Control of gluconeogenesis in rat liver cells. Flux control coefficients of the enzymes in the gluconeogenic pathway in the absence and presence of glucagon

A Flexible System of Enzymatic Analysis

1972 • 4,133 citations

10 Methoden der enzymatischen Analyse

2019 • 3,602 citations

The control of flux.

1973 • 1,381 citations

A Linear Steady-State Treatment of Enzymatic Chains. General Properties, Control and Effector Strength

1974 • 1,378 citations

The Relationships between Substrates and Enzymes of Glycolysis in Brain

1964 • 551 citations

GLUCONEOGENESIS AND RELATED ASPECTS OF GLYCOLYSIS

1983 • 523 citations

Molecular Democracy: Who Shares the Controls?

1979 • 454 citations

Glycolytic Control Mechanisms

1965 • 373 citations

Metabolic control and its analysis. Additional relationships between elasticities and control coefficients

1985 • 316 citations

Control Mechanisms of Gluconeogenesis and Ketogenesis

1969 • 303 citations

Metabolic Compartmentation

1983 • 303 citations

Hormonal regulation of hepatic gluconeogenesis.

1984 • 272 citations

Determination of the mitochondrial protonmotive force in isolated hepatocytes.

1980 • 263 citations

Hormonal control of pyruvate kinase activity and of gluconeogenesis in isolated hepatocytes.

1976 • 215 citations

Intracellular Compartment ation and Control of Alanine Metabolism in Rat Liver Parenchymal Cells

1982 • 170 citations

The control of enzyme systems in vivo: Elasticity analysis of the steady state

1983 • 170 citations

Pyruvate and ketone-body transport across the mitochondrial membrane. Exchange properties, pH-dependence and mechanism of the carrier

1978 • 169 citations

Determination of mitochondrial/cytosolic metabolite gradients in isolated rat liver cells by cell disruption

1977 • 164 citations

Control of Hepatic Mitochondrial CO2 Fixation by Glucagon, Epinephrine, and Cortisol

1969 • 163 citations

Mechanism of 3-mercaptopicolinic acid inhibition of hepatic phosphoenolpyruvate carboxykinase (GTP).

1976 • 135 citations

Control of glycolysis in cerebral cortex slices

1967 • 131 citations

The Role of Futile Cycles in the Regulation of Carbohydrate Metabolism in the Liver

1981 • 124 citations

Distribution of Metabolites Between the Cytosolic and Mitochondrial Compartments of Hepatocytes Isolated from Fed Rats

1978 • 120 citations

Control of gluconeogenesis in rat liver cells. I. Kinetics of the individual enzymes and the effect of glucagon.

1983 • 110 citations

Plasma‐membrane transport of alanine is rate‐limiting for its metabolism in rat‐liver parenchymal cells

1980 • 88 citations

Cyclic AMP induced inhibition of pyruvate kinase flux in the intact liver cell

1975 • 86 citations

Pyruvate Carboxylase from Chicken Liver

1972 • 84 citations

Relationship between Oxygen Uptake of Perifused Rat-Liver Cells and the Cytosolic Phosphorylation State Calculated from Indicator Metabolites and a Redetermined Equilibrium Constant

1978 • 81 citations

The Equilibria of Reactions Catalyzed by Carboxytransphosphorylase, Carboxykinase, and Pyruvate Carboxylase and the Synthesis of Phosphoenolpyruvate

1966 • 79 citations

Control of pyruvate kinase activity by glucagon in isolated hepatocytes

1976 • 75 citations

The interaction between the cytosolic pyridine nucleotide redox potential and gluconeogenesis from lactate/pyruvate in isolated rat hepatocytes. Implications for investigations of hormone action.

1985 • 71 citations

Is the adenine nucleotide translocator rate-limiting for oxidative phosphorylation?

1978 • 61 citations

Subcellular Distribution of Di- and Tricarboxylates and pH Gradients in Perfused Rat Liver

1980 • 61 citations

Equilibrium constants of phosphoryl transfer from C(1) to C(6) of α-<scp>d</scp>-glucose 1-phosphate and from glucose 6-phosphate to water

1961 • 49 citations

Cyclic nucleotide-, pyruvate- and hormone-induced changes in pyruvate kinase activity in isolated rat hepatocytes

1976 • 47 citations

A re-evaluation of the role of mitochondrial pyruvate transport in the hormonal control of rat liver mitochondrial pyruvate metabolism

1984 • 47 citations

Effect of dichloroacetate and glucagon on the incorporation of labeled substrates into glucose and on pyruvate dehydrogenase in hepatocytes from fed and starved rats

1977 • 44 citations

Inhibition of gluconeogenesis and lactate formation from pyruvate by N6, O2'-dibutyryl adenosine 3':5'-monophosphate.

1976 • 35 citations

Hormonal stimulation of mitochondrial pyruvate carboxylation in filipin-treated hepatocytes

1983 • 30 citations

Kinetic studies of bovine liver fructose-1,6-bisphosphatase.

1979 • 25 citations

An evaluation of the metabolite indicator method for determining the cytosolic phosphate potential in rat liver cells

1982 • 15 citations

Enzymatic measurement of adenine and guanine(plus inosine) triphosphates and diphosphates in isolated cells and the mitochondrial matrix compartment obtained from rat liver

1979 • 9 citations

Sensitivity of pathway rate to activities of substrate-cycle enzymes: Application to gluconeogenesis and glycolysis

1984 • 6 citations