Cloning and Characterization of the Guinea Pig Eosinophil Eotaxin Receptor, C-C Chemokine Receptor-3: Blockade Using a Monoclonal Antibody In Vivo

Chemokines — Chemotactic Cytokines That Mediate Inflammation

1998 • 3,660 citations

Chemokines and leukocyte traffic

1998 • 2,755 citations

Eosinophilic Inflammation in Asthma

1990 • 2,535 citations

The β-Chemokine Receptors CCR3 and CCR5 Facilitate Infection by Primary HIV-1 Isolates

1996 • 2,326 citations

Differential Expression of Chemokine Receptors and Chemotactic Responsiveness of Type 1 T Helper Cells (Th1s) and Th2s

1998 • 2,048 citations

Chemokines

1997 • 1,926 citations

Flexible Programs of Chemokine Receptor Expression on Human Polarized T Helper 1 and 2 Lymphocytes

1998 • 1,574 citations

Selective Expression of the Eotaxin Receptor CCR3 by Human T Helper 2 Cells

1997 • 1,073 citations

Bronchoalveolar eosinophilia during allergen-induced late asthmatic reactions.

1985 • 1,065 citations

Dynamical Instabilities and the Formation of Extrasolar Planetary Systems

1996 • 1,000 citations

CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia

1997 • 923 citations

Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation.

1994 • 822 citations

Cloning of the human eosinophil chemoattractant, eotaxin. Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils.

1996 • 719 citations

Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia

1996 • 698 citations

Eosinophils, T-lymphocytes, mast cells, neutrophils, and macrophages in bronchial biopsy specimens from atopic subjects with asthma: Comparison with biopsy specimens from atopic subjects without asthma and normal control subjects and relationship to bronchial hyperresponsiveness

1991 • 681 citations

The chemotactic receptor for human C5a anaphylatoxin

1991 • 660 citations

Cooperation between interleukin-5 and the chemokine eotaxin to induce eosinophil accumulation in vivo.

1995 • 657 citations

Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils.

1996 • 626 citations

RANTES and macrophage inflammatory protein 1 alpha induce the migration and activation of normal human eosinophil granulocytes.

1992 • 620 citations

Cloning, expression, and characterization of the human eosinophil eotaxin receptor.

1996 • 561 citations

Targeted Disruption of the Chemokine Eotaxin Partially Reduces Antigen-induced Tissue Eosinophilia

1997 • 537 citations

Protein kinases that phosphorylate activated G protein‐coupled receptors

1995 • 520 citations

Chemokine receptor usage by human eosinophils. The importance of CCR3 demonstrated using an antagonistic monoclonal antibody.

1997 • 474 citations

Enhanced expression of eotaxin and CCR3 mRNA and protein in atopic asthma. Association with airway hyperresponsiveness and predominant co‐localization of eotaxin mRNA to bronchial epithelial and endothelial cells

1997 • 429 citations

Increased expression of eotaxin in bronchoalveolar lavage and airways of asthmatics contributes to the chemotaxis of eosinophils to the site of inflammation.

1997 • 419 citations

Eotaxin-2, a Novel CC Chemokine that Is Selective for the Chemokine Receptor CCR3, and Acts Like Eotaxin on Human Eosinophil and Basophil Leukocytes

1997 • 413 citations

Murine eotaxin: an eosinophil chemoattractant inducible in endothelial cells and in interleukin 4-induced tumor suppression.

1995 • 351 citations

Chemokine receptors: Structure, function and role in microbial pathogenesis

1996 • 329 citations

Human monocyte chemoattractant protein (MCP)-4 is a novel CC chemokine with activities on monocytes, eosinophils, and basophils induced in allergic and nonallergic inflammation that signals through the CC chemokine receptors (CCR)-2 and -3.

1996 • 314 citations

Functional expression of the eotaxin receptor CCR3 in T lymphocytes co-localizing with eosinophils

1997 • 292 citations

Eotaxin Induces a Rapid Release of Eosinophils and Their Progenitors From the Bone Marrow

1998 • 283 citations

Mouse Eotaxin Expression Parallels Eosinophil Accumulation during Lung Allergic Inflammation but It Is Not Restricted to a Th2-Type Response

1996 • 260 citations

Kinetics of Eotaxin Generation and Its Relationship to Eosinophil Accumulation in Allergic Airways Disease: Analysis in a Guinea Pig Model In Vivo

1997 • 255 citations

Costimulation of T Cell Activation by Integrin-associated Protein (CD47) Is an Adhesion-dependent, CD28-independent Signaling Pathway

1997 • 236 citations

The Chemokine, Eotaxin, Activates Guinea-Pig Eosinophils in Vitro and Causes Their Accumulation into the Lung in Vivo

1993 • 220 citations

Constitutive and allergen-induced expression of eotaxin mRNA in the guinea pig lung.

1995 • 204 citations

Cross-desensitization of receptors for peptide chemoattractants. Characterization of a new form of leukocyte regulation.

1994 • 174 citations

Chemokine-induced eosinophil recruitment. Evidence of a role for endogenous eotaxin in an in vivo allergy model in mouse skin.

1997 • 173 citations

Cloning and functional characterization of a novel human CC chemokine that binds to the CCR3 receptor and activates human eosinophils

1997 • 163 citations

Pulmonary immune cells in health and disease: the eosinophil leucocyte (Part II)

1994 • 161 citations

Eotaxin: Cloning of an Eosinophil Chemoattractant Cytokine and Increased mRNA Expression in Allergen-Challenged Guinea-Pig Lungs

1994 • 156 citations

Proton NMR Assignments and Solution Conformation of RANTES, a Chemokine of the C-C Type

1995 • 141 citations

Eotaxin Expression and Eosinophilic Inflammation in Asthma

1997 • 136 citations

The pro-inflammatory seven-transmembrane segment receptors of the leukocyte

1994 • 119 citations

Phosphorylation of the N-Formyl Peptide Receptor Carboxyl Terminus by the G Protein-coupled Receptor Kinase, GRK2

1995 • 108 citations

Discrete Steps in Binding and Signaling of Interleukin-8 with Its Receptor

1996 • 106 citations

Chemoattractant cross-desensitization of the human neutrophil IL-8 receptor involves receptor internalization and differential receptor subtype regulation.

1997 • 106 citations

Molecular characterization of two murine eosinophil beta chemokine receptors.

1995 • 102 citations

The accumulation of 111In-eosinophils induced by inflammatory mediators, in vivo.

1991 • 92 citations

Contrasting responses to multiple chemotactic stimuli in transendothelial migration: heterologous desensitization in neutrophils and augmentation of migration in eosinophils.

1997 • 87 citations

Identification of a Mouse Eosinophil Receptor for the CC Chemokine Eotaxin

1996 • 86 citations

Cloning and characterization of human chemokine receptors

1996 • 68 citations

Eotaxin Induces a Rapid Release of Eosinophils and Their Progenitors From the Bone Marrow

1998 • 68 citations

Chemokine Receptor CCR3 Function Is Highly Dependent on Local pH and Ionic Strength

1997 • 56 citations

Chemokines Take Center Stage in Inflammatory Ills

1996 • 53 citations

Recombinant guinea pig and human RANTES activate macrophages but not eosinophils in the guinea pig.

1997 • 41 citations

Evidence that a receptor-operated event on the neutrophil mediates neutrophil accumulation in vivo. Pretreatment of 111In-neutrophils with pertussis toxin in vitro inhibits their accumulation in vivo.

1990 • 41 citations

Conserved structure and tissue expression of rat eotaxin

1997 • 26 citations

Human RANTES acts as a receptor antagonist for guinea pig eotaxin in vitro and in vivo.

1996 • 19 citations