Molecular Analysis of Protein Assembly in Muscle Development

Principles that Govern the Folding of Protein Chains

1973 • 6,771 citations

The Nematode Caenorhabditis elegans

1988 • 2,868 citations

The Immunoglobulin Superfamily—Domains for Cell Surface Recognition

1988 • 2,237 citations

ATPase Activity of Myosin Correlated with Speed of Muscle Shortening

1967 • 1,969 citations

Atomic structure of the actin: DNase I complex

1990 • 1,897 citations

Atomic model of the actin filament

1990 • 1,657 citations

Electron microscope studies on the structure of natural and synthetic protein filaments from striated muscle

1963 • 1,452 citations

A molecular basis for familial hypertrophic cardiomyopathy: A β cardiac myosin heavy chain gene missense mutation

1990 • 1,332 citations

Interaction of plasma membrane fibronectin receptor with talin—a transmembrane linkage

1986 • 1,206 citations

Neural Cell Adhesion Molecule: Structure, Immunoglobulin-Like Domains, Cell Surface Modulation, and Alternative RNA Splicing

1987 • 1,134 citations

Cell Surface Receptors for Extracellular Matrix Molecules

1987 • 793 citations

A theory of linear and helical aggregations of macromolecules

1962 • 746 citations

Invited review: Neural control of phenotypic expression in mammalian muscle fibers

1985 • 734 citations

Actin Antibody: The Specific Visualization of Actin Filaments in Non-Muscle Cells

1974 • 721 citations

α‐Helical coiled coils and bundles: How to design an α‐helical protein

1990 • 720 citations

Primary structure of human fibronectin: differential splicing may generate at least 10 polypeptides from a single gene.

1985 • 659 citations

Structure of the calcium regulatory muscle protein troponin-C at 2.8 Å resolution

1985 • 619 citations

A new protein of the thick filaments of vertebrate skeletal myofibrils

1973 • 615 citations

The organization of titin filaments in the half-sarcomere revealed by monoclonal antibodies in immunoelectron microscopy: a map of ten nonrepetitive epitopes starting at the Z line extends close to the M line.

1988 • 608 citations

Myosin Structure and Function in Cell Motility

1987 • 479 citations

The actin genes of drosophila: a dispersed multigene family

1980 • 470 citations

Actin Polymerization and ATP Hydrolysis

1987 • 439 citations

A vinculin-containing cortical lattice in skeletal muscle: transverse lattice elements ("costameres") mark sites of attachment between myofibrils and sarcolemma.

1983 • 432 citations

Microinjection and localization of a 130K protein in living fibroblasts: a relationship to actin and fibronectin

1980 • 406 citations

Sequence of an unusually large protein implicated in regulation of myosin activity in C. elegans

1989 • 368 citations

Tropomyosin crystal structure and muscle regulation

1986 • 324 citations

AN ANALYSIS OF MYOGENESIS BY THE USE OF FLUORESCENT ANTIMYOSIN

1957 • 324 citations

Differential localization of two myosins within nematode thick filaments

1983 • 303 citations

Video image processing greatly enhances contrast, quality, and speed in polarization-based microscopy.

1981 • 303 citations

Periodic features in the amino acid sequence of nematode myosin rod

1983 • 301 citations

Mutants with altered muscle structure in Caenorhabditis elegans

1980 • 272 citations

The relationship between stress fiber-like structures and nascent myofibrils in cultured cardiac myocytes.

1984 • 264 citations

The basal component of the nematode dense-body is vinculin

1989 • 254 citations

Cellular and molecular biology of muscle development

1990 • 248 citations

Structural relationships of actin, myosin, and tropomyosin revealed by cryo-electron microscopy.

1987 • 248 citations

Muscle organization in Caenorhabditis elegans: localization of proteins implicated in thin filament attachment and I-band organization.

1985 • 244 citations

A regular pattern of two types of 100-residue motif in the sequence of titin

1990 • 244 citations

Structure of co-crystals of tropomyosin and troponin

1987 • 242 citations

Does titin regulate the length of muscle thick filaments?

1989 • 240 citations

Assembly of Bacterial Ribosomes

1973 • 232 citations

A mutant affecting the heavy chain of myosin in Caenorhabditis elegans

1974 • 221 citations

A molecular basis for familial hypertrophic cardiomyopathy: An αβ cardiac myosin heavy chain hybrid gene

1990 • 221 citations

Differential distribution of subsets of myofibrillar proteins in cardiac nonstriated and striated myofibrils.

1990 • 213 citations

Regulatory and structural motifs of chicken gizzard myosin light chain kinase.

1990 • 208 citations

A role for integrin in the formation of sarcomeric cytoarchitecture

1990 • 207 citations

Polypeptide chains of intermediate molecular weight in myosin preparations

1971 • 206 citations

Endocrine regulation of protein breakdown in skeletal muscle

1988 • 199 citations

unc-93(e1500): A BEHAVIORAL MUTANT OF CAENORHABDITIS ELEGANS THAT DEFINES A GENE WITH A WILD-TYPE NULL PHENOTYPE

1980 • 190 citations

The ultrastructural location of C-protein, X-protein and H-protein in rabbit muscle

1986 • 188 citations

CAMs and Igs: Cell Adhesion and the Evolutionary Origins of Immunity

1987 • 187 citations

MOLECULAR GENETICS OF MYOSIN

1987 • 187 citations

Purification and initial characterization of a protein from skeletal muscle that caps the barbed ends of actin filaments.

1986 • 174 citations

Molecular and Cell Isoforms During Development

1983 • 172 citations

Studies on the Formation and Physical Chemical Properties of Synthetic Myosin Filaments^*

1966 • 162 citations

P22 morphogenesis I: Catalytic scaffolding protein in capsid assembly

1974 • 160 citations

Talin at myotendinous junctions.

1986 • 155 citations

Taxol induces postmitotic myoblasts to assemble interdigitating microtubule-myosin arrays that exclude actin filaments.

1981 • 154 citations

Isolation and characterization of a cDNA clone encoding avian skeletal muscle C-protein: an intracellular member of the immunoglobulin superfamily.

1990 • 152 citations

Cap Z(36/32), a barbed end actin-capping protein, is a component of the Z-line of skeletal muscle.

1987 • 152 citations

Titin is an extraordinarily long, flexible, and slender myofibrillar protein.

1984 • 141 citations

Video‐enhanced contrast polarization (AVEC‐POL) microscopy: A new method applied to the detection of birefringence in the motile reticulopodial network of allogromia laticollaris

1981 • 135 citations

Molecular genetics of Drosophila alpha-actinin: mutant alleles disrupt Z disc integrity and muscle insertions.

1990 • 135 citations

Paramyosin gene (unc-15) of Caenorhabditis elegans

1989 • 133 citations

Heterogeneity of contractile proteins. Differences in tropomyosin in fast, mixed, and slow skeletal muscles of the rabbit.

1982 • 129 citations

Structure of the backbone in myosin filaments of muscle

1979 • 128 citations

Differential expression and 5′ end mapping of actin genes in Dictyostelium

1981 • 127 citations

Distribution of fluorescently labeled actin in living sea urchin eggs during early development.

1979 • 121 citations

Self-association in the myosin system at high ionic strength. II. Evidence for the presence of a monomer ⇔ dimer equilibrium

1970 • 119 citations

Myosin and paramyosin are organized about a newly identified core structure.

1985 • 112 citations

Identification of genetic elements associated with muscle structure in the nematode caenorhabditis elegans

1980 • 111 citations

Mutations in the unc-54 myosin heavy chain gene of caenorhabditis elegans that alter contractility but not muscle structure

1982 • 110 citations

Sequence analysis of the complete Caenorhabditis elegans myosin heavy chain gene family

1989 • 109 citations

Molecular and ultrastructural defects in a Drosophila myosin heavy chain mutant: differential effects on muscle function produced by similar thick filament abnormalities.

1988 • 107 citations

Arrangement of myosin heads in relaxed thick filaments from frog skeletal muscle

1986 • 101 citations

Tropomyosin has discrete actin-binding sites with sevenfold and fourteenfold periodicities

1990 • 94 citations

Structural Implications of the Myosin Amino Acid Sequence

1984 • 91 citations

The unc-45 gene of Caenorhabditis elegans is an essential muscle-affecting gene with maternal expression.

1990 • 88 citations

Electron microscopy and image analysis of myosin filaments from scallop striated muscle

1983 • 87 citations

Localization of C-protein isoforms in chicken skeletal muscle: ultrastructural detection using monoclonal antibodies.

1984 • 85 citations

Heterogeneity of contractile proteins. A continuum of troponin-tropomyosin expression in mammalian skeletal muscle.

1985 • 85 citations

Dominant mutations affecting muscle structure in Caenorhabditis elegans that map near the actin gene cluster

1984 • 84 citations

Myosin minifilaments

1980 • 83 citations

The flightless drosophila mutant raised has two distinct genetic lesions affecting accumulation of myofibrillar proteins in flight muscles

1985 • 77 citations

Assembly Processes in Vertebrate Skeletal Thick Filament Formation

1988 • 74 citations

Clenbuterol, a beta 2-agonist, retards atrophy in denervated muscles

1987 • 74 citations

Packing analysis of crystalline myosin subfragment-1

1985 • 73 citations

Muscle development in Caenorhabditis elegans: Mutants exhibiting retarded sarcomere construction

1978 • 71 citations

An electron microscopic and optical diffraction analysis of the structure of Limulus telson muscle thick filaments.

1982 • 70 citations

The scope of moderate pressure changes for kinetic and equilibrium studies of biochemical systems

1976 • 69 citations

Skelemins: cytoskeletal proteins located at the periphery of M-discs in mammalian striated muscle.

1987 • 58 citations

Dynamic exchange of myosin molecules between thick filaments.

1986 • 53 citations

Assembly of the Native Heterodimer of Rana esculenta Tropomyosin by Chain Exchange

1989 • 53 citations

The alteration of myosin isoform compartmentation in specific mutants of Caenorhabditis elegans.

1986 • 51 citations

Visualization of cardiac ventricular myosin heavy chain homodimers and heterodimers by monoclonal antibody epitope mapping.

1987 • 46 citations

The assembly of tobacco mosaic virus: structure and specificity.

1980 • 39 citations

Novel thick filament protein of chicken pectoralis muscle: the 86 kd protein

1985 • 39 citations

Sequential disassembly of vertebrate muscle thick filaments

1980 • 37 citations

Cryo-electron microscopic studies of relaxed striated muscle thick filaments

1990 • 35 citations

Association of microinjected myosin and its subfragments with myofibrils in living muscle cells.

1988 • 32 citations

Growth of synthetic myosin filaments from myosin minifilaments

1982 • 31 citations

Renaturation of skeletal muscle tropomyosin: implications for in vivo assembly.

1985 • 30 citations

Size and charge heterogeneity of C-protein isoforms in avian skeletal muscle. Expression of six different isoforms in chicken muscle

1989 • 29 citations

Kinetics and thermodynamics of the assembly of the parallel- and antiparallel-packed sections of synthetic thick filaments of skeletal myosin: a pressure-jump study

1985 • 27 citations

Native bare zone assemblage nucleates myosin filament assembly

1982 • 27 citations

Bacteriophage T4 assembly and the morphogenesis of subcellular structure.

1979 • 22 citations

MOLECULAR GENETICS OF NEMATODE MUSCLE

1989 • 22 citations

MgATP specifically controls in vitro self-assembly of vertebrate skeletal myosin in the physiological pH range

1985 • 19 citations

Study of contractile and cytoskeletal proteins using Drosophila genetics

1989 • 17 citations

α‐Helix‐to‐random‐coil transitions of two‐chain coiled coils: Experiments on the thermal denaturation of ββ tropomyosin cross‐linked selectively at C‐190

1988 • 14 citations

Molecular genetic approaches to the study of motility in Caenorhabditis elegans

1989 • 13 citations

Genetic analysis of myosin assembly inCaenorhabditis elegans

1990 • 13 citations

Bacterial expression of eukaryotic contractile proteins

1989 • 13 citations

Structure‐function analysis of thin filament proteins expressed in Escherichia coli

1989 • 13 citations

The myosin filament. XII. Effect of MgATP on assembly

1986 • 12 citations

Modulation of myosin assembly

1988 • 10 citations

UNUSUAL STRIATED THICK FILAMENTS IN LIMULUS SKELETAL MUSCLE

1973 • 8 citations