Loss of stearoyl–CoA desaturase-1 function protects mice against adiposity

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Role for Stearoyl-CoA Desaturase-1 in Leptin-Mediated Weight Loss

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Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy

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Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol

1999 • 737 citations

Lipodystrophy in the fld mouse results from mutation of a new gene encoding a nuclear protein, lipin

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Leptin-specific patterns of gene expression in white adipose tissue

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The Biosynthesis of Hepatic Cholesterol Esters and Triglycerides Is Impaired in Mice with a Disruption of the Gene for Stearoyl-CoA Desaturase 1

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Differentiation-induced Gene Expression in 3T3-L1 Preadipocytes

1989 • 373 citations

Differentiation-induced gene expression in 3T3-L1 preadipocytes. Characterization of a differentially expressed gene encoding stearoyl-CoA desaturase.

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The regulation of stearoyl-CoA desaturase (SCD)

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Evidence for an increase in transcription of specific mRNAs during differentiation of 3T3-L1 preadipocytes.

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A lipogenic diet in mice with a disruption of the stearoyl-CoA desaturase 1 gene reveals a stringent requirement of endogenous monounsaturated fatty acids for triglyceride synthesis

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Targeted Disruption of Stearoyl-CoA Desaturase1 Gene in Mice Causes Atrophy of Sebaceous and Meibomian Glands and Depletion of Wax Esters in the Eyelid

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Human stearoyl-CoA desaturase: alternative transcripts generated from a single gene by usage of tandem polyadenylation sites

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Dietary Fats, Membrane Phospholipids and Obesity

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Scd3—A Novel Gene of the Stearoyl-CoA Desaturase Family with Restricted Expression in Skin

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Increased insulin sensitivity despite lipodystrophy in Crebbp heterozygous mice

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Genetic obesity unmasks nonlinear interactions between murine type 2 diabetes susceptibility loci.

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Mutation of Host Δ9 Fatty Acid Desaturase Inhibits Brome Mosaic Virus RNA Replication between Template Recognition and RNA Synthesis

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Partial characterization of a cDNA for human stearoyl‐CoA desaturase and changes in its mRNA expression in some normal and malignant tissues

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Oleoyl-CoA Is the Major de NovoProduct of Stearoyl-CoA Desaturase 1 Gene Isoform and Substrate for the Biosynthesis of the Harderian Gland 1-Alkyl-2,3-diacylglycerol

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Adipose tissue stearoyl-CoA desaturase mRNA is increased by obesity and decreased by polyunsaturated fatty acids

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Structure and Regulation of Rat Liver Microsomal Stearoyl-CoA Desaturase Gene

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Coordinate Regulation of Lipogenesis, the Assembly and Secretion of Apolipoprotein B-containing Lipoproteins by Sterol Response Element Binding Protein 1

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The 70-kDa Peroxisomal Membrane Protein (PMP70), an ATP-Binding Cassette Transporter

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Desaturation of stearic acid by liver and adipose tissue from obese-hyperglycaemic mice (ob/ob)

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Manipulation of body fat composition with sterculic acid can inhibit mammary carcinomas in vivo

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Growth hormone or insulin-like growth factor I increases fat oxidation and decreases protein oxidation without altering energy expenditure in parenterally fed rats

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