Is This the Drug or Dose for You?: Impact and Consideration of Ethnic Factors in Global Drug Development, Regulatory Review, and Clinical Practice

Use of Pharmacogenetic and Clinical Factors to Predict the Therapeutic Dose of Warfarin

2008 • 805 citations

Drug Interaction Studies: Study Design, Data Analysis, and Implications for Dosing and Labeling

2007 • 567 citations

The Role of Ethnicity in Variability in Response to Drugs: Focus on Clinical Pharmacology Studies

2008 • 376 citations

Pharmacokinetics/Genotype Associations for Major Cytochrome P450 Enzymes in Native and First- and Third-generation Japanese Populations: Comparison With Korean, Chinese, and Caucasian Populations

2008 • 219 citations

Improving Pediatric Dosing Through Pediatric Initiatives: What We Have Learned

2008 • 157 citations

Dosing Algorithms to Predict Warfarin Maintenance Dose in Caucasians and African Americans

2008 • 122 citations

Integration and Use of Biomarkers in Drug Development, Regulation and Clinical Practice: a US Regulatory Perspective

2008 • 113 citations

BiDil for Heart Failure in Black Patients: The U.S. Food and Drug Administration Perspective

2007 • 99 citations

The Critical Path of Warfarin Dosing: Finding an Optimal Dosing Strategy Using Pharmacogenetics

2008 • 75 citations

Same Drug, Different Dosing: Differences in Dosing for Drugs Approved in the United States, Europe, and Japan

2008 • 71 citations

Individual Genomes Instead of Race for Personalized Medicine

2008 • 71 citations

Genetic Variation in Drug Transporters in Ethnic Populations

2008 • 56 citations

Racial Differences in Blood Pressure Response to Angiotensin-Converting Enzyme Inhibitors in Children: A Meta-Analysis

2008 • 39 citations

Characteriation of Clinical Data Packages Using Foreign Data in New Drug Applications in Japan

2007 • 7 citations