CD8+ Foxp3+ Regulatory T Cells Mediate Immunosuppression in Prostate Cancer

Inflammation and cancer

2002 • 14,174 citations

Control of Regulatory T Cell Development by the Transcription Factor Foxp3

2003 • 7,902 citations

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

2003 • 7,470 citations

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

2004 • 4,872 citations

N<scp>aturally</scp>A<scp>rising</scp>CD4⁺R<scp>egulatory</scp>T C<scp>ells for</scp>I<scp>mmunologic</scp>S<scp>elf</scp>-T<scp>olerance and</scp>N<scp>egative</scp>C<scp>ontrol of</scp>I<scp>mmune</scp>R<scp>esponses</scp>

2003 • 3,323 citations

Intratumoral T Cells, Recurrence, and Survival in Epithelial Ovarian Cancer

2003 • 3,194 citations

Cancer immunotherapy: moving beyond current vaccines

2004 • 2,932 citations

NF-κB: linking inflammation and immunity to cancer development and progression

2005 • 2,878 citations

Cancer Regression and Autoimmunity in Patients After Clonal Repopulation with Antitumor Lymphocytes

2002 • 2,781 citations

IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer

2004 • 2,361 citations

Regulatory T Cell Lineage Specification by the Forkhead Transcription Factor Foxp3

2005 • 2,256 citations

Intraepithelial CD8⁺tumor-infiltrating lymphocytes and a high CD8⁺/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer

2005 • 2,226 citations

Gr-1+CD115+ Immature Myeloid Suppressor Cells Mediate the Development of Tumor-Induced T Regulatory Cells and T-Cell Anergy in Tumor-Bearing Host

2006 • 1,366 citations

Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer.

2001 • 1,126 citations

Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody.

1999 • 1,066 citations

Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells

2005 • 998 citations

FOXP3: Of Mice and Men

2005 • 929 citations

Toll-like receptor 2 controls expansion and function of regulatory T cells

2006 • 756 citations

Toll-Like Receptor 8-Mediated Reversal of CD4 ⁺ Regulatory T Cell Function

2005 • 734 citations

Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single-cell level

2005 • 589 citations

Tumor-Specific Human CD4+ Regulatory T Cells and Their Ligands

2004 • 525 citations

Toll-like receptor 2 signaling modulates the functions of CD4⁺CD25⁺regulatory T cells

2006 • 441 citations

CD4+CD25high T Cells Are Enriched in the Tumor and Peripheral Blood of Prostate Cancer Patients

2006 • 416 citations

Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humans

2004 • 415 citations

Human CD8+CD25+ thymocytes share phenotypic and functional features with CD4+CD25+ regulatory thymocytes

2003 • 388 citations

Prostate carcinogenesis and inflammation: emerging insights

2004 • 385 citations

Plasmacytoid Dendritic Cells Induce CD8+ Regulatory T Cells In Human Ovarian Carcinoma

2005 • 376 citations

Essential Roles of CD8+CD122+ Regulatory T Cells in the Maintenance of T Cell Homeostasis

2004 • 305 citations

Inability of a Fusion Protein of IL-2 and Diphtheria Toxin (Denileukin Diftitox, DAB389IL-2, ONTAK) to Eliminate Regulatory T Lymphocytes in Patients With Melanoma

2005 • 293 citations

A randomized phase II study of concurrent docetaxel plus vaccine versus vaccine alone in metastatic androgen-independent prostate cancer.

2006 • 291 citations

An integrated view of suppressor T cell subsets in immunoregulation

2004 • 248 citations

The Specific Regulation Of Immune Responses By CD8⁺T Cells Restricted By The MHC Class Ib Molecule, Qa-1

2000 • 168 citations

Recognition of a New ARTC1 Peptide Ligand Uniquely Expressed in Tumor Cells by Antigen-Specific CD4+ Regulatory T Cells

2005 • 156 citations

License to Heal: Bidirectional Interaction of Antigen-Specific Regulatory T Cells and Tolerogenic APC

2005 • 147 citations

Qa-1 restriction of CD8+ suppressor T cells

2004 • 142 citations

Peripheral CD8+CD25+ T Lymphocytes from MHC Class II-Deficient Mice Exhibit Regulatory Activity

2005 • 98 citations

Autoreactive human peripheral blood CD8⁺ T cells with a regulatory phenotype and function

2005 • 93 citations

Inflammation and prostate cancer.

2006 • 62 citations

Regulatory T cells and Toll-like receptors in tumor immunity

2006 • 53 citations

Immune regulation in tumor-bearing hosts

2006 • 51 citations

Enhancing antitumor immune responses: intracellular peptide delivery and identification of MHC class II‐restricted tumor antigens

2002 • 49 citations

Functional control of regulatory T cells and cancer immunotherapy

2006 • 44 citations

Altered Immunity Accompanies Disease Progression in a Mouse Model of Prostate Dysplasia

2005 • 39 citations

Immune-based therapies for prostate cancer

2004 • 30 citations

Immunotherapy for prostate cancer

2007 • 20 citations

Emerging role of immunotherapy in the management of prostate cancer.

2007 • 16 citations