Chromosome 13 Deletion/Hypodiploidy and Prognosis in Multiple Myeloma Patients

A Phase 2 Study of Bortezomib in Relapsed, Refractory Myeloma

2003 • 2,642 citations

A PROSPECTIVE, RANDOMIZED TRIAL OF AUTOLOGOUS BONE MARROW TRANSPLANTATION AND CHEMOTHERAPY IN MULTIPLE MYELOMA

2013 • 2,176 citations

High-Dose Chemotherapy with Hematopoietic Stem-Cell Rescue for Multiple Myeloma

2003 • 1,759 citations

Experimental Hematology

2003 • 736 citations

Superiority of Tandem Autologous Transplantation Over Standard Therapy for Previously Untreated Multiple Myeloma

1997 • 576 citations

Graft-versus-myeloma effect: proof of principle

1996 • 565 citations

Extended survival in advanced and refractory multiple myeloma after single-agent thalidomide: identification of prognostic factors in a phase 2 study of 169 patients

2001 • 553 citations

The New England journal of medicine

1994 • 490 citations

Allografting with nonmyeloablative conditioning following cytoreductive autografts for the treatment of patients with multiple myeloma

2003 • 421 citations

The clinical significance of cytogenetic studies in 100 patients with multiple myeloma, plasma cell leukemia, or amyloidosis

1985 • 419 citations

Hypodiploidy is a major prognostic factor in multiple myeloma

2001 • 394 citations

Cytogenetic findings in 200 patients with multiple myeloma

1995 • 378 citations

Allogeneic bone marrow transplantation versus autologous stem cell transplantation in multiple myeloma: a retrospective case-matched study from the European Group for Blood and Marrow Transplantation

1996 • 376 citations

Progress in allogeneic bone marrow and peripheral blood stem cell transplantation for multiple myeloma: a comparison between transplants performed 1983–93 and 1994–98 at European Group for Blood and Marrow Transplantation centres

2001 • 349 citations

Results of high-dose therapy for 1000 patients with multiple myeloma: durable complete remissions and superior survival in the absence of chromosome 13 abnormalities

2000 • 333 citations

Allogeneic marrow transplantation for multiple myeloma: an analysis of risk factors on outcome

1996 • 332 citations

Recurrent 14q32 translocations determine the prognosis of multiple myeloma, especially in patients receiving intensive chemotherapy

2002 • 324 citations

Impact on survival of high-dose therapy with autologous stem cell support in patients younger than 60 years with newly diagnosed multiple myeloma: a population-based study

2000 • 317 citations

Plasma cell myeloma--new biological insights and advances in therapy

1989 • 299 citations

Plasma cell myeloma--new biological insights and advances in therapy

1989 • 263 citations

Improved cytogenetics in multiple myeloma: a study of 151 patients including 117 patients at diagnosis

1995 • 238 citations

European Journal of Cancer

2002 • 236 citations

Multiple myeloma: high incidence of chromosomal aneuploidy as detected by interphase fluorescence in situ hybridization.

1995 • 206 citations

Cytogenetics and their prognostic value in de novo acute myeloid leukaemia: a report on 283 cases

1989 • 205 citations

Hypodiploidy with less than 45 chromosomes confers adverse risk in childhood acute lymphoblastic leukemia : A report from the children's cancer group

1999 • 205 citations

Unique role of cytogenetics in the prognosis of patients with myeloma receiving high-dose therapy and autotransplants.

1997 • 187 citations

Prognostic Value of Numerical Chromosome Aberrations in Multiple Myeloma: A FISH Analysis of 15 Different Chromosomes

1998 • 180 citations

Chromosomal analysis in multiple myeloma: cytogenetic evidence of two different diseases

1998 • 170 citations

Both hypodiploidy and deletion of chromosome 13 independently confer poor prognosis in multiple myeloma

2002 • 163 citations

Prognostic impact of cytogenetic and interphase fluorescence in situ hybridization‐defined chromosome 13 deletion in multiple myeloma: early results of total therapy II

2002 • 159 citations

Ploidy and proliferative characteristics in monoclonal gammopathies

1982 • 149 citations

Prognostic value of cytogenetics in multiple myeloma

1998 • 145 citations

Interphase fluorescence in situ hybridization identifies chromosomal abnormalities in plasma cells from patients with monoclonal gammopathy of undetermined significance

1995 • 143 citations

Continuous absence of metaphase-defined cytogenetic abnormalities, especially of chromosome 13 and hypodiploidy, ensures long-term survival in multiple myeloma treated with Total Therapy I: interpretation in the context of global gene expression

2003 • 134 citations

Prognostic implications of tumor cell DNA and RNA content in multiple myeloma

1985 • 113 citations

Cellular DNA content as a marker of human multiple myeloma

1980 • 113 citations

Prognostic factors in allogeneic transplantation for patients with high-risk multiple myeloma after reduced intensity conditioning

2003 • 95 citations

Predicting long‐term (≥ 5 years) event‐free survival in multiple myeloma patients following planned tandem autotransplants

2002 • 93 citations

Karyotype in multiple myeloma and plasma cell leukaemia

1993 • 88 citations

Prognostic implications of DNA aneuploidy in 156 untreated multiple myeloma patients

1995 • 83 citations

Prognostic and biological importance of chromosome findings in acute lymphoblastic leukemia

1990 • 80 citations

Monoclonal gammopathy of undetermined significance: chromosome changes are a common finding within bone marrow plasma cells

1995 • 70 citations

Why better prognostic factors for multiple myeloma are needed [editorial] [see comments]

1994 • 59 citations

Proteasome inhibitors induce growth inhibition and apoptosis in myeloma cell lines and in human bone marrow myeloma cells irrespective of chromosome 13 deletion

2003 • 50 citations

Hypodiploidy and 22q11 rearrangements at diagnosis are associated with poor prognosis in patients with multiple myeloma

1997 • 48 citations

Tumor DNA content as a prognostic indicator in squamous cell carcinoma of the oral cavity and tongue base

1998 • 44 citations

Is Flow Cytometric DNA Content Hypodiploidy Prognostic in Multiple Myeloma?

1999 • 40 citations

Hypodiploidy, Ki-67 growth fraction and prognosis of surgically resected lung cancers

1996 • 35 citations

MDS‐type abnormalities within myeloma signature karyotype (MM‐MDS): only 13% 1‐year survival despite tandem transplants

2003 • 35 citations

British Journal of Haematology

2003 • 23 citations

DNA and RNA flow cytometric study in multiple myeloma. Clinical correlations

1991 • 20 citations

Predicting Long-term Survival in Multiple Myeloma Patients Following Autotransplants

2003 • 10 citations

Cancer genetics and cytogenetics

1996 • 9 citations