The Orphan Nuclear Receptor SHP Inhibits Hepatocyte Nuclear Factor 4 and Retinoid X Receptor Transactivation: Two Mechanisms for Repression

The nuclear receptor superfamily: The second decade

1995 • 6,929 citations

The RXR heterodimers and orphan receptors

1995 • 3,168 citations

The Transcriptional Coactivators p300 and CBP Are Histone Acetyltransferases

1996 • 2,873 citations

The Structural Basis of Estrogen Receptor/Coactivator Recognition and the Antagonism of This Interaction by Tamoxifen

1998 • 2,622 citations

Sequence and Characterization of a Coactivator for the Steroid Hormone Receptor Superfamily

1995 • 2,390 citations

A CBP Integrator Complex Mediates Transcriptional Activation and AP-1 Inhibition by Nuclear Receptors

1996 • 2,183 citations

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ

1998 • 1,902 citations

The CBP co-activator is a histone acetyltransferase

1996 • 1,773 citations

AIB1, a Steroid Receptor Coactivator Amplified in Breast and Ovarian Cancer

1997 • 1,655 citations

Mutations in the hepatocyte nuclear factor-1α gene in maturity-onset diabetes of the young (MODY3)

1996 • 1,607 citations

Nuclear Receptor Coactivator ACTR Is a Novel Histone Acetyltransferase and Forms a Multimeric Activation Complex with P/CAF and CBP/p300

1997 • 1,472 citations

A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

1996 • 1,457 citations

The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function

1997 • 1,300 citations

Steroid receptor coactivator-1 is a histone acetyltransferase

1997 • 1,245 citations

TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors.

1996 • 1,095 citations

Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid

1995 • 1,085 citations

Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily.

1990 • 1,044 citations

Mutations in the hepatocyte nuclear factor-4α gene in maturity-onset diabetes of the young (MODY1)

1996 • 941 citations

A structural role for hormone in the thyroid hormone receptor

1995 • 938 citations

Structure and specificity of nuclear receptor–coactivator interactions

1998 • 922 citations

Nuclear receptor coactivators and corepressors.

1996 • 917 citations

Coactivator and corepressor complexes in nuclear receptor function

1999 • 909 citations

An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita

1994 • 857 citations

Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors.

1992 • 829 citations

Unique response pathways are established by allosteric interactions among nuclear hormone receptors

1995 • 629 citations

RAC3, a steroid/nuclear receptor-associated coactivator that is related to SRC-1 and TIF2

1997 • 585 citations

GRIP1, a Transcriptional Coactivator for the AF-2 Transactivation Domain of Steroid, Thyroid, Retinoid, and Vitamin D Receptors

1997 • 572 citations

A Smad Transcriptional Corepressor

1999 • 563 citations

An Orphan Nuclear Hormone Receptor That Lacks a DNA Binding Domain and Heterodimerizes with Other Receptors

1996 • 535 citations

Role of co-activators and co-repressors in the mechanism of steroid/thyroid receptor action.

1997 • 534 citations

DAX-1 Inhibits SF-1-Mediated Transactivation via a Carboxy-Terminal Domain That Is Deleted in Adrenal Hypoplasia Congenita

1997 • 469 citations

The Angelman Syndrome-Associated Protein, E6-AP, Is a Coactivator for the Nuclear Hormone Receptor Superfamily

1999 • 444 citations

The histone acetylase PCAF is a nuclear receptor coactivator

1998 • 389 citations

TRAM-1, A Novel 160-kDa Thyroid Hormone Receptor Activator Molecule, Exhibits Distinct Properties from Steroid Receptor Coactivator-1

1997 • 380 citations

Orphan nuclear receptors--the first eight years.

1996 • 206 citations

A Transcriptional Silencing Domain in DAX-1 Whose Mutation Causes Adrenal Hypoplasia Congenita

1997 • 186 citations

The Orphan Nuclear Receptor SHP Inhibits Agonist-dependent Transcriptional Activity of Estrogen Receptors ERα and ERβ

1999 • 179 citations

Two receptor interacting domains in the nuclear hormone receptor corepressor RIP13/N-CoR.

1996 • 159 citations

Clinical and Functional Effects of Mutations in theDAX-1Gene in Patients with Adrenal Hypoplasia Congenita¹

1999 • 153 citations

SRC-1 and GRIP1 Coactivate Transcription with Hepatocyte Nuclear Factor 4

1998 • 146 citations

Functional Domains of the Nuclear Receptor Hepatocyte Nuclear Factor 4

1997 • 144 citations

The directly repeated RG(G/T)TCA motifs of the rat and mouse cellular retinol-binding protein II genes are promiscuous binding sites for RAR, RXR, HNF-4, and ARP-1 homo- and heterodimers.

1994 • 142 citations

Inhibition of Estrogen Receptor Action by the Orphan Receptor SHP (Short Heterodimer Partner)

1998 • 139 citations

Novel Receptor Interaction and Repression Domains in the Orphan Receptor SHP

1997 • 133 citations

Activation of RNA polymerase II transcription

1999 • 106 citations

Activation of the Promoter of the Orphan Receptor SHP by Orphan Receptors That Bind DNA as Monomers

1999 • 103 citations

Mouse Retinoid X Receptor Contains a Separable Ligand-Binding and Transactivation Domain in Its E Region

1995 • 95 citations

DAX1 Mutations Map to Putative Structural Domains in a Deduced Three-Dimensional Model

1998 • 94 citations

CREB-binding Protein Is a Transcriptional Coactivator for Hepatocyte Nuclear Factor-4 and Enhances Apolipoprotein Gene Expression

1999 • 88 citations

Activation of the orphan receptor RIP14 by retinoids

1997 • 87 citations

Mutations that alter ligand-induced switches and dimerization activities in the retinoid X receptor.

1994 • 77 citations

Proposed Mechanism for the Stabilization of Nuclear Receptor DNA Binding via Protein Dimerization

1997 • 27 citations

Mutations That Alter Ligand-induced Switches and Dimerization Activities in the Retinoid X Receptor

1994 • 21 citations