Redesigning the hydrophobic core of a four‐helix‐bundle protein

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Some Factors in the Interpretation of Protein Denaturation

1959 • 4,817 citations

Dominant forces in protein folding

1990 • 3,682 citations

X-PLOR Version 3.1: A System for X-ray Crystallography and NMR

1992 • 3,488 citations

[14]Determination and analysis of urea and guanidine hydrochloride denaturation curves

1986 • 2,265 citations

Tertiary templates for proteins

1987 • 1,485 citations

A Switch Between Two-, Three-, and Four-stranded Coiled Coils in GCN4 Leucine Zipper Mutants

1993 • 1,456 citations

The molten globule state as a clue for understanding the folding and cooperativity of globular‐protein structure

1989 • 1,446 citations

Trans-complementable copy-number mutants of plasmid ColE1

1980 • 975 citations

A lattice statistical mechanics model of the conformational and sequence spaces of proteins

1989 • 962 citations

Protein Design by Binary Patterning of Polar and Nonpolar Amino Acids

1993 • 737 citations

Biochemical Applications of Differential Scanning Calorimetry

1987 • 592 citations

Characterization of a Helical Protein Designed from First Principles

1988 • 533 citations

De Novo Design, Expression, and Characterization of Felix: a Four-Helix Bundle Protein of Native-Like Sequence

1990 • 392 citations

Alternative packing arrangements in the hydrophobic core of λrepresser

1989 • 375 citations

α-Helical coiled coils — a widespread motif in proteins

1986 • 350 citations

Energetics of complementary side chain packing in a protein hydrophobic core

1989 • 346 citations

Structure of the ColE1 Rop protein at 1.7 Å resolution

1987 • 297 citations

Mutant forms of staphylococcal nuclease with altered patterns of guanidine hydrochloride and urea denaturation

1986 • 275 citations

The role of internal packing interactions in determining the structure and stability of a protein

1991 • 208 citations

Scanning microcalorimeters for studying macromolecules

1980 • 189 citations

Stability mutants of staphylococcal nuclease: large compensating enthalpy-entropy changes for the reversible denaturation reaction

1988 • 149 citations

p22 Arc Repressor: Folding Kinetics of a Single-Domain, Dimeric Protein

1994 • 138 citations

Complex formed by complementary RNA stem-loops and its stabilization by a protein: Function of ColE1 Rom protein

1990 • 123 citations

The Role of Backbone Flexibility in the Accommodation of Variants That Repack the Core of T4 Lysozyme

1993 • 122 citations

ColE1 replication control circuitry: Sense from antisense

1988 • 111 citations

The protein-folding problem: the native fold determines packing, but does packing determine the native fold?

1991 • 101 citations

Subunit interactions provide a significant contribution to the stability of the dimeric four-.alpha.-helical-bundle protein ROP

1993 • 86 citations

Synthesis, purification and initial structural characterization of octarellin, a de novo polypeptide modelled on the α/β-barrel Proteins

1990 • 85 citations

A differential scanning calorimetric study of the thermal unfolding of seven mutant forms of phage T4 lysozyme

1991 • 66 citations

Genetic and structural analysis of the ColE1 Rop (Rom) protein.

1989 • 59 citations

Regulation of plasmid copy number by complementary RNAs

1985 • 48 citations

ColE1-compatible vectors for high-level expression of cloned DNAs from the T7 promoter

1994 • 31 citations