Effects of intermittent androgen suppression on the stem cell composition and the expression of the TRPM-2 (clusterin) gene in the Shionogi carcinoma

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

Number and evolutionary conservation of α- and β-tubulin and cytoplasmic β- and γ-actin genes using specific cloned cDNA probes

1980 • 1,884 citations

Programmed cell death during regression of PC-82 human prostate cancer following androgen ablation.

1990 • 485 citations

Induction of the TRPM-2 gene in cells undergoing programmed death.

1989 • 466 citations

Molecular structure and functional characterization of a human complement cytolysis inhibitor found in blood and seminal plasma: identity to sulfated glycoprotein 2, a constituent of rat testis fluid.

1989 • 412 citations

Effects of intermittent androgen suppression on androgen-dependent tumors. Apoptosis and serum prostate-specific antigen

1993 • 380 citations

Clusterin: the intriguing guises of a widely expressed glycoprotein

1992 • 353 citations

Apolipoprotein J: structure and tissue distribution

1990 • 339 citations

Biosynthesis and molecular cloning of sulfated glycoprotein 2 secreted by rat Sertoli cells

1987 • 336 citations

Effects of androgen withdrawal on the stem cell composition of the Shionogi carcinoma.

1990 • 314 citations

SP-40,40, a newly identified normal human serum protein found in the SC5b-9 complex of complement and in the immune deposits in glomerulonephritis.

1988 • 311 citations

Nuclear import of the human androgen receptor

1993 • 277 citations

Hormonal Effects on Cell Proliferation in Rat Prostate

1976 • 264 citations

Active cell death in hormone-dependent tissues

1992 • 264 citations

Androgen‐repressed messages in the rat ventral prostate

1986 • 261 citations

Characterization and cloning of androgen-repressed mRNAs from rat ventral prostate

1987 • 256 citations

Hormone-regulated apoptosis results from reentry of differentiated prostate cells onto a defective cell cycle.

1992 • 245 citations

Molecular cloning and characterization of the novel, human complement-associated protein, SP-40,40: a link between the complement and reproductive systems.

1989 • 243 citations

A Sulfated Glycoprotein Synthesized by Sertoli Cells and by Epididymal Cells is a Component of the Sperm Membrane 1

1984 • 226 citations

Prevention of cell death induced by tumor necrosis factor alpha in LNCaP cells by overexpression of sulfated glycoprotein-2 (clusterin).

1995 • 224 citations

Genomic organization and expression of the rat TRPM-2 (clusterin) gene, a gene implicated in apoptosis.

1993 • 194 citations

Identification of an androgen-repressed mRNA in rat ventral prostate as coding for sulphated glycoprotein 2 by cDNA cloning and sequence analysis

1989 • 183 citations

Human clusterin gene expression is confined to surviving cells during in vitro programmed cell death.

1994 • 170 citations

Multitype Branching Processes.

1973 • 157 citations

Nuclear location signal-mediated protein transport

1989 • 144 citations

An androgen-dependent mouse mammary tumor.

1965 • 139 citations

Analysis of Sertoli Cell-Secreted Proteins by Two-Dimensional Gel Electrophoresis

1982 • 136 citations

Multi-Type Branching Processes

1972 • 132 citations

Purification and characterization of a sulfated glycoprotein secreted by Sertoli cells

1986 • 119 citations

SP-40,40 is an inhibitor of C5b-6-initiated haemolysis

1989 • 115 citations

Hormonal control of growth and progression in tumors of Nb rats and a theory of action.

1977 • 112 citations

Progression to steroid insensitivity can occur irrespective of the presence of functional steroid receptors

1987 • 105 citations

Gene expression during the early phases of regression of the androgen-dependent Shionogi mouse mammary carcinoma.

1988 • 88 citations

Structural analysis of clusterin and its subunits in ram rete testis fluid

1988 • 84 citations

Cloning of the human glucocorticoid receptor cDNA

1985 • 79 citations

The gene for SP-40,40, human homolog of rat sulfated glycoprotein 2, rat clusterin, and rat testosterone-repressed prostate message 2, maps to chromosome 8

1991 • 71 citations

Characterization of a human high density lipoprotein-associated protein, NA1/NA2. Identity with SP-40,40, an inhibitor of complement-mediated cytolysis.

1991 • 70 citations

Diverse Secretory Patterns of Clusterin by Epididymis and Prostate/Seminal Vesicles Undergoing Cell Regression after Orchiectomy*

1990 • 67 citations

Incorporation of SP-40,40 into the solyble membrance attack complex(SMAC, SC5b-9) of complement

1990 • 65 citations

Expression of a novel gene encoding a 51.5 kD precursor protein is induced by different retroviral oncogenes in quail neuroretinal cells.

1989 • 53 citations

Cortisol Alters Gene Expression during Involution of the Rat Ventral Prostate

1989 • 51 citations

Clusterin enhances the formation of insoluble immune complexes

1991 • 49 citations

Sulfated glycoprotein-2 expression increases in rodent brain after transient global ischemia

1992 • 45 citations

Clusterin (SGP‐2) in epididymal luminal fluid and its association with epididymal spermatozoa in androgen‐deprived rats

1992 • 22 citations

Antibodies to rat sertoli cell secretory proteins recognize antigenic sites in acrosome and tail of developing spermatids and sperm

1988 • 22 citations

Effect of tumour progression on the androgenic regulation of the androgen receptor, TRPM-2 and YPT1 genes in the Shionogi carcinoma

1994 • 20 citations

Characterisation of the nuclear location sequence of Xenopus nucleoplasmin

1989 • 17 citations

Loss of androgen dependency with preservation of functional androgen receptors in androgen-dependent mouse tumor (Shionogi carcinoma 115)

1992 • 14 citations

Variability of androgen-related phenotypes in the Shionogi mammary carcinoma during growth, involution, recurrence, and progression to hormonal independence.

1985 • 13 citations

Control of proliferative growth in androgen responsive organs and neoplasms.

1976 • 12 citations

Antibodies to rat sperm tail polypeptides recognize Sertoli cell secretory proteins

1989 • 8 citations