Lack of Association between Enhanced TRPM-2/Clusterin Expression and Increased Apoptotic Activity in Sex-Hormone-Induced Prostatic Dysplasia of the Noble Rat

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Intraductal dysplasia: A premalignant lesion of the prostate

1986 • 584 citations

One-hour downward alkaline capillary transfer for blotting of DNA and RNA

1992 • 551 citations

Induction of the TRPM-2 gene in cells undergoing programmed death.

1989 • 466 citations

BCL-2 family proteins: Regulators of cell death involved in the pathogenesis of cancer and resistance to therapy

1996 • 420 citations

Expression of Transforming Growth Factor-β in the Rat Ventral Prostate during Castration-Induced Programmed Cell Death

1989 • 417 citations

Molecular structure and functional characterization of a human complement cytolysis inhibitor found in blood and seminal plasma: identity to sulfated glycoprotein 2, a constituent of rat testis fluid.

1989 • 412 citations

Purification and characterization of a cell-aggregating factor (clusterin), the major glycoprotein in ram rete testis fluid.

1983 • 399 citations

Apolipoprotein J: structure and tissue distribution

1990 • 339 citations

Biosynthesis and molecular cloning of sulfated glycoprotein 2 secreted by rat Sertoli cells

1987 • 336 citations

Dynamics of gene expression for a hippocampal glycoprotein elevated in Alzheimer's disease and in response to experimental lesions in rat

1990 • 334 citations

Active cell death in hormone-dependent tissues

1992 • 264 citations

Androgen‐repressed messages in the rat ventral prostate

1986 • 261 citations

Characterization and cloning of androgen-repressed mRNAs from rat ventral prostate

1987 • 256 citations

Prevention of cell death induced by tumor necrosis factor alpha in LNCaP cells by overexpression of sulfated glycoprotein-2 (clusterin).

1995 • 224 citations

In situ hybridization methods for the detection of somatostatin mRNA in tissue sections using antisense RNA probes

1986 • 207 citations

Molecular biology of prostatic intraepithelial neoplasia

1996 • 207 citations

Biochemical Alterations in Sex Hormone-Induced Hyperplasia and Dysplasia of the Dorsolateral Prostates of Noble Rats

1988 • 187 citations

Nucleotide sequence of cloned cDNAs encoding human preproparathyroid hormone.

1981 • 183 citations

Induction at high incidence of ductal prostate adenocarcinomas in NBL/Cr and Sprague-Dawley Hsd:SD rats treated with a combination of testosterone and estradiol-17β or diethylstilbestrol

1995 • 174 citations

Sulfated glycoprotein 2: new relationships of this multifunctional protein to neurodegeneration

1992 • 171 citations

Mitogen-activated protein kinase phosphatase 1 is overexpressed in prostate cancers and is inversely related to apoptosis.

1997 • 157 citations

Androgen‐supported estrogen‐enhanced epithelial proliferation in the prostates of intact noble rats

1989 • 146 citations

Comparison of 35S- and digoxigenin-labeled RNA and oligonucleotide probes for in situ hybridization

1992 • 129 citations

Bcl-XL protects cancer cells from p53-mediated apoptosis.

1995 • 126 citations

The lurcher gene induces apoptotic death in cerebellar Purkinje cells

1995 • 119 citations

Purification and characterization of a sulfated glycoprotein secreted by Sertoli cells

1986 • 119 citations

Apoptosis — Molecular mechanisms and biomedical implications

1996 • 113 citations

Apoptosis in decidual tissue regression and reorganization.

1994 • 107 citations

Incidence of apoptosis and cell proliferation in prostate cancer: Relationship with TGF-β1 and bcl-2 expression

1996 • 104 citations

Prostatic Ductal System in Rats: Regional Variation in Localization of an Androgen-Repressed Gene Product, Sulfated Glycoprotein-2*

1991 • 100 citations

The primary structure of glycoprotein III from bovine adrenal medullary chromaffin granules. Sequence similarity with human serum protein-40,40 and rat Sertoli cell glycoprotein.

1990 • 96 citations

Lobe-specific apoptotic cell death in rat prostate after androgen ablation by castration.

1995 • 89 citations

Androgen dependence of specific kallikrein gene family members expressed in rat prostate.

1988 • 84 citations

Apoptosis: Its Role in the Development of Malignancies and its Potential as a Novel Therapeutic Target

1997 • 80 citations

Diverse Secretory Patterns of Clusterin by Epididymis and Prostate/Seminal Vesicles Undergoing Cell Regression after Orchiectomy*

1990 • 67 citations

SGP-2 expression as a genetic marker of progressive cellular pathology in experimental hydronephrosis

1991 • 67 citations

The induction of NB rat prostatic carcinomas.

1984 • 57 citations

Castration induces apoptosis in the ventral prostate but not in an androgen-sensitive prostatic adenocarcinoma in the rat.

1994 • 54 citations

Induction of the TRPM-2 Gene in Cells Undergoing Programmed Death

1989 • 53 citations

Expression of clusterin in cell differentiation and cell death

1994 • 51 citations

Loss of androgen dependence is associated with an increase in tumorigenic stem cells and resistance to cell-death genes

1990 • 44 citations

Effects of intermittent androgen suppression on the stem cell composition and the expression of the TRPM-2 (clusterin) gene in the Shionogi carcinoma

1996 • 43 citations

Radioresistance, Chemoresistance, and Apoptosis Resistance

1997 • 43 citations

Mitogen-activated protein kinase and mitogen-activated kinase phosphatase-1 expression in the Noble rat model of sex hormone-induced prostatic dysplasia and carcinoma.

1996 • 36 citations

Sequential Androgen Blockade: A Biological Study in the Inhibition of Prostatic Growth

1992 • 30 citations

Increased levels of clusterin mRNA in the ventral prostate of the aging rat are associated to increases in cuboidal (atrophic) cell population and not to changes in apoptotic activity

1994 • 25 citations

TRPM‐2 gene expression in normal rat ventral prostate following castration and exposure to diethylstilbestrol, flutamide, MK‐906 (finasteride), and coumarin

1994 • 21 citations

Effect of tumour progression on the androgenic regulation of the androgen receptor, TRPM-2 and YPT1 genes in the Shionogi carcinoma

1994 • 20 citations

Follicular atresia as an apoptotic process: Atresia-associated increase in the ovarian expression of the putative apoptotic marker sulfated glycoprotein-2

1996 • 8 citations

Follicular Atresia as an Apoptotic Process: Atresia-Associated Increase in the Ovarian Expression of the Putative Apoptotic Marker Sulfated Glycoprotein-2

1996 • 7 citations