The use of isolated membrane vesicles to study epithelial transport processes

A modified procedure for the rapid preparation of efficiently transporting vesicles from small intestinal brush border membranes. Their use in investigating some properties of d-glucose and choline transport systems

1978 • 1,145 citations

Glucose Transport in Isolated Brush Border Membrane from Rat Small Intestine

1973 • 841 citations

Purification of the human intestinal brush border membrane

1973 • 799 citations

Sodium/proton antiport in brush-border-membrane vesicles isolated from rat small intestine and kidney

1976 • 665 citations

A rapid method for the preparation of microvilli from rabbit kidney

1974 • 608 citations

The digestive function of the epithelium of the small intestine

1961 • 388 citations

The gradient hypothesis and other models of carrier-mediated active transport

2005 • 327 citations

The digestive function of the epithelium of the small intestine

1961 • 285 citations

Phosphate transport into brush-border membrane vesicles isolated from rat small intestine

1976 • 264 citations

Studies on the orientation of brush-border membrane vesicles

1978 • 256 citations

THE POLARITY OF THE PROXIMAL TUBULE CELL IN RAT KIDNEY

1972 • 223 citations

The use of ion-exchange resins for studying ion transport in biological systems

1976 • 222 citations

Demonstration of Electrogenic Na ⁺ -dependent D-glucose Transport in Intestinal Brush Border Membranes

1974 • 217 citations

Studies on the enzymology of purified preparations of brush border from rabbit kidney

1973 • 212 citations

Calcium ion transport across plasma membranes isolated from rat kidney cortex

1979 • 212 citations

The electrochemical proton gradient in Escherichia coli membrane vesicles

1977 • 208 citations

The surface membrane of the small intestinal epithelial cell. I. Localization of adenyl cyclase

1976 • 186 citations

A simple and fast method for the isolation of basolateral plasma membranes from rat small-intestinal epithelial cells

1980 • 185 citations

Glucose transport in isolated brush-border and lateral-basal plasma-membrane vesicles from intestinal epithelila cells

1974 • 185 citations

[72] Transport in isolated bacterial membrane vesicles

1974 • 165 citations

The effect of 1alpha-hydroxyvitamin D3 administration on calcium transport in chick intestine brush border membrane vesicles.

1979 • 164 citations

Active alanine transport in isolated brush border membranes.

1975 • 163 citations

Energy-dependence of phlorizin binding to isolated renal microvillus membranes

1978 • 163 citations

ISOLATION AND BIOCHEMICAL CHARACTERIZATION OF BRUSH BORDERS FROM RABBIT KIDNEY

1970 • 154 citations

Properties of Brush Border Vesicles Isolated from Rat Kidney Cortex by Calcium Precipitation

1978 • 145 citations

Active Ca2+ reabsorption in the proximal tubule of the rat kidney

1976 • 144 citations

The sodium electrochemical potential-mediated uphill transport of D-glucose in renal brush border membrane vesicles

1978 • 141 citations

Coupling between proximal tubular transport processes

1977 • 133 citations

Sulphate-ion/sodium-ion co-transport by brush-border membrane vesicles isolated from rat kidney cortex

1979 • 130 citations

The Feldberg Lecture 1976. Solute transport across epithelia: what can we learn from micropuncture studies in kidney tubules?

1979 • 120 citations

The effects of potassium and membrane potential on sodium-dependent glutamic acid uptake

1980 • 119 citations

Transport of organic ions in renal cortical luminal and antiluminal membrane vesicles.

1979 • 118 citations

Transport in Membrane Vesicles Isolated from the Mammalian Kidney and Intestine

1977 • 118 citations

Pathways for alanine transport in intestinal basal lateral membrane vesicles

1980 • 117 citations

Vitamin D: Biochemical, Chemical and Clinical Aspects related to Calcium Metabolism

1979 • 117 citations

pH gradient-stimulated transport of urate and p-aminohippurate in dog renal microvillus membrane vesicles.

1980 • 116 citations

Membrane transport in biology

1980 • 114 citations

Purification and characterization of chick intestine brush border membrane Effects of 1α(OH) vitamin D3 treatment

1978 • 112 citations

The Isolation of a Brush Border Membrane Fraction from Rat Kidney

1970 • 111 citations

A simple apparatus for performing short-time (1–2 seconds) uptake measurements in small volumes; its application to d-glucose transport studies in brush border vesicles from rabbit jejunum and ileum

1978 • 109 citations

Competitive inhibition of phlorizin binding byd-glucose and the influence of sodium: a study on isolated brush border membrane of rat kidney

1970 • 106 citations

Similarity in effects of Na+ gradients and membrane potentials ond-glucose transport by, and phlorizin binding to, vesicles derived from brush borders of rabbit intestinal mucosal cells

1978 • 104 citations

On the mechanism of sugar and amino acid interaction in intestinal transport.

1975 • 99 citations

Isolation of luminal and antiluminal membranes from dog kidney cortex

1979 • 98 citations

Sarcomere motion in isolated cardiac cells

1979 • 96 citations

Differences in neutral amino acid and glucose transport between brush border and basolateral plasma membrane of intestinal epithelial cells

1976 • 95 citations

Taurocholate–sodium co-transport by brush-border membrane vesicles isolated from rat ileum

1978 • 94 citations

Coupled sodium and chloride transport into plasma membrane vesicles prepared from dogfish rectal gland

1978 • 90 citations

Na+-dependent, electroneutral l-ascorbate transport across brush border membrane vesicles from guinea pig small intestine

1979 • 89 citations

A distinct d-fructose transport system in isolated brush border membrane

1974 • 87 citations

Sugar uptake by intestinal basolateral membrane vesicles

1980 • 87 citations

Glutamine and glutamic acid uptake by rat renal brushborder membrane vesicles

1978 • 85 citations

A reconstituted Na++K+ pump in liposomes containing purified (Na++K+-ATPase from kidney medulla

1977 • 83 citations

Phosphate transport by rat renal brush border membrane vesicles: Influence of dietary phosphate, thyroparathyroidectomy, and 1,25-dihydroxyvitamin D3

1979 • 81 citations

Lactate-sodium cotransport in rat renal brush border membranes

1980 • 81 citations

Sodium-coupled Taurocholate Transport in the Proximal Convolution of the Rat Kidney In Vivo and In Vitro

1981 • 80 citations

Isolation and enzymatic characterisation of the brushborder-fraction of the rat kidney

1969 • 80 citations

Further evidence for the existence of an intrinsic bicarbonate-stimulated Mg2+-ATPase in brush border membranes isolated from rat kidney cortex

1979 • 78 citations

Renal Adaptation to a Low Phosphate Diet in Rats

1979 • 74 citations

Transport of tricarboxylic acid cycle intermediates by membrane vesicles from renal brush border.

1979 • 74 citations

Anion transport in brush border membranes isolated from rat small intestine

1977 • 73 citations

Preparation of renal cortex basal-lateral and brush border membranes. Localization of adenylate cyclase and guanylate cyclase activities

1977 • 71 citations

Sugar uptake into brush border vesicles from normal human kidney.

1977 • 71 citations

Proline and glycine uptake by renal brushborder membrane vesicles.

1976 • 71 citations

Membrane potential-sensitive fluorescence changes during Na+-dependent D-glucose transport in renal brush border membrane vesicles.

1978 • 70 citations

Sulfate-sodium cotransport by brush-border membrane vesicles isolated from rat ileum

1981 • 70 citations

Kinetics of Na⁺‐dependent D‐glucose transport

1977 • 69 citations

Transmembrane disposition of the phlorizin binding protein of intestinal brush borders

1979 • 63 citations

Sodium ion/L-lactate co-transport in rabbit small-intestinal brush-border-membrane vesicles

1980 • 58 citations

Localization of the membrane defect in transepithelial transport of taurine by parallel studies in vivo and in vitro in hypertaurinuric mice.

1976 • 58 citations

Reconstitution into liposomes of glucose active transport from the rabbit renal proximal tubule. Characteristics of the system

1979 • 58 citations

Isolated membrane vesicles as tools for analysis of epithelial transport.

1977 • 54 citations

Anion-stimulated ATPase activity of brush border from rat small intestine.

1979 • 50 citations

Isolated membrane vesicles in the evaluation of the nature, localization, and regulation of renal transport processes

1978 • 50 citations

Sodium-cotransport systems in intestine and kidney of the winter flounder

1980 • 47 citations

H+ transport by a non-electrogenic gastric ATpase as a model for acid secretion

1977 • 46 citations

Incorporation of <scp>d</scp>-glucose-, <scp>l</scp>-alanine- and phosphate-transport systems from rat renal brush-border membranes into liposomes

1977 • 46 citations

Uptake of d-Glucose by Renal Tubule Membranes

1972 • 42 citations

Highly purified basal lateral plasma membranes from rat duodenum. Physical criteria for purity

1979 • 41 citations

Transport of l-arginine in brush border vesicles derived from rabbit kidney cortex

1978 • 41 citations

Dipeptide transport in isolated intestinal brush border membrane

1975 • 40 citations

Sodium-Dependent Transport of Inorganic Phosphate Across the Renal Brush Border Membrane

1980 • 36 citations

Glycodeoxycholate transport in brush border membrane vesicles isolated from rat jejunum and ileum

1979 • 34 citations

Changes of intracellular Ca++ as measured by arsenazo III in relation to the K permeability of human erythrocyte ghosts

1978 • 32 citations

Plasma cell membranes of the rat kidney

1971 • 28 citations

RELATIONS BETWEEN LIPOSOMES AND BIOMEMBRANES

1978 • 26 citations

Jejunal and ileal d-glucose transport in isolated brush border membranes

1976 • 25 citations

On the efficiency of energy conversion in sodium‐driven D‐glucose transport across small intestinal brush border membrane vesicles: an estimation

1979 • 25 citations

Ion requirements for taurocholate transport by ileal brush border membrane vesicles

1979 • 25 citations

Transport Across Small Intestine

1979 • 25 citations

Recent observations on the proximal tubular transport of acidic and basic amino acids by rat renal proximal tubular brush border vesicles

1980 • 25 citations

Sidedness and Coupling of Transport Processes in Small Intestinal and Renal Epithelia

1977 • 23 citations

L-proline transport by newborn rat kidney brush-border membrane vesicles

1979 • 22 citations

The inhibitory effect of reserpine on the active sodium transport across the frog bladder

1976 • 21 citations

Reconstitution of N1-methylnicotinamide and p-aminohippuric acid transport in phospholipid vesicles with a protein fraction isolated from dog kidney membranes.

1979 • 16 citations

Anion-stimulated phosphohydrolase activity of intestinal alkaline phosphatase

1980 • 15 citations

Osmotically reactive plasma membrane vesicles prepared from rabbit kidney tubules by mild hypotonic lysis

1974 • 13 citations

PROTON TRANSLOCATION SYSTEMS IN RAT RENAL BRUSH BORDER MEMBRANES

1981 • 5 citations

ATP-hydrolysis as driving force for transport processes in isolated renal plasma membrane vesicles.

1977 • 4 citations

Optical Monitoring of Membrane Potential Changes as a Tool to Study Sodium-Dependent Substrate Transport in Brush Border Vesicles from Kidney Proximal Tubules

1979 • 2 citations