Prognostic Value of Numerical Chromosome Aberrations in Multiple Myeloma: A FISH Analysis of 15 Different Chromosomes

Analysis of Survival Data

1984 • 6,206 citations

A Cell Cycle Regulator Potentially Involved in Genesis of Many Tumor Types

1994 • 2,821 citations

Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

1994 • 1,806 citations

Superiority of Tandem Autologous Transplantation Over Standard Therapy for Previously Untreated Multiple Myeloma

1997 • 576 citations

Localization of gene for human p53 tumour antigen to band 17p13

1986 • 498 citations

The clinical significance of cytogenetic studies in 100 patients with multiple myeloma, plasma cell leukemia, or amyloidosis

1985 • 419 citations

Poor prognosis in multiple myeloma is associated only with partial or complete deletions of chromosome 13 or abnormalities involving 11q and not with other karyotype abnormalities

1995 • 418 citations

Cytogenetic findings in 200 patients with multiple myeloma

1995 • 378 citations

Plasma cell labeling index and beta 2-microglobulin predict survival independent of thymidine kinase and C-reactive protein in multiple myeloma [see comments]

1993 • 321 citations

C-reactive protein and beta-2 microglobulin produce a simple and powerful myeloma staging system

1992 • 296 citations

Improved cytogenetics in multiple myeloma: a study of 151 patients including 117 patients at diagnosis

1995 • 238 citations

Human p53 gene localized to short arm of chromosome 17

1986 • 222 citations

Multiple myeloma: high incidence of chromosomal aneuploidy as detected by interphase fluorescence in situ hybridization.

1995 • 206 citations

Limits of detection of nuclear DNA abnormalities by flow cytometric DNA analysis. Results obtained by a set of methods for sample‐storage, staining and internal standardization

1983 • 202 citations

Frequent Hypermethylation of p16 and p15 Genes in Multiple Myeloma

1997 • 195 citations

In situhybridisation with fluoresceinated DNA

1991 • 192 citations

Structure and function of p53 in normal cells and their aberrations in cancer cells: projection on the hematologic cell lineages

1994 • 179 citations

A new staging system for multiple myeloma based on the number of S- phase plasma cells

1995 • 143 citations

Structure and function of p53 in normal cells and their aberrations in cancer cells: projection on the hematologic cell lineages

1994 • 142 citations

Distinct regions of allelic loss on 13q in prostate cancer.

1996 • 140 citations

Frequent loss of heterozygosity on chromosome 6 in human ovarian carcinoma

1993 • 126 citations

Inactivation of tumor suppressor genes, p53 and Rb1, in plasma cell dyscrasias.

1994 • 110 citations

A new staging system for multiple myeloma based on the number of S- phase plasma cells

1995 • 107 citations

Interphase cytogenetics of brain tumors

1991 • 104 citations

Chronic lymphocytic leukemia cells with allelic deletions at 13q14 commonly have one intact RB1 gene: evidence for a role of an adjacent locus.

1993 • 102 citations

Immunophenotypic heterogeneity of multiple myeloma: influence on the biology and clinical course of the disease

1991 • 102 citations

Deletion of the retinoblastoma gene in multiple myeloma.

1994 • 90 citations

Incidence of chromosome numerical changes in multiple myeloma: fluorescence in situ hybridization analysis using 15 chromosome-specific probes.

1996 • 89 citations

Chromosome 13q deletion mapping in head and neck squamous cell carcinomas: identification of two distinct regions of preferential loss.

1996 • 87 citations

Prognostic implications of DNA aneuploidy in 156 untreated multiple myeloma patients

1995 • 83 citations

A new method for the analysis of plasma cell DNA content in multiple myeloma samples using a CD38/propidium iodide double staining technique

1994 • 81 citations

Human myeloma in vitro colony growth: interrelationships between drug sensitivity, cell kinetics, and patient survival duration

1983 • 79 citations

Analysis of natural killer‐associated antigens in peripheral blood and bone marrow of multiple myeloma patients and prognostic implications

1996 • 78 citations

Multiple regions of chromosome 6q affected by loss of heterozygosity in primary human breast carcinomas

1996 • 72 citations

Alternating combination VCMP/VBAP chemotherapy versus melphalan/prednisone in the treatment of multiple myeloma: a randomized multicentric study of 487 patients.

1993 • 64 citations

Cellular and Molecular Genetic Features of Myeloma and Related Disorders

1992 • 61 citations

Biclonal and hypodiploid multiple myeloma

1986 • 59 citations

Detection of hypodiploidy using multi‐parameter flow cytometric analysis: A prognostic indicator in multiple myeloma

1989 • 50 citations

High incidence of deletions but infrequent inactivation of the retinoblastoma gene in human myeloma cells

1995 • 42 citations

The Retinoblastoma Gene (RB-1) Status in Multiple Myeloma: A Report on 35 Cases

1995 • 36 citations

Multiple myeloma: biological and clinical significance of bone marrow plasma cell labelling index.

1987 • 25 citations

Involvement of chromosome 6 in endometrial cancer

1997 • 18 citations

Interleukin-3 plus interleukin-6 may improve chromosomal analysis of multiple myeloma: Cytologic and cytogenetic evidence in thirty-four patients

1996 • 13 citations