and specificity.

1994 • 342 citations

Chain conformation in the collagen molecule

1979 • 315 citations

Exploring structural homology of proteins

1976 • 289 citations

1.56 Å structure of mature truncated human fibroblast collagenase

1994 • 183 citations

Interactive program for visualization and modelling of proteins, nucleic acids and small molecules

1986 • 163 citations

Structure of Thermolysin

1972 • 163 citations

Cloning and functional expression of a cDNA encoding the catalytic subunit of bovine enterokinase.

1993 • 114 citations

Role of zinc-binding- and hemopexin domain-encoded sequences in the substrate specificity of collagenase and stromelysin-2 as revealed by chimeric proteins.

1993 • 109 citations

Hypothesis for a Neuronal Mechanism involved in Memory

1972 • 86 citations

Macromolecular chelation as an improved mechanism of protease inhibition: structure of the ecotin-trypsin complex.

1994 • 68 citations

Direct phase determination for the molecular envelope of tryptophanyl-tRNA synthetase from Bacillus stearothermophilus by X-ray contrast variation

1990 • 63 citations

Molecular cloning of a cDNA that encodes a serine protease with chymotryptic and collagenolytic activities in the hepatopancreas of the shrimp Penaeus vanameii (Crustacea, Decapoda)

1992 • 59 citations

The sequence and reactive site of ecotin. A general inhibitor of pancreatic serine proteases from Escherichia coli.

1991 • 57 citations

Complete amino acid sequence of the collagenase from the insect Hypoderma lineatum.

1987 • 44 citations