The Chemical Form of Selenium Influences 3,2′-Dimethyl-4-aminobiphenyl-DNA Adduct Formation in Rat Colon

Glutathione S-Transferases

1974 • 17,321 citations

Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase.

1967 • 10,659 citations

Report of the American Institute of Nutrition Ad Hoc Committee on Standards for Nutritional Studies

1977 • 2,748 citations

Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin. A randomized controlled trial. Nutritional Prevention of Cancer Study Group

1996 • 2,404 citations

Food, nutrition and the prevention of cancer : a global perspective

1997 • 1,892 citations

Effects of Selenium Supplementation for Cancer Prevention in Patients With Carcinoma of the Skin

1996 • 1,807 citations

³²P-postlabeling analysis of non-radioactive aromatic carcinogen — DNA adducts

1982 • 653 citations

Role of aberrant crypt foci in understanding the pathogenesis of colon cancer

1995 • 578 citations

Nonrandom binding of the carcinogen N-hydroxy-2-acetylaminofluorene to repetitive sequences of rat liver DNA in vivo.

1984 • 529 citations

The Role of Glutathione and Glutathione Transferases in Chemical Cardnogenesi

1990 • 466 citations

Aberrant crypts: putative preneoplastic foci in human colonic mucosa.

1991 • 448 citations

Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon

1991 • 340 citations

Hepatic microsomal N-glucuronidation and nucleic acid binding of N-hydroxy arylamines in relation to urinary bladder carcinogenesis.

1977 • 325 citations

Human biomonitoring and the ³²P-postlabeling assay

1992 • 308 citations

Aberrant crypts correlate with tumor incidence in F344 rats treated with azoxymethane and phytate

1992 • 287 citations

Serum Selenium and Subsequent Risk of Cancer Among Finnish Men and Women

1990 • 279 citations

CYP1A2-catalyzed conversion of dietary heterocyclic amines to their proximate carcinogens is their major route of metabolism in humans.

1994 • 253 citations

Hepatic Cytosolic Non Selenium-Dependent Glutathione Peroxidase Activity: Its Nature and the Effect of Selenium Deficiency

1978 • 240 citations

Activity of methylated forms of selenium in cancer prevention.

1990 • 214 citations

Selenium in Forage Crops and Cancer Mortality in U.S. Counties

1991 • 206 citations

Pathways of Selenium Metabolism Including Respiratory Excretory Products

1986 • 188 citations

³²P-Postlabeling analysis of DNA adducts persisting for up to 42 weeks in the skin, epidermis and dermis of mice treated topically with 7,12-dimethylbenz[a]anthracene

1985 • 157 citations

Effects of Dietary Selenite, Selenocystine and Selenomethionine on Selenocysteine Lyase and Glutathione Peroxidase Activities and on Selenium Levels in Rat Tissues

1987 • 123 citations

32P-postlabeling assay in mice of transplacental DNA damage induced by the environmental carcinogens safrole, 4-aminobiphenyl, and benzo(a)pyrene.

1986 • 122 citations

Inhibition of 7,12-dimethylbenz(a)anthracene-induced tumors and DNA adduct formation in the mammary glands of female Sprague-Dawley rats by the synthetic organoselenium compound, 1,4-phenylenebis(methylene)selenocyanate.

1992 • 120 citations

Selenium effects on the carcinogenicity and metabolism of 2-acetylaminofluorene

1979 • 117 citations

Identification of dysplasia in human colonic aberrant crypt foci.

1997 • 100 citations

Selenium content of foods purchased in North Dakota

1996 • 91 citations

Effect of an inorganic and organic form of dietary selenium on the promotional stage of mammary carcinogenesis in the rat.

1984 • 85 citations

Alteration of urinary levels of the carcinogen, N-hydroxy-2-naphthylamine, and its N-glucuronide in the rat by control of urinary pH, inhibition of metabolic sulfation, and changes in biliary excretion

1981 • 83 citations

Tissue selenium levels in selenium-supplemented rats and their relevance in mammary cancer protection

1989 • 82 citations

The metabolism of selenomethionine, Se-methylselenocysteine, their selenonium derivatives, and trimethylselenonium in the rat

1986 • 81 citations

Characterisation of aberrant crypt foci in carcinogen-treated rats: association with intestinal carcinogenesis

1995 • 77 citations

Selenium inhibition of chemical carcinogenesis.

1985 • 76 citations

Influence of Dietary Methionine on the Metabolism of Selenomethionine in Rats

1989 • 72 citations

Essential Nutrients in Carcinogenesis

1986 • 67 citations

Enzymatic phase II activation of the N-hydroxylamines of IQ, MelQx and PhIP by various organs of monkeys and rats

1993 • 67 citations

Some effects of selenium deficiency on the hepatic microsomal cytochrome P-450 system in the rat

1975 • 66 citations

Human aberrant crypt foci with carcinoma in situ from a patient with sporadic colon cancer

1996 • 58 citations

Inhibition of human cytochrome P450-catalyzed oxidations of xenobiotics and procarcinogens by synthetic organoselenium compounds.

1997 • 51 citations

DNA adducts formed from the probable proximate carcinogen, N-hydroxy-3,2′ -dimethyl-4-aminobiphenyl, by acid catalysis or S-acetyl coenzyme A-dependent enzymatic esterification

1985 • 48 citations

Chemoprevention of mammary cancer by diallyl selenide, a novel organoselenium compound.

1996 • 46 citations

Differential Effect of Dietary Methionine on the Biopotency of Selenomethionine and Selenite in Cancer Chemoprevention1

1988 • 45 citations

Effect of germanium on 1, 2-dimethylhydrazine-induced intestinal cancer in rats

1990 • 44 citations

Evaluation of organoselenium compounds for potential chemopreventive properties in colon carcinogenesis.

1994 • 43 citations

Different carcinogenic responses in a variety of organs, including the prostate, of five different rat strains given 3,2′-dimethyl-4-aminobiphenyl

1990 • 43 citations

Regulation of Glutathione S-Transferase Gene Expression and Activity by Dietary Selenium

1994 • 36 citations

Expression of three major protein kinase C isozymes in various types of human leukemic cells.

1991 • 35 citations

Dietary Selenium and Antioxidant Status: Toxic Effects of 1,2-Dimethylhydrazine in Rats

1991 • 35 citations

Formation of DNA adducts in vivo in rat liver and intestinal epithelium after administration of the carcinogen 3,2'-dimethyl-4-aminobiphenyl and its hydroxamic acid

1985 • 27 citations

In vivo metabolism of 3,2'-dimethyl-4-aminobiphenyl (DMAB) bearing on its organotropism in the Syrian golden hamster and the F344 rat.

1983 • 23 citations

Effect of Dietary Selenium Deficiency on Incidence and Size of 1,2-Dimethylhydrazine-Induced Colon Tumors in Rats

1985 • 23 citations

Inhibition of Chemical Carcinogenesis and Tumorigenesis by Selenium

1986 • 22 citations

Higher Frequency of Aberrant Crypt Foci in Rapid Than Slow Acetylator Inbred Rats Administered the Colon Carcinogen 3,2′-Dimethyl-4-aminobiphenyl

1997 • 22 citations

Age, Dietary Selenium and Quantity of 7,12-Dimethylbenz(a)anthracene Influence the in Vivo Occurrence of Rat Mammary DNA Adducts

1992 • 22 citations

The effect of dietary selenium deficiency on acute colorectal mucosal nucleotoxicity induced by several carcinogens in the rodent

1996 • 21 citations

The antimutagenic effect of selenium on 7,12-dimethylbenz(a)anthracene and metabolites in the amesSalmonella/microsome system

1982 • 16 citations

Effect of Selenium on 1,2-dimethylhydrazine-induced intestinal cancer in rats

1996 • 15 citations

Structure-activity relationships among the ortho-, meta- and para-isomers of phenylenebis (methylene)seleno cyanate (XSC) as inhibitors of 7,12-dimethylbenz(a)anthracene-DNA binding in mammary glands of female CD rats

1997 • 7 citations