Experimental determination of flux control distribution in biochemical systems: In vitro model to analyze transient metabolite concentrations

Methods of Enzymatic Analysis

1974 • 6,512 citations

A Linear Steady-State Treatment of Enzymatic Chains. General Properties, Control and Effector Strength

1974 • 1,378 citations

Metabolic control analysis: a survey of its theoretical and experimental development

1992 • 786 citations

Metabolic control theory: A structural approach

1988 • 560 citations

Control of Metabolic Processes

1990 • 290 citations

Lumping Analysis in Monomolecular Reaction Systems. Analysis of Approximately Lumpable System

1969 • 269 citations

Fermentation pathway kinetics and metabolic flux control in suspended and immobilized Saccharomyces cerevisiae

1990 • 243 citations

Lumping Analysis in Monomolecular Reaction Systems. Analysis of the Exactly Lumpable System

1969 • 240 citations

Parameter Sensitivity as a Criterion for Evaluating and Comparing the Performance of Biochemical Systems

1971 • 224 citations

Control analysis of metabolic systems

1985 • 187 citations

Control of gluconeogenesis in rat liver cells. Flux control coefficients of the enzymes in the gluconeogenic pathway in the absence and presence of glucagon

1986 • 175 citations

Matrix method for determining steps most rate‐limiting to metabolic fluxes in biotechnological processes

1987 • 125 citations

Metabolic control and its analysis

1987 • 120 citations

Matrix method for determining steps most rate‐limiting to metabolic fluxes in biotechnological processes

2009 • 93 citations

Enzyme‐enzyme interactions and control analysis

1990 • 89 citations

Enzyme‐enzyme interactions and control analysis

1990 • 79 citations

Advances in Metabolic Control Analysis

1993 • 73 citations

The definitions of metabolic control analysis revisited

1992 • 66 citations

Determination of Flux Control Coefficients from transient metabolite concentrations

1992 • 62 citations

Metabolic control analysis using transient metabolite concentrations. Determination of metabolite concentration control coefficients

1992 • 38 citations

Study of the flux and transition time control coefficient profiles in a metabolic system in vitro and the effect of an external stimulator

1989 • 37 citations

Lumping analysis of biochemical reaction systems with time scale separation

1988 • 34 citations

Characteristic reaction paths of biochemical reaction systems with time scale separation

1988 • 20 citations

A generalization of Metabolic Control analysis to conditions of no proportionality between activity and concentration of enzymes

1990 • 11 citations

Dynamic Metabolic Control Theory

1992 • 9 citations