The aminosteroid U-73122 inhibits muscarinic receptor sequestration and phosphoinositide hydrolysis in SK-N-SH neuroblastoma cells. A role for Gp in receptor compartmentation.

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Regulation of Polyphosphoinositide-specific Phospholipase C Activity by Purified G _q

1991 • 886 citations

Activation of the β1 isozyme of phospholipase C by α subunits of the Gq class of G proteins

1991 • 774 citations

Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils.

1990 • 615 citations

Receptor-coupled signal transduction in human polymorphonuclear neutrophils: effects of a novel inhibitor of phospholipase C-dependent processes on cell responsiveness.

1990 • 567 citations

Protein determination by Lowry's method in the presence of sulfhydryl reagents

1972 • 244 citations

Biochemical differentiation of mechanically dissociated mammalian brain in aggregating cell culture

1976 • 187 citations

Mutations of the human beta 2-adrenergic receptor that impair coupling to Gs interfere with receptor down-regulation but not sequestration.

1991 • 136 citations

A human neuroblastoma cell line expresses mu and delta opioid receptor sites.

1986 • 126 citations

Differential receptor occupancy requirements for muscarinic cholinergic stimulation of inositol lipid hydrolysis in brain and in neuroblastomas.

1987 • 105 citations

Genetic analysis of beta-adrenergic receptor internalization and down-regulation.

1985 • 102 citations

Guanine nucleotide regulation of agonist binding to muscarinic cholinergic receptors. Relation to efficacy of agonists for stimulation of phosphoinositide breakdown and Ca2+ mobilization

1985 • 96 citations

A Putative M₃ Muscarinic Cholinergic Receptor of High Molecular Weight Couples to Phosphoinositide Hydrolysis in Human SK‐N‐SH Neuroblastoma Cells

1988 • 78 citations

Relationship between agonist-induced muscarinic receptor loss and desensitization of stimulated phosphoinositide turnover in two neuroblastomas: methodological considerations.

1990 • 69 citations

Separation of the structural requirements for agonist-promoted activation and sequestration of the beta-adrenergic receptor.

1990 • 64 citations

Muscarinic Receptor‐Stimulated Phosphoinositide Turnover in Human SK‐N‐SH Neuroblastoma Cells: Differential Inhibition by Agents that Elevate Cyclic AMP

1989 • 33 citations

Recognition of muscarinic cholinergic receptors in human SK-N-SH neuroblastoma cells by quaternary and tertiary ligands is dependent upon temperature, cell integrity, and the presence of agonists.

1988 • 33 citations

Polyphosphoinositides are the major source of inositol phosphates in carbamoylcholine-stimulated SK-N-SH neuroblastoma cells.

1990 • 27 citations

Compartmentation of alpha 2-adrenergic receptors in human erythroleukemia (HEL) cells.

1987 • 25 citations

Preferential coupling of cell surface muscarinic receptors to phosphoinositide hydrolysis in human neuroblastoma cells.

1991 • 19 citations