Neurotrophins and nerve injury in the adult

Functions of the neurotrophins during nervous system development: What the knockouts are teaching us

1994 • 1,431 citations

The trk proto-oncogene encodes a receptor for nerve growth factor

1991 • 1,396 citations

trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3

1991 • 1,078 citations

Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF

1991 • 1,049 citations

p75 and Trk: A two-receptor system

1995 • 861 citations

The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor

1991 • 819 citations

Enhanced synthesis of brain-derived neurotrophic factor in the lesioned peripheral nerve: different mechanisms are responsible for the regulation of BDNF and NGF mRNA.

1992 • 719 citations

Differential regulation of mRNA encoding nerve growth factor and its receptor in rat sciatic nerve during development, degeneration, and regeneration: role of macrophages.

1987 • 711 citations

Differential expression of mRNAs for neurotrophins and their receptors after axotomy of the sciatic nerve.

1993 • 685 citations

Expression and coexpression of Trk receptors in subpopulations of adult primary sensory neurons projecting to identified peripheral targets

1994 • 581 citations

Nerve growth factor in sympathetic ganglia and corresponding target organs of the rat: correlation with density of sympathetic innervation.

1983 • 564 citations

Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells

1993 • 525 citations

Differential influence of nerve growth factor on neuropeptide expression in vivo: a novel role in peptide suppression in adult sensory neurons

1995 • 382 citations

Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration.

1992 • 365 citations

Colocalization of NGF binding sites, trk mRNA, and low-affinity NGF receptor mRNA in primary sensory neurons: responses to injury and infusion of NGF

1992 • 346 citations

Nerve growth factor protects adult sensory neurons from cell death and atrophy caused by nerve injury

1987 • 316 citations

Regulation of ciliary neurotrophic factor expression in myelin-related Schwann cells in vivo

1992 • 309 citations

Neurotrophin receptor mRNA expression defines distinct populations of neurons in rat dorsal root ganglia

1995 • 307 citations

Induction of interleukin-6 in axotomized sensory neurons

1995 • 273 citations

Nerve growth factor counteracts the neurophysiological and neurochemical effects of chronic sciatic nerve section

1985 • 268 citations

Retrograde axonal transport of LIF is increased by peripheral nerve injury: Correlation with increased LIF expression in distal nerve

1994 • 268 citations

Evidence that endogenous beta nerve growth factor is responsible for the collateral sprouting, but not the regeneration, of nociceptive axons in adult rats.

1987 • 265 citations

Neuronal and nonneuronal expression of neurotrophins and their receptors in sensory and sympathetic ganglia suggest new intercellular trophic interactions

1995 • 247 citations

Retrograde axonal transport of ciliary neurotrophic factor is increased by peripheral nerve injury

1993 • 230 citations

Differential role of the low affinity neurotrophin receptor (p75) in retrograde axonal transport of the neurotrophins

1995 • 217 citations

Sensory nerves in adult rats regenerate and restore sensory function to the skin independently of endogenous NGF

1992 • 191 citations

Expression of mRNA for neurotrophic factors and their receptors in the rat dorsal root ganglion and sciatic nerve following nerve injury

1993 • 180 citations

Biological importance of the retrograde axonal transport of nerve growth factor in sensory neurons.

1981 • 180 citations

Nerve growth factor receptors on normal and injured sensory neurons

1989 • 165 citations

Histochemical characterization of sensory neurons with high-affinity receptors for nerve growth factor

1989 • 165 citations

NGF receptor-mediated reduction in axonal NGF uptake and retrograde transport following sciatic nerve injury and during regeneration

1991 • 161 citations

Expression of mRNAs for neurotrophin receptors in the dorsal root ganglion and spinal cord during development and following peripheral or central axotomy

1993 • 155 citations

Role of nerve growth factor in the adult dorsal root ganglia neuron and its response to injury

1984 • 152 citations

Correlation between GAP43 and nerve growth factor receptors in rat sensory neurons

1990 • 140 citations

Influence of nerve growth factor on neurofilament gene expression in mature primary sensory neurons

1990 • 123 citations

Increased NGF mRNA expression in denervated rat skin

1993 • 111 citations

Axonal blockade induces the expression of vasoactive intestinal polypeptide and galanin in rat dorsal root ganglion neurons

1992 • 102 citations

Neuropeptide expression by newborn and adult rat sensory neurons in culture: Effects of nerve growth factor and other neurotrophic factors

1994 • 101 citations

The influence of regeneration and nerve growth factor on the neuronal cell body reaction to injury

1989 • 78 citations

Regulation of the transcription factor c-JUN by nerve growth factor in adult sensory neurons

1993 • 77 citations

Alterations in the structure, function, and chemistry of C fibers following local application of vinblastine to the sciatic nerve of the rat

1984 • 67 citations

Transganglionic regulation of central terminals of dorsal root ganglion cells by nerve growth factor (NGF)

1985 • 62 citations

Cooperative regulation of calcitonin gene-related peptide levels in rat sensory neurons via their central and peripheral processes

1992 • 62 citations

Inflammation and axonal regeneration

1994 • 58 citations

Decreased synthesis of ciliary neurotrophic factor in degenerating peripheral nerves

1992 • 49 citations

REVIEW ■ : Neurotrophic Factors and the Specification of Neural Function

1995 • 42 citations

Vasoactive intestinal polypeptide in dorsal root terminals of the rat spinal cord is regulated by the axoplasmic transport in the peripheral nerve

1991 • 18 citations