Randomised, double blind, placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease: the ISOLDE trial

Alternative projections of mortality and disability by cause 1990–2020: Global Burden of Disease Study

1997 • 7,096 citations

Multilevel Statistical Models

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Mortality by cause for eight regions of the world: Global Burden of Disease Study

1997 • 4,053 citations

A Self-complete Measure of Health Status for Chronic Airflow Limitation: The St. George's Respiratory Questionnaire

1992 • 2,933 citations

Multilevel Statistical Models

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The St George's Respiratory Questionnaire

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The natural history of chronic airflow obstruction.

1977 • 2,340 citations

Effect of Exacerbation on Quality of Life in Patients with Chronic Obstructive Pulmonary Disease

1998 • 2,273 citations

Standardization of Spirometry—1987 Update

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Effects of smoking intervention and the use of an inhaled anticholinergic bronchodilator on the rate of decline of FEV1. The Lung Health Study

1994 • 1,581 citations

Long-Term Treatment with Inhaled Budesonide in Persons with Mild Chronic Obstructive Pulmonary Disease Who Continue Smoking

1999 • 1,057 citations

Long-term effect of inhaled budesonide in mild and moderate chronic obstructive pulmonary disease: a randomised controlled trial

1999 • 833 citations

The natural history of chronic bronchitis and emphysema

1979 • 619 citations

Sputum eosinophilia and short-term response to prednisolone in chronic obstructive pulmonary disease: a randomised controlled trial

2000 • 570 citations

Multicentre randomised placebo-controlled trial of inhaled fluticasone propionate in patients with chronic obstructive pulmonary disease

1998 • 517 citations

Nasal pressure support ventilation plus oxygen compared with oxygen therapy alone in hypercapnic COPD.

1995 • 463 citations

Airways obstruction, chronic expectoration, and rapid decline of FEV1 in smokers are associated with increased levels of sputum neutrophils.

1996 • 440 citations

Sputum Eosinophilia Predicts Benefit from Prednisone in Smokers with Chronic Obstructive Bronchitis

1998 • 394 citations

Quality of life and hospital re-admission in patients with chronic obstructive pulmonary disease

1997 • 359 citations

Structural and inflammatory changes in COPD: a comparison with asthma.

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Methacholine reactivity predicts changes in lung function over time in smokers with early chronic obstructive pulmonary disease. The Lung Health Study Research Group.

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Spirometry in the Lung Health Study: 1. Methods and Quality Control

1991 • 291 citations

Another smoking hazard: raised serum IgE concentration and increased risk of occupational allergy.

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Partial Reversibility of Airflow Limitation and Increased Exhaled NO and Sputum Eosinophilia in Chronic Obstructive Pulmonary Disease

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Susceptibility Genes for Rapid Decline of Lung Function in the Lung Health Study

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Oral mucolytic drugs for exacerbations of chronic obstructive pulmonary disease: systematic review

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The host factor in bronchitis

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Oral Corticosteroid Therapy for Patients with Stable Chronic Obstructive Pulmonary Disease

1991 • 232 citations

The Role of Allergy and Nonspecific Airway Hyperresponsiveness in the Pathogenesis of Chronic Obstructive Pulmonary Disease

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Slowing the Deterioration of Asthma and Chronic Obstructive Pulmonary Disease Observed during Bronchodilator Therapy by Adding Inhaled Corticosteroids: A 4-Year Prospective Study

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Long term effects of inhaled corticosteroids in chronic obstructive pulmonary disease: a meta-analysis

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Airway hyperresponsiveness to histamine associated with accelerated decline in FEV1.

1995 • 167 citations

An observational study of inhaled corticosteroid withdrawal in stable chronic obstructive pulmonary disease

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Independent influence of reversibility of air-flow obstruction and nonspecific hyperreactivity on the long-term course of lung function in chronic air-flow obstruction.

1986 • 152 citations

A prospective longitudinal study of methacholine airway responsiveness as a predictor of pulmonary-function decline: the Normative Aging Study.

1995 • 141 citations

Moderately severe chronic airflow obstruction. Can corticosteroids slow down obstruction?

1988 • 113 citations

Pharmacokinetics of Triamcinolone Acetonide After Intravenous, Oral, and Inhaled Administration

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International Comparisons in COPD Mortality

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Smoking, allergy, and the differential white blood cell count.

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Allergy markers in respiratory epidemiology

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Fluticasone propionate powder and lack of clinically significant effects on hypothalamic-pituitary-adrenal axis and bone mineral density over 2 years in adults with mild asthma

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Skin test reactivity to common aeroallergens and decline of lung function. The Normative Aging Study.

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Issues at the interface between primary and secondary care in the management of common respiratory disease bullet 5: The challenge of providing better care for patients with chronic obstructive pulmonary disease: the poor relation of airways obstruction?

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Eosinophils, smoking, and lung function. An epidemiologic survey among 912 working men.

1986 • 39 citations

Changes in bronchial responsiveness to inhaled histamine over four years in middle aged male smokers and ex-smokers.

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Clinical evidence: Stable chronic obstructive pulmonary disease

1999 • 28 citations

Deleted Work

1955 • 0 citations