Therapeutic lymphangiogenesis with human recombinant VEGF‐C

Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis

2001 • 1,707 citations

A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases.

1996 • 1,670 citations

Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development.

1995 • 1,421 citations

Hyperplasia of Lymphatic Vessels in VEGF-C Transgenic Mice

1997 • 1,280 citations

Constitutive Expression of phVEGF ₁₆₅ After Intramuscular Gene Transfer Promotes Collateral Vessel Development in Patients With Critical Limb Ischemia

1998 • 1,109 citations

Clinical applications of angiogenic growth factors and their inhibitors

1999 • 1,017 citations

Cardiovascular Failure in Mouse Embryos Deficient in VEGF Receptor-3

1998 • 876 citations

Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, Angiopoietins, and ephrins in vascular development

1999 • 795 citations

Proteolytic processing regulates receptor specificity and activity of VEGF-C

1997 • 773 citations

Regulation of angiogenesis via vascular endothelial growth factor receptors.

2000 • 749 citations

Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice

2001 • 652 citations

Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema

2000 • 625 citations

A model for gene therapy of human hereditary lymphedema

2001 • 585 citations

VEGF and VEGF-C: Specific Induction of Angiogenesis and Lymphangiogenesis in the Differentiated Avian Chorioallantoic Membrane

1997 • 501 citations

Incidence of breast carcinoma-related lymphedema

1998 • 467 citations

Lymphedema

2001 • 431 citations

Lymphedema: classification, diagnosis and therapy

1998 • 416 citations

A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases.

1996 • 416 citations

Vascular endothelial growth factor-related protein: a ligand and specific activator of the tyrosine kinase receptor Flt4.

1996 • 406 citations

VEGF‐C and VEGF‐D expression in neuroendocrine cells and their receptor, VEGFR‐3, in fenestrated blood vessels in human tissues

2000 • 343 citations

Current Therapy in Vascular Surgery

1988 • 281 citations

Monoclonal antibody PAL-E specific for endothelium.

1985 • 251 citations

The pathophysiology of lymphedema

1998 • 240 citations

Structure, Function, and Molecular Control of the Skin Lymphatic System

2000 • 232 citations

Direct and indirect methods for the quantification of leg volume: comparison between water displacement volumetry, the disk model method and the frustum sign model method, using the correlation coefficient and the limits of agreement

1993 • 203 citations

Markers for the lymphatic endothelium: In search of the holy grail?

2001 • 196 citations

Factors that Influence the Incidence of Brachial Oedema After Treatment of Breast Cancer

1992 • 175 citations

Adenoviral VEGF‐C overexpression induces blood vessel enlargement, tortuosity, and leakiness but no sprouting angiogenesis in the skin or mucous membranes

2002 • 173 citations

Workgroup III

1998 • 161 citations

A review of measures of lymphedema

1998 • 120 citations

Quantitative radionuclide lymphoscintigraphy predicts outcome of manual lymphatic therapy in breast cancer-related lymphedema of the upper extremity

2002 • 102 citations

Idiopathic Lymphedema

1962 • 70 citations

An Experimental Model for Chronic Lymphedema

1990 • 66 citations

Imaging techniques in the management and prevention of posttherapeutic upper limb edemas

1998 • 62 citations

Angiogenesis and Vasculogenesis in Treatment of Cardiovascular Disease

1998 • 60 citations

Pathology of lymphedema

1995 • 57 citations

Angiogenesis in wound healing and tumor metastasis.

1993 • 56 citations

Macrophage and tissue changes in the developmental phases of secondary lymphoedema and during conservative therapy with benzopyrone.

1990 • 52 citations

Phenotype of Normal Cutaneous Microvasculature

1996 • 50 citations

Lymphoedema, macrophages and benzopyrones.

1980 • 48 citations

Refinement of a rodent model of peripheral lymphedema.

1999 • 45 citations

The interstitium, the connective tissue environment of the lymphatic, and angiogenesis in human skin

1995 • 38 citations

Experimental lymphedema in dogs.

1968 • 34 citations

An experimental model for lymphedema in rabbit ear

1983 • 33 citations

Creation of Distal Canine Limb Lymphedema

1989 • 19 citations

[Treatment of postoperative lymphedema of the upper limb].

1991 • 6 citations

Alterations in lymphatic vessels in the course of chronic experimental lymphedema.

1970 • 5 citations