alpha-2 Adrenergic Receptors

A STUDY OF THE ADRENOTROPIC RECEPTORS

1948 • 2,856 citations

Differentiation of Receptor Systems activated by Sympathomimetic Amines

1967 • 2,054 citations

Presynaptic regulation of catecholamine release

1974 • 1,145 citations

SIXTH GADDUM MEMORIAL LECTURE NATIONAL INSTITUTE FOR MEDICAL RESEARCH, MILL HILL, JANUARY 1977

1977 • 935 citations

A functional basis for classification of α-adrenergic receptors

1977 • 802 citations

ADENYL CYCLASE AS AN ADRENERGIC RECEPTOR*

1967 • 682 citations

PRESYNAPTIC RECEPTORS AND THEIR ROLE IN THE REGULATION OF TRANSMITTER RELEASE.

1977 • 616 citations

Evidence for a central noradrenaline receptor stimulation by clonidine

1970 • 550 citations

Binding characteristics of a radiolabeled agonist and antagonist at central nervous system alpha noradrenergic receptors.

1977 • 544 citations

α ₂ -Adrenergic Mechanisms in Prefrontal Cortex Associated with Cognitive Decline in Aged Nonhuman Primates

1985 • 544 citations

Characterization of alpha 1-adrenergic receptor subtypes in rat brain: a reevaluation of [3H]WB4104 and [3H]prazosin binding.

1986 • 456 citations

The output of sympathetic transmitter from the spleen of the cat

1957 • 405 citations

Comparison of the effects of clonidine on pre-and postsynaptic adrenoceptors in the rabbit pulmonary artery

1974 • 316 citations

Radioligand Binding Studies of Adrenergic Receptors: New Insights into Molecular and Physiological Regulation

1980 • 313 citations

Role of phosphatidylinositol turnover in alpha1 and of adenylate cyclase inhibition in alpha2 effects of catecholamines

1980 • 298 citations

Alpha-noradrenergic receptor binding in mammalian brain: Differential labeling of agonist and antagonist states

1976 • 298 citations

Heterogeneity of alpha-2 adrenergic receptors

1985 • 297 citations

Regulation of adenylate cyclase of neuroblastoma x glioma hybrid cells by alpha-adrenergic receptors. I. Inhibition of adenylate cyclase mediated by alpha receptors.

1979 • 288 citations

An adrenergic receptor mechanism for the control of cyclic 3′5′ adenosine monophosphate synthesis in tissues

1967 • 285 citations

Alpha-adrenergic receptor subtypes: Quantitative assessment by ligand binding

1979 • 264 citations

Comparison of beta adrenergic receptor subtypes in mammalian tissues.

1979 • 245 citations

Characterization of α1-and α2-Adrenergic Receptors

1983 • 230 citations

Role of the α‐adrenoceptor in regulating noradrenaline overflow by nerve stimulation

1972 • 216 citations

Negative feedback regulation of noradrenaline release by nerve stimulation in the perfused cat's spleen: differences in potency of phenoxybenzamine in blocking the pre‐ and post‐synaptic adrenergic receptors

1974 • 198 citations

Drug‐induced changes in the release of [³H]‐noradrenaline from field stimulated rat iris

1971 • 186 citations

The metabolism of [³H]noradrenaline released by electrical stimulation from the isolated nictitating membrane of the cat and from the vas deferens of the rat

1970 • 182 citations

Characterization of α2-adrenergic receptors on human platelets using [3H]yohimbine

1980 • 166 citations

Inhibitors of Na+/H+ exchange block stimulus-provoked arachidonic acid release in human platelets. Selective effects on platelet activation by epinephrine, ADP, and lower concentrations of thrombin.

1985 • 144 citations

The pharmacological classification of adrenergic alpha 1 and alpha 2 receptors and their mechanisms of action.

1979 • 143 citations

Effect of flow‐stop on noradrenaline release from normal spleens and spleens treated with cocaine, phentolamine or phenoxybenzamine

1971 • 135 citations

Alpha-Adrenergic Receptor Identification by [ ³ H]Dihydroergocryptine Binding

1976 • 130 citations

Different types of sympathomimetic α-receptors

1965 • 129 citations

Direct biochemical demonstration of two types of α-adrenoreceptor in rat brain

1978 • 122 citations

Pharmacology of Cholinergic and Adrenergic Transmission

1965 • 114 citations

New Aspects of Storage and Release Mechanisms of Catecholamines

1970 • 111 citations

Influence of ?-receptor stimulants on noradrenaline release

1971 • 104 citations

Epinephrine in the central nervous system

1988 • 102 citations

A further attempt to characterize sedative receptors activated by clonidine in chickens and mice

1973 • 82 citations

Enhanced Release of Dopamine-β-Hydroxylase from Sympathetic Nerves by Calcium and Phenoxybenzamine and Its Reversal by Prostaglandins

1971 • 81 citations

Stimulus-Response Coupling at α-Adrenergic Receptors

1978 • 78 citations

Lipolysis by human adipose tissue: the role of cyclic 3',5'-adenosine monophosphate and adrenergic receptor sites.

1970 • 76 citations

Pharmacological properties of (3H) dihydroergokryptine binding sites associated with alpha noradrenergic receptors in rat brain membranes.

1978 • 66 citations

α-Adrenoceptor-effector coupling: affinity states or heterogeneity of the α2-adrenoceptor?

1985 • 61 citations

Release of noradrenaline and dopamine by nerve stimulation in the cat spleen perfused with ³H‐dopamine

1971 • 57 citations

Alterations in central and peripheral adrenergic receptors in deoxycorticosterone/salt hypertensive rats

1980 • 56 citations

Facilitation of the release of noradrenaline and dopamine- -hydroxylase at low stimulation frequencies by -blocking agents.

1971 • 52 citations

Regional variations in alpha adrenergic receptor interactions of [3H]-dihydroergokryptine in calf brain: implications for a two-site model of alpha receptor function.

1978 • 52 citations

Some Further Aspects on the Release of the Adrenergic Transmitter

1970 • 50 citations

Alpha 2-adrenergic receptor-mediated sensitization of forskolin-stimulated cyclic AMP production.

1987 • 40 citations

ADENYL CYCLASE AND HORMONE ACTION

1965 • 19 citations

Output of Sympathin from the Spleen

1956 • 17 citations

α2-Adrenergic Receptors: Apparent Interaction with Multiple Effector Systems

1985 • 14 citations