Inhibition of tumor growth by elimination of granulocytes.

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity.

1993 • 2,828 citations

Characterization of the Murine Antigenic Determinant, Designated L3T4a, Recognized by Monoclonal Antibody GK 1.5: Expression of L3T4a by Functional T Cell Clones Appears to Correlate Primarily with Class II MHC Antigen‐Reactivity

1983 • 1,040 citations

Molecular cloning of gene sequences regulated by platelet-derived growth factor

1983 • 989 citations

Expression and secretion of type beta transforming growth factor by activated human macrophages.

1987 • 981 citations

Cytokines in context.

1991 • 808 citations

Murine interleukin-4 displays potent anti-tumor activity in vivo

1989 • 790 citations

A significant part of macrophage-derived growth factor consists of at least two forms of PDGF

1985 • 719 citations

An Eosinophil-Dependent Mechanism for the Antitumor Effect of Interleukin-4

1992 • 540 citations

Characterization and regulation of RB6-8C5 antigen expression on murine bone marrow cells.

1991 • 512 citations

Antigenicity of Murine Skin Tumors Induced by Ultraviolet Light2

1974 • 484 citations

Poly's lament: the neglected role of the polymorphonuclear neutrophil in the afferent limb of the immune response

1992 • 459 citations

Cloning and expression of JE, a gene inducible by platelet-derived growth factor and whose product has cytokine-like properties.

1988 • 444 citations

Leukocyte-endothelial cell recognition: evidence of a common molecular mechanism shared by neutrophils, lymphocytes, and other leukocytes.

1987 • 417 citations

Immunoreactive fibroblast growth factor in cells of peritoneal exudate suggests its identity with macrophage-derived growth factor

1985 • 372 citations

Neutrophils are essential for early anti-Listeria defense in the liver, but not in the spleen or peritoneal cavity, as revealed by a granulocyte-depleting monoclonal antibody.

1994 • 352 citations

Granulocyte colony-stimulating factor gene transfer suppresses tumorigenicity of a murine adenocarcinoma in vivo.

1991 • 315 citations

Production of transforming growth factor beta by human peripheral blood monocytes and neutrophils

1989 • 260 citations

Fibroblast cell interactions with human melanoma cells affect tumor cell growth as a function of tumor progression.

1991 • 217 citations

Local cytokine availability elicits tumor rejection and systemic immunity through granulocyte-T-lymphocyte cross-talk.

1992 • 187 citations

TGF-β Regulates Production of Growth Factors and TGF-β by Human Peripheral Blood Monocytes

1990 • 178 citations

Stroma is critical for preventing or permitting immunological destruction of antigenic cancer cells.

1992 • 169 citations

CAP37, a human neutrophil-derived chemotactic factor with monocyte specific activity.

1990 • 151 citations

Secretion by human fibroblasts of monocyte chemoattractant protein-1, the product of gene JE.

1990 • 145 citations

Production of platelet-activating factor by stimulated human polymorphonuclear leukocytes. Correlation of synthesis with release, functional events, and leukotriene B4 metabolism.

1987 • 145 citations

Stimulation of human prostatic carcinoma cell growth by factors present in human bone marrow.

1989 • 136 citations

Loss of growth factor dependence and conversion of transforming growth factor-beta 1 inhibition to stimulation in metastatic H-ras-transformed murine fibroblasts.

1988 • 113 citations

Major histocompatibility complex class I and unique antigen expression by murine tumors that escaped from CD8+ T-cell-dependent surveillance.

1990 • 91 citations

Granulocyte colony-stimulating factor (G-CSF) gene transduction in murine adenocarcinoma drives neutrophil-mediated tumor inhibition in vivo. Neutrophils discriminate between G-CSF-producing and G-CSF-nonproducing tumor cells.

1992 • 88 citations

Platelet-derived growth factors

1989 • 85 citations

Selective stimulation of prostatic carcinoma cell proliferation by transferrin.

1992 • 76 citations

Resistance of human tumor cells in vitro to oxidative cytolysis.

1985 • 63 citations

Linkage of superantigen-like stimulation of syngeneic T cells in a mouse model of follicular center B cell lymphoma to transcription of endogenous mammary tumor virus.

1993 • 61 citations

Modulation of in vivo immune response by selective depletion of neutrophils using a monoclonal antibody, RP-3. II. Inhibition by RP-3 treatment of mononuclear leukocyte recruitment in delayed-type hypersensitivity to sheep red blood cells in rats.

1993 • 49 citations

Characterization and growth factor requirements of SJL lymphomas. I. Development of a B cell growth factor-dependent in vitro cell line, cRCS-X.

1988 • 40 citations

Footprinting of individual tumors and their variants by constitutive cytokine expression patterns.

1993 • 23 citations