Metabolism and Function of myo-Inositol and Inositol Phospholipids

RECEPTORS AND PHOSPHOINOSITIDE-GENERATED SECOND MESSENGERS

1985 • 722 citations

Diglyceride lipase: a pathway for arachidonate release from human platelets.

1979 • 696 citations

The Enzymatic Synthesis of Inositol Monophosphatide

1960 • 436 citations

Rapid mobilization of Ca2+ from rat insulinoma microsomes by inositol-1,4,5-trisphosphate

1984 • 410 citations

d-Myoinositol 1-Phosphate as Product of Cyclization of Glucose 6-Phosphate and Substrate for a Specific Phosphatase in Rat Testis

1967 • 252 citations

Structure of "phytic acids"

1969 • 209 citations

Positional specificity of saturated and unsaturated fatty acids in phosphatidic acid from rat liver

1969 • 179 citations

Action of Sorbinil in Diabetic Peripheral Nerve: Relationship of Polyol (Sorbitol) Pathway Inhibition to a myo-Inositol-mediated Defect in Sodium-Potassium ATPase Activity

1984 • 178 citations

Oncogenes, ions, and phospholipids

1985 • 171 citations

Identification of covalently bound inositol in the hydrophobic membrane-anchoring domain of Torpedo acetylcholinesterase

1985 • 150 citations

Free and lipid myo-inositol in tissues from rats with acute and less severe streptozotocin-induced diabetes

1977 • 147 citations

Molecular species of mono-, di-, and triphosphoinositides of bovine brain

1970 • 140 citations

Regional distribution of polyphosphoinositides in rat brain

1971 • 110 citations

Free and lipid inositol, sorbitol and sugars in sciatic nerve obtained post-mortem from diabetic patients and control subjects

1983 • 110 citations

The Biosynthesis of Free and Phosphatide Myo-inositol from Glucose by Mammalian Tissue Slices

1963 • 103 citations

Inositol cyclic phosphates are produced by cleavage of phosphatidylphosphoinositols (polyphosphoinositides) with purified sheep seminal vesicle phospholipase C enzymes.

1985 • 103 citations

CDP-diglyceride:inositol transferase from rat liver. Purification and properties.

1977 • 98 citations

Phosphatidylinositol as the endogenous activator of the (Na+ + K+)-ATPase in microsomes of rabbit kidney

1978 • 98 citations

Inositol lipids, phosphatidate and diacylglycerol share stearoylarachidonoylglycerol as a common backbone in thrombin-stimulated human platelets

1984 • 93 citations

THE DISTRIBUTION OF CALCIUM‐DEPENDENT PHOSPHATIDYLINOSITOL‐SPECIFIC PHOSPHODIESTERASE IN RAT BRAIN

1978 • 90 citations

Metabolism of 14C-Phytate in Rats: Effect of Low and High Dietary Calcium Intakes

1980 • 85 citations

Selective Effects of Myo-inositol Administration on Sciatic and Tibial Motor Nerve Conduction Parameters in the Streptozocin-Diabetic Rat

1982 • 81 citations

Soluble and particulate forms of phosphoinositide phosphodiesterase in ox brain

1972 • 71 citations

Phosphatidic acid releases calcium from a platelet membrane fraction in vitro

1978 • 67 citations

myo-Inositol oxygenase from hog kidney. I. Purification and characterization of the oxygenase and of an enzyme complex containing the oxygenase and D-glucuronate reductase.

1981 • 62 citations

Biosynthesis of inositol in rat testis homogenate

1963 • 61 citations

Studies on the developmental pattern of the enzymes converting glucose 6-phosphate to myo-inositol in the rat

1974 • 59 citations

Specific formation of arachidonoyl phosphatidylinositol from 1‐acyl‐sn‐glycero‐3‐phosphorylinositol in rat liver

1976 • 58 citations

The metabolism of myo-inositol by the human kidney.

1979 • 55 citations

Reproductive Tract as Site of Synthesis and Secretion of Inositol in the Male Rat

1964 • 51 citations

Accumulation of the inositol phosphates in thrombin-stimulated, washed rabbit platelets in the presence of lithium

1984 • 50 citations

The phosphatidate-phosphoinositide cycle: An intracellular messenger system in the action of hormones and neurotransmitters

1983 • 46 citations

Localization of enzymes involve in polyphosphoinositide metabolism on the cytoplasmic surface of the human erythrocyte membrane

1975 • 46 citations

Studies on Avian Erythrocyte Metabolism

1977 • 45 citations

Inositol Deficiency: an Intestinal Lipodystrophy in the Gerbil

1973 • 45 citations

Accumulation of acidic phospholipids in a case of hyperlipidemia with hepatosplenomegaly

1970 • 43 citations

Effect of experimental diabetes and insulin on phosphatidylinositol synthesis in rat sciatic nerve

1979 • 42 citations

An alteration in internodal myelin membrane structure in large sciatic nerve fibres in rats with acute streptozotocin diabetes and impaired nerve conduction velocity

1978 • 36 citations

Inositol accumulation by brain slices in vitro

1976 • 35 citations

myo-Inositol Metabolism during Lactation and Development in the Rat. The Prevention of Lactation-Induced Fatty Liver by Dietary myo-Inositol

1976 • 35 citations

Synthesis of CDP-diglyceride from phosphatidylinositol and CMP

1977 • 34 citations

Effect of Dietary Fat on Hepatic Metabolism of 14C-Oleic Acid and Very Low Density Lipoprotein Triglyceride in the Gerbil

1976 • 32 citations

Further evidence for the interconversion of monophosphoinositides in vivo

1972 • 32 citations

The Distribution of Free Myo-Inositol in Fluids, Spermatozoa, and Tissues of the Bull Genital Tract and Observations on its Uptake by the Rabbit Epididymis

1973 • 31 citations

Altered phospholipid composition of plasma membranes from thrombin-stimulated human platelets

1985 • 30 citations

The deacylation of phosphatidylinositol by rat brain preparations

1979 • 27 citations

Inositol Deficiency in Gerbils: Dietary Effects on the INtestinal Lipodystrophy

1973 • 27 citations

Myo-inositol transport in slices of rat kidney cortex

1969 • 27 citations

Membrane lipids of hepatic tissue. II. Phospholipids from subcellular fractions of liver and hepatoma 7288CTC.

1983 • 26 citations

Altered turnover of polyphosphoinositides in the erythrocyte membrane of the spontaneously hypertensive rat.

1983 • 26 citations

Prostatic Secretion as the Source of Myo-Inositol in Human Seminal Fluid

1973 • 25 citations

Inositol Requirement of the Gerbil

1974 • 25 citations

Possible involvement of 1-acyl-glycerophosphorylinositol acyltransferase in arachidonate enrichment of phosphatidylinositol in human platelets

1983 • 25 citations

Enhanced turnover of arachidonic acid-containing species of phosphatidylinositol and phosphatidic acid of concanavalin astimulated lymphocytes

1984 • 24 citations

Untersuchungen zur intestinalen Hydrolyse von Inositphosphorsäureester und zur Absorption von Phytinphosphor beim Schwein

1972 • 24 citations

SUITABILITY OF DIFFERENT MOLECULAR SPECIES OF 1,2‐DIACYLGLYCEROLS AS SUBSTRATES FOR DIACYLGLYCEROL KINASE IN RAT BRAIN MICROSOMES

1978 • 23 citations

Early effect of myo-inositol deficiency on fatty acid synthetic enzymes of rat liver

1982 • 23 citations

The Influence of Dietary Inositol on Glyceride Composition and Synthesis in Livers of Rats Fed Different Fats

1976 • 22 citations

Characterization of the individual phospholipids and their fatty acids in serum and high-density lipoprotein of the renal patient on long-term maintenance hemodialysis.

1983 • 22 citations

myo-Inositol binding and transport in brush border membranes of rat kidney

1977 • 20 citations

Stereospecificity of L-myo-inositol-1-phosphate synthase for nicotinamide adenine dinucleotide

1981 • 18 citations

Characterization of the Lactation-Dependent Fatty Liver in myo-Inositol Deficient Rats

1977 • 18 citations

myo-Inositol transport in plasma membrane of rat kidney

1974 • 15 citations

Role of cytidine triphosphate and cytidine diphosphate in promoting inositol entry into microsomal phosphatidylinositol

1975 • 15 citations

Synthesis of molecular classes of cytidine diphosphate diglyceride by rat liver in vivo and in vitro

1977 • 13 citations

The effect of massive doses of myo-inositol on hepatic phospholipid metabolism.

1969 • 12 citations

Chymotrypsinogen · inositol phosphatide complexes and the transport of digestive enzyme across membranes

1978 • 9 citations

STUDIES ON MYOINOSITOL

1974 • 9 citations

The Relative Response of Hepatic Lipids in the Rat to Graded Levels of Dietary Myo-Inositol and Other Lipotropes

1980 • 9 citations

EFFECT OF DIETARY PROTEIN ON THE BIOSYNTHESIS OF INOSITOL IN RAT TESTES

1975 • 8 citations

Rapid screening test for detection of elevated MYO-Inositol levels in human blood serum

1974 • 7 citations

The 5-hydroxyl of myo-inositol is essential for uptake into HSDM1C1 mouse fibrosarcoma cells

1985 • 4 citations

The Effect of Carbohydrate and Inositol on the Growth of Rats

1972 • 2 citations