Pregnancy Increases Ovine Uterine Artery Endothelial Cyclooxygenase-1 Expression*

Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing.

1991 • 1,734 citations

Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic.

1994 • 1,322 citations

Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal anti-inflammatory drugs.

1993 • 1,270 citations

Identification and isolation of endothelial cells based on their increased uptake of acetylated-low density lipoprotein.

1984 • 1,249 citations

Prostaglandin endoperoxide synthase: regulation of enzyme expression

1991 • 642 citations

Mitogen‐inducible prostaglandin G/H synthase: A new target for nonsteroidal antiinflammatory drugs

1992 • 313 citations

Purification and characterization of a novel, distinct isoform of prostaglandin endoperoxide synthase induced by human chorionic gonadotropin in granulosa cells of rat preovulatory follicles.

1992 • 312 citations

Prostacyclin production during pregnancy: Comparison of production during normal pregnancy and pregnancy complicated by hypertension

1982 • 234 citations

Lipopolysaccharide priming of alveolar macrophages for enhanced synthesis of prostanoids involves induction of a novel prostaglandin H synthase.

1992 • 212 citations

Distribution of cardiac output in ovine pregnancy

1977 • 175 citations

Endothelial vasodilator production by uterine and systemic arteries. II. Pregnancy effects on NO synthase expression

1997 • 170 citations

Nitric oxide-mediated cyclooxygenase activation. A key event in the antiplatelet effects of nitrovasodilators.

1996 • 169 citations

Stimulation of prostacyclin biosynthetic activity by estradiol in rat aortic smooth muscle cells in culture

1980 • 163 citations

Effect of Prostaglandin Synthetase Inhibitors on Pressor Response to Angiotensin II in Human Pregnancy*

1978 • 156 citations

Identification of a cyclooxygenase-related gene and its potential role in prostaglandin formation

1989 • 154 citations

Expression of Cyclooxygenase-1 and -2 in Ovine Endometrium During the Estrous Cycle and Early Pregnancy¹

1997 • 154 citations

Concentrations of prostaglandin endoperoxide synthase and prostaglandin I2 synthase in the endothelium and smooth muscle of bovine aorta.

1983 • 148 citations

Stimulation of prostaglandin cyclooxygenase and prostacyclin synthetase activities by estradiol in rat aortic smooth muscle cells

1980 • 125 citations

Quantification of mRNA Using Competitive RTPCR with Standard-Curve Methodology

1996 • 117 citations

Conjugated and Unconjugated Estrogens in Fetal and Maternal Fluids of the Pregnant Ewe: A Possible Role for Estrone Sulfate during Early Pregnancy1

1978 • 111 citations

Prostacyclin synthesis in ovine pulmonary artery is developmentally regulated by changes in cyclooxygenase-1 gene expression.

1994 • 110 citations

Effect of angiotensin II on uterine and systemic vasculature in pregnant sheep.

1981 • 105 citations

Phorbol Ester and Epidermal Growth Factor Enhance the Expression of Two Inducible Prostaglandin H Synthase Genes in Rat Tracheal Epithelial Cells

1993 • 96 citations

In vitro prostacyclin production by ovine uterine and systemic arteries. Effects of angiotensin II.

1985 • 93 citations

Protein kinase C in uterine and systemic arteries during ovarian cycle and pregnancy

1991 • 76 citations

Shear Stress-Induced Release of PGE2and PGI2by Vascular Smooth Muscle Cells

1996 • 72 citations

Inhibitors of protein and RNA synthesis cause a rapid block in prostaglandin production at the prostaglandin synthase step.

1986 • 70 citations

Continuous RT-PCR using AMV-RT and Taq DNA polymerase: characterization and comparison to uncoupled procedures.

1995 • 61 citations

Angiotensin II metabolic clearance rate and pressor responses in nonpregnant and pregnant women

1994 • 60 citations

Uterine prostaglandin production in ovine pregnancy: effects of angiotensin II and indomethacin

1992 • 59 citations

Effects of indomethacin on sheep uteroplacental circulations and sensitivity to angiotensin II

1978 • 58 citations

Expression of Basic Fibroblast Growth Factor, Endothelial Mitogenic Activity, and Angiotensin II Type-1 Receptors in the Ovine Placenta during the Third Trimester of Pregnancy1

1997 • 56 citations

Regulation of COX-2 gene expression in rat uterus in vivo and in vitro

1996 • 56 citations

Pregnancy Induces an Increase in Angiotensin II Type-1 Receptor Expression in Uterine But Not Systemic Artery Endothelium¹

1997 • 54 citations

Uteroplacental production of eicosanoids in ovine pregnancy

1990 • 50 citations

Calcium modulation of endothelium-derived prostacyclin production in ovine pregnancy.

1993 • 39 citations

Epidermal Growth Factor in Urine of Nonpregnant Women and Pregnant Women Throughout Pregnancy and At Delivery*

1988 • 33 citations

Uterine and umbilical flow velocity waveforms in normotensive and hypertensive subjects during the angiotensin II sensitivity test

1992 • 32 citations

Regulation of platelet-derived growth factor isoform-mediated expression of prostaglandin G/H synthase in mesangial cells

1996 • 24 citations

Induction of cyclooxygenase protein and stimulation of prostaglandin E2 release by epidermal growth factor in cultured guinea pig gastric mucous cells

1995 • 22 citations

Angiotensin II and alpha-agonist. III. In vitro fetal-maternal placental prostaglandins

1991 • 19 citations

A General Method for Single-Stranded DNA Probe Generation

1997 • 16 citations