Supportive cellular elements for hepatic T cell differentiation: T cells expressing intermediate levels of the T cell receptor are cytotoxic against syngeneic hepatoma, and are lost after hepatocyte damage

Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications

1994 • 1,752 citations

Two gut intraepithelial CD8+ lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation.

1991 • 599 citations

The V beta repertoire of mouse gut homodimeric alpha CD8+ intraepithelial T cell receptor alpha/beta + lymphocytes reveals a major extrathymic pathway of T cell differentiation.

1991 • 345 citations

Major histocompatibility complex class I related molecules control the development of CD4+8- and CD4-8- subsets of natural killer 1.1+ T cell receptor-alpha/beta+ cells in the liver of mice.

1994 • 304 citations

Thymus-independent development and negative selection of T cells expressing T cell receptor alpha/beta in the intestinal epithelium: evidence for distinct circulation patterns of gut- and thymus-derived T lymphocytes.

1992 • 268 citations

Extrathymic origin of intestinal intraepithelial lymphocytes bearing T-cell antigen receptor gamma delta.

1991 • 262 citations

Oligoclonal Expansion and CD1 Recognition by Human Intestinal Intraepithelial Lymphocytes

1991 • 243 citations

Developmentally regulated expression of T cell receptor beta chain variable domains in immature thymocytes.

1987 • 230 citations

Cytotoxic NK1.1 Ag+ alpha beta T cells with intermediate TCR induced in the liver of mice by IL-12.

1995 • 222 citations

Requirement of donor-derived stromal cells in the bone marrow for successful allogeneic bone marrow transplantation. Complete prevention of recurrence of autoimmune diseases in MRL/MP-Ipr/Ipr mice by transplantation of bone marrow plus bones (stromal cells) from the same donor.

1994 • 197 citations

Cytotoxic differentiation of mouse gut thymodependent and independent intraepithelial T lymphocytes is induced locally. Correlation between functional assays, presence of perforin and granzyme transcripts, and cytoplasmic granules.

1991 • 183 citations

Liver is a possible site for the proliferation of abnormal CD3+4-8- double-negative lymphocytes in autoimmune MRL-lpr/lpr mice.

1990 • 173 citations

Details of an isolation method for hepatic lymphocytes in mice

1992 • 169 citations

Differentiation potential of subsets of CD4−8− thymocytes

1987 • 169 citations

Estrogen administration activates extrathymic T cell differentiation in the liver.

1992 • 153 citations

Isolation and flow cytometric analysis of the free lymphomyeloid cells present in murine liver

1990 • 148 citations

The appearance of T cells bearing self-reactive T cell receptor in the livers of mice injected with bacteria.

1991 • 145 citations

Extrathymic development of V alpha 14-positive T cells.

1993 • 132 citations

Unusual alpha beta-T cells expanded in autoimmune lpr mice are probably a counterpart of normal T cells in the liver.

1991 • 124 citations

Kinetic analysis of cytokine gene expression in the livers of naive and immune mice infected with Listeria monocytogenes. The immediate early phase in innate resistance and acquired immunity.

1992 • 113 citations

Highly restricted expression of the thymus leukemia antigens on intestinal epithelial cells.

1991 • 112 citations

Ontogeny and development of extrathymic T cells in mouse liver.

1992 • 100 citations

Studies of CD4- CD8- alpha beta bone marrow T cells with suppressor activity.

1992 • 82 citations

Stimulation of lamina propria lymphocytes by intestinal epithelial cells: evidence for recognition of nonclassical restriction elements.

1994 • 75 citations

Similarities and Differences between Extrathymic T Cells Residing in Mouse Liver and Intestine

1994 • 71 citations

Extrathymic Pathways of T-cell Differentiation in the Liver and Other Organs

1994 • 68 citations

T cell lineages in the thymus of lpr/lpr mice. Evidence for parallel pathways of normal and abnormal T cell development.

1987 • 66 citations

Synchronous Expansion of Intermediate TCR Cells in the Liver and Uterus during Pregnancy

1995 • 66 citations

Evidence for extrathymic development of TNK cells. NK1+ CD3+ cells responsible for acute marrow graft rejection are present in thymus-deficient mice.

1992 • 64 citations

Differentiation of dendritic cell populations in macrophage colony-stimulating factor-deficient mice homozygous for the osteopetrosis (op) mutation

1993 • 61 citations

Expression of an unusual T cell receptor (TCR)-V beta repertoire by Ly-6C+ subpopulations of CD4+ and/or CD8+ thymocytes. Evidence for a developmental relationship between Ly-6C+ thymocytes and CD4-CD8-TCR-alpha beta+ thymocytes.

1991 • 59 citations

T cell antigen receptor expression by subsets of Ly-2-L3T4- (CD8-CD4-) thymocytes.

1988 • 51 citations

Intrathymic selection of murine TCRαβ⁺CD4⁻CD8⁻ thymocytes

1990 • 50 citations

Maturational arrest from CD4+8+ to CD4+8- thymocytes in a mutant strain (LEC) of rat.

1990 • 49 citations

Origin, differentiation, and repertoire selection of CD3+CD4-CD8- thymocytes bearing either alpha beta or gamma delta T cell receptors.

1993 • 48 citations

Distinctive selection mechanisms govern the T cell receptor repertoire of peripheral CD4-CD8- alpha/beta T cells.

1992 • 43 citations

Development of autoreactive L3T4⁺ T cells from double‐negative (L3T4⁻/Ly‐2⁻) Thy‐1⁺ spleen cells of normal mice

1988 • 37 citations

Immunolocalization of heparinbinding growth factors (HBGF) types 1 and 2 in rat liver. Selective hyperexpression of HBGF‐2 in carbon tetrachloride‐induced fibrosis

1993 • 29 citations

Unique Order of the Lymphocyte Subset Induction in the Liver and Intestine of Mice during Listeria monocytogenes Infection

1995 • 27 citations

V beta repertoire of murine hepatic T cells. Implication for selection of double negative alpha beta + T cells.

1994 • 24 citations

The Liver and the Hematolymphoid System: I. The Regulation of Nylon-Passed Spleen Cell Proliferation by Active Factors Released From Syngeneic Nonparenchymal Liver Cells

1991 • 21 citations

High prevalence of hepatitis B and C viral markers in Japanese patients with hepatocellular carcinoma

1993 • 8 citations

<b>SITE OF EXTRATHYMIC T-CELL PROLIFERATION AND THEIR SUBSEQUENT FATE, OCCURRING IN THE LIVER OF AUTOIMMUNE MRL-<i>1pr</i>/<i>1pr </i></b><b>MICE </b>

1994 • 6 citations

Autopsy case of hepatocellular carcinoma associated with lupoid hepatitis and complicated by malignant lymphoma

1993 • 3 citations

<b>PROFOUND SUPPRESSION OF THE DIFFERENTIATION AND FUNCTIONS OF INTERMEDIATE TCR CELLS IN THE LIVER OF MICE WITH LIVER INJURY INDUCED BY CARBON </b><b>TETRACHLORIDE </b>

1994 • 2 citations