Back to search

CEACAM1-4S, a cell–cell adhesion molecule, mediates apoptosis and reverts mammary carcinoma cells to a normal morphogenic phenotype in a 3D culture

Data up to Jan 2025

Published2003
Citations168
References41

Total Citations Per Year

Abstract

References (41)

Caspase-3 Is Required for DNA Fragmentation and Morphological Changes Associated with Apoptosis

1998 • 1,927 citations

Reversion of the Malignant Phenotype of Human Breast Cells in Three-Dimensional Culture and In Vivo by Integrin Blocking Antibodies

1997 • 1,444 citations

Suppression of ICE and Apoptosis in Mammary Epithelial Cells by Extracellular Matrix

1995 • 1,184 citations

Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells.

1992 • 1,047 citations

The role of phosphatidylserine in recognition of apoptotic cells by phagocytes

1998 • 724 citations

Immunocytochemical detection and mapping of a cytokeratin 18 neo-epitope exposed during early apoptosis

1999 • 639 citations

Reciprocal interactions between β1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: A different perspective in epithelial biology

1998 • 625 citations

Signals for death and survival: A two-step mechanism for cavitation in the vertebrate embryo

1995 • 601 citations

Caspase Cleavage of Keratin 18 and Reorganization of Intermediate Filaments during Epithelial Cell Apoptosis

1997 • 596 citations

ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini

2001 • 559 citations

CEA adhesion molecules: multifunctional proteins with signal-regulatory properties

1997 • 284 citations

Biliary glycoprotein, a potential human cell adhesion molecule, is down-regulated in colorectal carcinomas.

1993 • 230 citations

Tumor suppressive role of an androgen-regulated epithelial cell adhesion molecule (C-CAM) in prostate carcinoma cell revealed by sense and antisense approaches.

1995 • 175 citations

Carcinoembryonic antigens: alternative splicing accounts for the multiple mRNAs that code for novel members of the carcinoembryonic antigen family.

1989 • 173 citations

Molecular cloning of a cDNA coding biliary glycoprotein I: primary structure of a glycoprotein immunologically crossreactive with carcinoembryonic antigen.

1988 • 150 citations

Inhibition of colonic tumor cell growth by biliary glycoprotein.

1995 • 150 citations

Biliary glycoprotein, a member of the immunoglobulin supergene family, functions in vitro as a Ca2(+)-dependent intercellular adhesion molecule.

1990 • 119 citations

Division of Labor among the α6β4 Integrin, β1 Integrins, and an E3 Laminin Receptor to Signal Morphogenesis and β-Casein Expression in Mammary Epithelial Cells

1999 • 118 citations

Essential role of biliary glycoprotein (CD66a) in morphogenesis of the human mammary epithelial cell line MCF10F

1999 • 102 citations

Differential Expression of CD66a (BGP), a Cell Adhesion Molecule of the Carcinoembryonic Antigen Family, in Benign, Premalignant, and Malignant Lesions of the Human Mammary Gland

1997 • 100 citations

Altered expression of E-cadherin in breast cancer

2000 • 97 citations

Homotypic and heterotypic Ca++-independent cell adhesion activities of biliary glycoprotein, a member of carcinoembryonic antigen family, expressed on CHO cell surface

1992 • 92 citations

Human biliary glycoprotein gene: characterization of a family of novel alternatively spliced RNAs and their expressed proteins.

1993 • 92 citations

Expression of CD66a (human C-CAM) and other members of the carcinoembryonic antigen gene family of adhesion molecules in human colorectal adenomas.

1997 • 86 citations

cis-Determinants in the cytoplasmic domain of CEACAM1 responsible for its tumor inhibitory function

1999 • 86 citations

A mouse carcinoembryonic antigen gene family member is a calcium-dependent cell adhesion molecule.

1991 • 83 citations

cis Interaction of the Cell Adhesion Molecule CEACAM1 with Integrin β3

2001 • 74 citations

Carcinoembryonic Antigen Cell Adhesion Molecule 1 Directly Associates with Cytoskeleton Proteins Actin and Tropomyosin

2001 • 73 citations

Expression of biliary glycoprotein (CD66a) in normal and malignant breast epithelial cells.

1998 • 64 citations

Purification and properties of biliary glycoprotein I (BGP I). Immunochemical relationship to carcinoembryonic antigen

1979 • 61 citations

Cell surface localization and tissue distribution of a hepatocyte cell-cell adhesion glycoprotein (cell-CAM 105)

1983 • 57 citations

The N-domain of the biliary glycoprotein (BGP) adhesion molecule mediates homotypic binding: domain interactions and epitope analysis of BGPc

1994 • 52 citations

Identification of membrane antigens in granulocytes and colonic carcinoma cells by a monoclonal antibody specific for biliary glycoprotein, a member of the carcinoembryonic antigen family

1991 • 50 citations

Characterization of protein kinase C‐mediated phosphorylation of the short cytoplasmic domain isoform of C‐CAM

1998 • 44 citations

Separated human breast epithelial and myoepithelial cells have different growth factor requirements in vitro but can reconstitute normal breast lobuloalveolar structure

1997 • 40 citations

Cell- and region-specific expression of biliary glycoprotein and its messenger RNA in normal human colonic mucosa.

1995 • 34 citations

Downstream events in mammary gland morphogenesis mediated by reexpression of the alpha2beta1 integrin: the role of the alpha6 and beta4 integrin subunits.

1998 • 32 citations

DIFFERENTIAL EXPRESSION OF C-CAM CELL ADHESION MOLECULE IN PROSTATE CARCINOGENESIS IN A TRANSGENIC MOUSE MODEL

1999 • 30 citations

Function and therapeutic implication of C-CAM cell-adhesion molecule in prostate cancer.

1999 • 26 citations

The Cytoplasmic Domain of C-CAM1 Tumor Suppressor Is Necessary and Sufficient for Suppressing the Tumorigenicity of Prostate Cancer Cells

1999 • 22 citations

Human Biliary Glycoprotein Gene: Characterization of a Family of Novel Alternatively Spliced RNAs and Their Expressed Proteins

1993 • 13 citations

Cited By (0)

No citing papers found in database

CEACAM1-4S, a cell–cell adhesion molecule, mediates apoptosis and reverts mammary… (2003) – Proceedings of the National Academy of Sciences | Metascience Observatory Explorer