Ligand binding to thromboxane receptors on human platelets: correlation with biological activity

Advanced Organic Chemistry: Reactions, Mechanisms, and Structure

1977 • 4,066 citations

Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides.

1975 • 3,075 citations

Prostaglandin Endoperoxides. Novel Transformations of Arachidonic Acid in Human Platelets

1974 • 1,410 citations

Identification of an enzyme in platelet microsomes which generates thromboxane A2 from prostaglandin endoperoxides

1976 • 533 citations

Prostaglandin Endoperoxides. A New Concept Concerning the Mode of Action and Release of Prostaglandins

1974 • 495 citations

Thromboxanes: Selective Biosynthesis and Distinct Biological Properties

1976 • 390 citations

A Theoretical Study of the Binding of Small Molecules to a Polymerizing Protein System. A Model for Allosteric Effects^*

1967 • 214 citations

The synthesis of prostaglandin endoperoxide analogs

1975 • 198 citations

Prostaglandin Endoperoxides IX. Characterization of Rabbit Aorta Contracting Substance (RCS) from Guinea Pig Lung and Human Platelets

1975 • 179 citations

An endoperoxide aggregator (LASS), formed in platelets in response to thrombotic stimuli-purification, identification and unique biological significance

1974 • 178 citations

Prostaglandin endoperoxide and thromboxane generating systems and their selective inhibition

1976 • 176 citations

Dissociation of vasoconstrictor and platelet aggregatory activities of thromboxane by carbocyclic thromboxane A2, a stable analog of thromboxane A2.

1980 • 128 citations

13-Azaprostanoic acid: a specific antagonist of the human blood platelet thromboxane/endoperoxide receptor.

1979 • 113 citations

Synthesis and biological properties of pinane-thromboxane A2, a selective inhibitor of coronary artery constriction, platelet aggregation, and thromboxane formation.

1979 • 108 citations

Effect of Prostaglandin E2 and Aspirin on the Secondary Aggregation of Human Platelets

1972 • 101 citations

Potent luteolytic agents related to prostaglandin F2α

1974 • 94 citations

Highly stereoselective conversion of prostaglandin A2 to the 10, 11.alpha.-oxido derivative using a remotely placed exogenous directing group

1973 • 62 citations

Discrimination between platelet prostaglandin receptors with a specific antagonist of bisenoic prostaglandins

1977 • 59 citations

In vivo PHARMACOLOGICAL STUDIES ON THE INTERACTIONS BETWEEN TRYPTAMINE AND 5‐HYDROXYTRYPTAMINE

1981 • 41 citations

Synthesis of prostaglandin H2

1979 • 40 citations

Prostaglandins and platelet function.

1976 • 35 citations

Prostaglandin F2α antagonizes thromboxane A2-induced human platelet aggregation

1982 • 29 citations

Synthesis of prostanoids with bicyclo[2.2.1]heptane, bicyclo[3.1.1]heptane and bicyclo[2.2.2]octane ring systems. Activities of 15-hydroxy epimers on human platelets

1982 • 24 citations

Stereo-dependent inhibition of human platelet function by the optical isomers of trimetoquinol

1981 • 24 citations

Synthesis of thromboxane A2 analog DL-(9,11), (11,12)-dideoxa-(9,11)-epithio-(11,12)-methylene-thromboxane A2

1981 • 18 citations

ACTIONS OF 16‐ARYLOXY ANALOGUES OF PROSTAGLANDIN F_2α ON PREPARATIONS RESPONSIVE TO PROSTAGLANDIN ENDOPEROXIDES

1977 • 16 citations

THROMBOXANE-LIKE ACTIVITY OF PROSTANOIDS WITH AROMATIC SUBSTITUENTS AT C16 AND C17

1979 • 16 citations

Effects of thromboxane antagonist EP 045 on platelet aggregation.

1983 • 15 citations

Antiplatelet actions of trimetoquinol isomers: evidence for inhibition of a prostaglandin-independent pathway of platelet aggregation

1982 • 11 citations

Syntheses of thromboxane A2 analogs: Thia- and dithiathromboxane A2.

1983 • 1 citations