Multiple T helper cell epitopes of the circumsporozoite protein of Plasmodium berghei

Synthetic peptide vaccine design: synthesis and properties of a high-density multiple antigenic peptide system.

1988 • 1,241 citations

γ Interferon, CD8+ T cells and antibodies required for immunity to malaria sporozoites

1987 • 699 citations

Safety and immunogenicity in man of a synthetic peptide malaria vaccine against Plasmodium falciparum sporozoites

1987 • 512 citations

CD8+ T cells (cytotoxic/suppressors) are required for protection in mice immunized with malaria sporozoites.

1988 • 477 citations

Monovalent fragments (Fab) of monoclonal antibodies to a sporozoite surface antigen (Pb44) protect mice against malarial infection.

1980 • 439 citations

SAFETY AND EFFICACY OF A RECOMBINANT DNA PLASMODIUM FALCIPARUM SPOROZOITE VACCINE

1987 • 428 citations

Carrier-induced epitopic suppression, a major issue for future synthetic vaccines.

1985 • 298 citations

Mechanisms for the removal of benzyl protecting groups in synthetic peptides by trifluoromethanesulfonic acid-trifluoroacetic acid-dimethyl sulfide

1986 • 281 citations

Circumsporozoite proteins of human malaria parasites Plasmodium falciparum and Plasmodium vivax.

1982 • 280 citations

Construction of Synthetic Immunogen: Use of New T-Helper Epitope on Malaria Circumsporozoite Protein

1987 • 270 citations

Human T-cell recognition of the circumsporozoite protein of Plasmodium falciparum: immunodominant T-cell domains map to the polymorphic regions of the molecule.

1988 • 264 citations

tert-Butoxycarbonylaminoacyl-4-(oxymethyl)phenylacetamidomethyl-resin, a more acid-resistant support for solid-phase peptide synthesis

1976 • 252 citations

Synthetic peptide vaccine confers protection against murine malaria.

1987 • 232 citations

Circumsporozoite protein of Plasmodium berghei: gene cloning and identification of the immunodominant epitopes.

1986 • 198 citations

Epitope-specific regulation. I. Carrier-specific induction of suppression for IgG anti-hapten antibody responses

1982 • 143 citations

Immunity to sporozoite-induced malaria infeciton in mice. I. The effect of immunization of T and B cell-deficient mice.

1977 • 109 citations

Immunity to Sporozoite-Induced Malaria Infection in Mice

1977 • 76 citations

Epitopes recognized by human t lymphocytes on malaria circumsporozoite protein

1988 • 74 citations

Expression in yeast of a Plasmodium vivax antigen of potential use in a human malaria vaccine.

1987 • 66 citations

Effect of carrier on the immunogenic capacity of synthetic cholera vaccine

1985 • 54 citations

Epitopic suppression in synthetic vaccine models: Analysis of the effector mechanisms

1987 • 45 citations

Immunoprophylaxis of malaria: characterization of a protective surface antigen.

1982 • 4 citations