Genetic variation inGlp1rexpression influences the rate of gastric emptying in mice
Data up to Jan 2025
Total Citations Per Year
Abstract
References (64)
A comparison of normalization methods for high density oligonucleotide array data based on variance and bias
2003 • 8,139 citations
Empirical threshold values for quantitative trait mapping.
1994 • 4,967 citations
A role for glucagon-like peptide-1 in the central regulation of feeding
1996 • 1,880 citations
Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans.
1998 • 1,338 citations
Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1.
1992 • 880 citations
Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells.
1993 • 814 citations
Glucose intolerance but normal satiety in mice with a null mutation in the glucagon–like peptide 1 receptor gene
1996 • 771 citations
Truncated GLP-1 (proglucagon 78?107-amide) inhibits gastric and pancreatic functions in man
1993 • 661 citations
A Statistical Framework for Quantitative Trait Mapping
2001 • 632 citations
The volume and energy content of meals as determinants of gastric emptying.
1975 • 579 citations
Tissue distribution of messenger ribonucleic acid encoding the rat glucagon-like peptide-1 receptor.
1996 • 569 citations
Cloning and Functional Expression of the Human Islet GLP-1 Receptor: Demonstration That Exendin-4 Is an Agonist and Exendin-(9–39) an Antagonist of the Receptor
1993 • 533 citations
Strategies for mapping and cloning quantitative trait genes in rodents
2005 • 504 citations
Biological actions and therapeutic potential of the glucagon-like peptides
2002 • 496 citations
Interim analysis of the effects of exenatide treatment on A1C, weight and cardiovascular risk factors over 82 weeks in 314 overweight patients with type 2 diabetes
2006 • 427 citations
Glucagon-like peptide-1 inhibits gastric emptying via vagal afferent-mediated central mechanisms
1997 • 407 citations
Detection of regulatory variation in mouse genes
2002 • 393 citations
Divergent tissue-specific and developmental expression of receptors for glucagon and glucagon-like peptide-1 in the mouse.
1994 • 321 citations
Peripheral Exendin-4 and Peptide YY3–36 Synergistically Reduce Food Intake through Different Mechanisms in Mice
2005 • 302 citations
Glucagon-like peptide 1 increases the period of postprandial satiety and slows gastric emptying in obese men
1998 • 298 citations
Glucagon-like peptide 1(GLP-1) in biology and pathology
2005 • 283 citations
GLP-1 slows solid gastric emptying and inhibits insulin, glucagon, and PYY release in humans
1999 • 277 citations
Cis-Acting Regulatory Variation in the Human Genome
2004 • 269 citations
Cholecystokinin inhibits gastric motility and emptying via a capsaicin-sensitive vagal pathway in rats
1988 • 265 citations
Endogenous glucagon-like peptide 1 controls endocrine pancreatic secretion and antro-pyloro-duodenal motility in humans
2005 • 260 citations
Effect of GLP-1 on gastric volume, emptying, maximum volume ingested, and postprandial symptoms in humans
2002 • 216 citations
Glucagon-like peptide-1 inhibits gastropancreatic function by inhibiting central parasympathetic outflow
1998 • 190 citations
Structural Model Analysis of Multiple Quantitative Traits
2006 • 174 citations
THE PORTAL TRANSPORT OF ABSORBED FATTY ACIDS
1952 • 168 citations
Tissue distribution of rat glucagon receptor and GLP-1 receptor gene expression1This work was supported by a grant from the Crohn's and Colitis Foundation of America.1
1998 • 159 citations
Structure-Function of the Glucagon Receptor Family of G Protein-Coupled Receptors: The Glucagon, GIP, GLP-1, and GLP-2 Receptors
2002 • 158 citations
Mice, gene targeting and behaviour: more than just genetic background
1996 • 150 citations
Structure-Function of the Glucagon Receptor Family of G Protein-Coupled Receptors: The Glucagon, GIP, GLP-1, and GLP-2 Receptors
2002 • 138 citations
Intravenous infusion of glucagon-like peptide-1 potently inhibits food intake, sham feeding, and gastric emptying in rats
2005 • 127 citations
Intraventricular GLP-1 reduces short- but not long-term food intake or body weight in lean and obese rats
1998 • 122 citations
Delayed gastric emptying in the obese: an assessment using the non‐invasive 13C‐octanoic acid breath test
2004 • 113 citations
An alternate pathway of cAMP-stimulated Cl− secretion across the NKCC1-null murine duodenum
2002 • 94 citations
Peripheral urocortin inhibits gastric emptying and food intake in mice: differential role of CRF receptor 2
2001 • 91 citations
Relation between gastric emptying of glucose and plasma concentrations of glucagon-like peptide-1
1998 • 88 citations
GLP-1 and Extra-islet Effects
2004 • 68 citations
Reflex decreases in intragastric pressure in response to cholecystokinin in rats
1987 • 68 citations
QTL analysis of self-selected macronutrient diet intake: fat, carbohydrate, and total kilocalories
2002 • 68 citations
Characterization of high‐affinity receptors for truncated glucagon‐like peptide‐1 in rat gastric glands
1990 • 67 citations
INCREASED FAT AND DECREASED CARBOHYDRATE APPETITE OF PANCREATECTOMIZED RATS
1941 • 65 citations
13C octanoic acid breath test
1998 • 58 citations
Rat parietal cell receptors for GLP-1-(7-36) amide: northern blot, cross-linking, and radioligand binding
1994 • 52 citations
Assessment Of Gastric Emptying In The Mouse Using The [13C]‐Octanoic Acid Breath Test
2000 • 50 citations
Inhibitory effect of GLP-1 on gastric motility persists after vagal deafferentation in pigs
2006 • 43 citations
Detection of Allelic Imbalance in Gene Expression Using Pyrosequencing<sup>®</sup>
2007 • 39 citations
Patterns of nutrient selection in rats with streptozotocin-induced diabetes
1984 • 37 citations
Interaction with grp58 increases activity of the thiazide-sensitive Na-Cl cotransporter
2002 • 36 citations
Fecal 13C analysis for the detection and quantitation of intestinal malabsorption. Limits of detection and application to disorders of intestinal cholylglycine metabolism.
1981 • 35 citations
The 13C-octanoic acid breath test: validation of a new noninvasive method of measuring gastric emptying in rats
2002 • 33 citations
Quantitative trait loci for carbohydrate and total energy intake on mouse chromosome 17: congenic strain confirmation and candidate gene analyses (Glo1,Glp1r)
2006 • 31 citations
Noninvasive breath tests can detect alterations in gastric emptying in the mouse
2002 • 26 citations
Diet selection and metabolic fuels in three models of diabetes mellitus
1983 • 23 citations
The cytoplasmic domain close to the transmembrane region of the glucagon-like peptide-1 receptor contains sequence elements that regulate agonist-dependent internalisation
2005 • 21 citations
Contraction induced by glicentin on smooth muscle cells from the human colon is abolished by exendin (9–39)
2005 • 20 citations
The effect of the GABAB receptor agonist baclofen on liquid and solid gastric emptying in mice
2003 • 20 citations
Rate of gastric emptying influences dietary cholesterol absorption efficiency in selected inbred strains of mice
2004 • 19 citations
Mappingcis-acting regulatory variation in recombinant congenic strains
2006 • 19 citations
Gut Peptides and Other Regulators in Obesity
2004 • 17 citations
Decreased gastric mechanodetection, but preserved gastric emptying, in CCK-1 receptor-deficient OLETF rats
2006 • 9 citations
Gastric emptying evaluation by 13C-octanoic acid breath test.
2004 • 4 citations