Phase IIa Clinical Trial of Curcumin for the Prevention of Colorectal Neoplasia

Bioavailability of Curcumin: Problems and Promises

2007 • 4,820 citations

Dose escalation of a curcuminoid formulation

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Phase II Trial of Curcumin in Patients with Advanced Pancreatic Cancer

2008 • 1,243 citations

Phase I Clinical Trial of Oral Curcumin

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Chemoprevention of colon carcinogenesis by dietary curcumin, a naturally occurring plant phenolic compound.

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Pharmacology of diferuloyl methane (curcumin), a non-steroidal anti-inflammatory agent

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Curcumin Maintenance Therapy for Ulcerative Colitis: Randomized, Multicenter, Double-Blind, Placebo-Controlled Trial

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Aberrant Crypt Foci of the Colon as Precursors of Adenoma and Cancer

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Inhibitory effects of curcumin on in vitro lipoxygenase and cyclooxygenase activities in mouse epidermis.

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Inhibitory effects of dietary curcumin on forestomach, duodenal, and colon carcinogenesis in mice.

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Pharmacokinetics of Curcumin Conjugate Metabolites in Healthy Human Subjects

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Targeting breast stem cells with the cancer preventive compounds curcumin and piperine

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Consumption of the Putative Chemopreventive Agent Curcumin by Cancer Patients: Assessment of Curcumin Levels in the Colorectum and their Pharmacodynamic Consequences

2005 • 471 citations

Combination Treatment With Curcumin and Quercetin of Adenomas in Familial Adenomatous Polyposis

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Enhancement of oral absorption of curcumin by self-microemulsifying drug delivery systems

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Role of the prostaglandin E receptor subtype EP1 in colon carcinogenesis.

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Comparison of systemic availability of curcumin with that of curcumin formulated with phosphatidylcholine

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Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine

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Anti-inflammatory and irritant activities of curcumin analogues in rats

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Correlation of DNA adduct levels in human lung with cigarette smoking

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Aberrant crypts: potential preneoplastic lesions in the murine colon.

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Metformin Suppresses Colorectal Aberrant Crypt Foci in a Short-term Clinical Trial

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Retracted: Notch‐1 down‐regulation by curcumin is associated with the inhibition of cell growth and the induction of apoptosis in pancreatic cancer cells

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Most Effective Colon Cancer Chemopreventive Agents in Rats: A Systematic Review of Aberrant Crypt Foci and Tumor Data, Ranked by Potency

2002 • 228 citations

The Chemopreventive Polyphenol Curcumin Prevents Hematogenous Breast Cancer Metastases in Immunodeficient Mice

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Curcumin enhances the effects of 5‐fluorouracil and oxaliplatin in mediating growth inhibition of colon cancer cells by modulating EGFR and IGF‐1R

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Analysis of DNA and protein adducts of benzo[a]pyrene in human tissues using structure-specific methods

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Curcumin Modulates the Radiosensitivity of Colorectal Cancer Cells by Suppressing Constitutive and Inducible NF-κB Activity

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Foci of aberrant crypts in the colons of mice and rats exposed to carcinogens associated with foods.

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Why Do African Americans Get More Colon Cancer than Native Africans?

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Curcumin in plasma and urine: quantitation by high-performance liquid chromatography

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Injectable Sustained Release Microparticles of Curcumin: A New Concept for Cancer Chemoprevention

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Systemic Delivery of Curcumin: 21st Century Solutions for an Ancient Conundrum

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Suppression of Human Colorectal Mucosal Prostaglandins: Determining the Lowest Effective Aspirin Dose

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Diet, aberrant crypt foci and colorectal cancer

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Rapid Analysis of Curcumin and Curcumin Metabolites in Rat Biomatrices Using a Novel Ultraperformance Liquid Chromatography (UPLC) Method

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Tumor suppressor functions for the Cdk inhibitor p21 in the mouse colon

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Tobacco smoke induces CYP1B1 in the aerodigestive tract

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Prognostic effect of activated EGFR expression in human colon carcinomas: comparison with EGFR status

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Determination of endogenous tissue inflammation profiles by LC/MS/MS: COX- and LOX-derived bioactive lipids

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Curcumin induces apoptosis in HCT-116 human colon cancer cells in a p21-independent manner

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High levels of DNA adducts in human colon are associated with colorectal cancer.

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Endoscopic identification and quantification of aberrant crypt foci in the human colon

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Cell Proliferation and Apoptotic Indices Predict Adenoma Regression in a Placebo-Controlled Trial of Celecoxib in Familial Adenomatous Polyposis Patients

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Profiling Lipoxygenase Metabolism in Specific Steps of Colorectal Tumorigenesis

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Epidermal Growth Factor Receptor Controls Flat Dysplastic Aberrant Crypt Foci Development and Colon Cancer Progression in the Rat Azoxymethane Model

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Nuclear Morphometry and Molecular Biomarkers of Actinic Keratosis, Sun-Damaged, and Nonexposed Skin

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Assessment of Rectal Aberrant Crypt Foci by Standard Chromoscopy and its Predictive Value for Colonic Advanced Neoplasms

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A Multicenter Study of Prevalence and Risk Factors for Aberrant Crypt Foci

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Metabolism of curcumin and induction of mitotic catastrophe in human cancer cells

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Novel methoxylated flavone inhibitors of cytochrome P450 1B1 in SCC-9 human oral cancer cells

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Colon cancer chemoprevention by a novel NO chimera that shows anti-inflammatory and antiproliferative activity in vitro and in vivo

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Relationship of aging and tobacco use with the development of aberrant crypt foci in a predominantly African-American population

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Colonic mucosal prostaglandin E2 and cyclooxygenase expression before and after low aspirin doses in subjects at high risk or at normal risk for colorectal cancer.

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Curcumin Decreases Acid Sphingomyelinase Activity in Colon Cancer Caco-2 Cells

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Aberrant crypt foci: endoscopic assessment and cell kinetics characterization

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Colon Preparation for Magnification Endoscopy: a Rapid Novel Approach

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Reduced susceptibility to azoxymethane-induced aberrant crypt foci formation and colon cancer in growth hormone deficient rats

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