A role for phospholipase C activity but not ryanodine receptors in the initiation and propagation of intercellular calcium waves

Glutamate Induces Calcium Waves in Cultured Astrocytes: Long-Range Glial Signaling

1990 • 1,820 citations

Neuronal activity triggers calcium waves in hippocampal astrocyte networks

1992 • 818 citations

Intercellular signaling in glial cells: Calcium waves and oscillations in response to mechanical stimulation and glutamate

1991 • 723 citations

Ryanodine activation and inhibition of the Ca2+ release channel of sarcoplasmic reticulum.

1986 • 710 citations

Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils.

1990 • 615 citations

Hepatocyte gap junctions are permeable to the second messenger, inositol 1,4,5-trisphosphate, and to calcium ions.

1989 • 596 citations

Receptor-coupled signal transduction in human polymorphonuclear neutrophils: effects of a novel inhibitor of phospholipase C-dependent processes on cell responsiveness.

1990 • 567 citations

Regulation of Phospholipase C-γ1 by Profilin and Tyrosine Phosphorylation

1991 • 532 citations

Intercellular Propagation of Calcium Waves Mediated by Inositol Trisphosphate

1992 • 518 citations

The aminosteroid U-73122 inhibits muscarinic receptor sequestration and phosphoinositide hydrolysis in SK-N-SH neuroblastoma cells. A role for Gp in receptor compartmentation.

1991 • 453 citations

The ryanodine receptor/Ca2+ release channel

1993 • 404 citations

Free calcium increases explosively in activating medaka eggs.

1977 • 367 citations

Mechanical stimulation and intercellular communication increases intracellular Ca2+ in epithelial cells.

1990 • 363 citations

Calcium waves in astrocytes-filling in the gaps

1992 • 321 citations

Intercellular calcium signaling via gap junctions in glioma cells.

1992 • 316 citations

Mechanisms and function of intercellular calcium signaling

1994 • 305 citations

U73122 inhibits Ca2+ oscillations in response to cholecystokinin and carbachol but not to JMV-180 in rat pancreatic acinar cells.

1992 • 302 citations

Expression of a Ryanodine Receptor-Ca ²⁺ Channel that is Regulated by TGF-β

1992 • 247 citations

Isolation, characterization, and localization of the inositol 1,4,5-trisphosphate receptor protein in Xenopus laevis oocytes.

1992 • 241 citations

Signal Transduction by P₂-Purinergic Receptors for Extracellular ATP

1991 • 193 citations

Intercellular calcium waves mediated by diffusion of inositol trisphosphate: a two-dimensional model

1995 • 183 citations

Mechanisms of intercellular calcium signaling in glial cells studied with dantrolene and thapsigargin

1993 • 163 citations

Classes and mechanisms of calcium waves

1993 • 162 citations

A model for the propagation of intercellular calcium waves

1994 • 151 citations

Glutamate‐induced calcium signaling in astrocytes

1994 • 146 citations

Mechanosensitive and Beta-Adrenergic Control of the Ciliary Beat Frequency of Mammalian Respiratory Tract Cells in Culture

1989 • 144 citations

Mechanosensitivity of cultured ciliated cells from the mammalian respiratory tract: implications for the regulation of mucociliary transport.

1986 • 140 citations

U73122 inhibits phospholipase C-dependent calcium mobilization in neuronal cells

1994 • 139 citations

U-73122, an aminosteroid phospholipase C antagonist, noncompetitively inhibits thyrotropin-releasing hormone effects in GH3 rat pituitary cells.

1992 • 128 citations

Intercellular calcium signaling induced by extracellular adenosine 5′-triphosphate and mechanical stimulation in airway epithelial cells

1993 • 127 citations

Control of the beat cycle of respiratory tract cilia by Ca2+ and cAMP

1992 • 127 citations

Phase-dependent contributions from Ca2+ entry and Ca2+ release to caffeine-induced [Ca2+]i oscillations in bullfrog sympathetic neurons

1992 • 125 citations

Effect of cAMP on ciliary function in rabbit tracheal epithelial cells

1989 • 85 citations

Intracellular calcium waves generated by ins(1,4,5)P3-dependent mechanisms

1993 • 83 citations

A role for Ca2+-conducting ion channels in mechanically-induced signal transduction of airway epithelial cells

1994 • 78 citations

Calcium waves

1993 • 76 citations

Intercellular Calcium Waves Mediated by Inositol Trisphosphate

2007 • 74 citations

Smooth muscle stretch-activated phospholipase C activity

1995 • 73 citations

Stretch-induced Inositol Trisphosphate and Tetrakisphosphate Production in Rat Cardiomyocytes

1993 • 68 citations

Stretch-sensitive ion channels: an update.

1992 • 64 citations

Spontaneous calcium oscillations and mechanically and chemically induced calcium responses in mammary epithelial cells

1993 • 61 citations

A versatile and quantitative computer‐assisted photoelectronic technique used for the analysis of ciliary beat cycles

1985 • 61 citations

Stretch increases inositol trisphosphate and inositol tetrakisphosphate in cultured pulmonary vascular smooth muscle cells

1991 • 59 citations

Phospholipase C: A Putative Mechanotransducer for Endothelial Cell Response to Acute Hemodynamic Changes

1993 • 58 citations

Regulation of Inositol 1,4,5-Trisphosphate Receptors

1993 • 49 citations

P1 and P2 purinergic receptor signal transduction in rat type II pneumocytes

1989 • 36 citations

Calcium waves, gradients and oscillations

1995 • 31 citations

Gonadotropin-releasing hormone-stimulated intracellular Ca2+ fluctuations and luteinizing hormone release can be uncoupled from inositol phosphate production.

1992 • 31 citations

Characterization of the Major Phosphoinositide-specific Phospholipase C of Human Amnion

1990 • 27 citations

Effect of Phospholipase C Inhibitor U-73122 on Antigen-induced Airway Smooth Muscle Contraction in Guinea Pigs

1993 • 15 citations

Activation of PtdIns(4,5)P2-sensitive phospholipase C in rabbit tracheal epithelial cells

1994 • 9 citations

Cultured porcine aortic endothelial gap-junctions-characterization and permeation by 2nd messenger molecules

1994 • 4 citations

Deleted Work

1955 • 0 citations