Synthesis of difluoromethyl substituted lysophosphatidic acid analogues

Atherosclerosis

2000 • 4,558 citations

The mouse peroxisome proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl CoA oxidase gene.

1992 • 903 citations

New fluorinating reagents. Dialkylaminosulfur fluorides

1975 • 848 citations

How good is fluorine as a hydrogen bond acceptor?

1996 • 694 citations

The macrophage foam cell as a target for therapeutic intervention

2002 • 684 citations

Lysophosphatidic Acid, a Multifunctional Phospholipid Messenger

1995 • 592 citations

Identification of p2y9/GPR23 as a Novel G Protein-coupled Receptor for Lysophosphatidic Acid, Structurally Distant from the Edg Family

2003 • 553 citations

Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARγ agonist

2002 • 545 citations

Hydrogen Bond Donor Properties of the Difluoromethyl Group

1995 • 544 citations

Lysophospholipids--Receptor Revelations

2001 • 539 citations

The facile dealkylation of phosphonic acid dialkyl esters by bromotrimethylsilane

1977 • 434 citations

Organic fluorine chemistry

1968 • 412 citations

Characterization of an ovarian cancer activating factor in ascites from ovarian cancer patients.

1995 • 325 citations

Lysophosphatidic acid is a bioactive mediator in ovarian cancer

2002 • 271 citations

Oxidized Alkyl Phospholipids Are Specific, High Affinity Peroxisome Proliferator-activated Receptor γ Ligands and Agonists

2001 • 262 citations

Lysophosphatidic acid (LPA) receptors of the EDG family are differentially activated by LPA species

2000 • 255 citations

Lysophospholipid Growth Factors in the Initiation, Progression, Metastases, and Management of Ovarian Cancer

2000 • 243 citations

Stereoselective Synthesis ofanti-α-(Difluoromethyl)-β-amino Alcohols by Boronic Acid Based Three-Component Condensation. Stereoselective Preparation of (2S,3R)-Difluorothreonine

2002 • 123 citations

Identification of a Phosphothionate Analogue of Lysophosphatidic Acid (LPA) as a Selective Agonist of the LPA3 Receptor

2003 • 121 citations

Synthetic methods and reactions. I. Seleniuum tetrafluoride and its pyridine complex. Convenient fluorinating agents for fluorination of ketones, aldehydes, amides, alcohols, carboxylic acids, and anhydrides

1974 • 113 citations

A remarkably simple route to versatile difluoromethylated molecules

1993 • 111 citations

Total Synthesis of (−)-Macrolactin A

1996 • 109 citations

Antiviral nucleosides. A stereospecific, total synthesis of 2'-fluoro-2'-deoxy-.beta.-D-arabinofuranosyl nucleosides

1988 • 87 citations

Increased Expression of Peroxisome Proliferator-Activated Receptor-α and -γ in Blood Vessels of Spontaneously Hypertensive Rats

2001 • 74 citations

Concise Synthesis of Acyl Migration-Blocked 1,1-Difluorinated Analogues of Lysophosphatidic Acid

2002 • 69 citations

Synthetic studies on the streptogramin antibiotics. Enantioselective synthesis of the oxazole dienyl amine moiety

1986 • 69 citations

Fluorination of Thiocarbonyl Compounds with Bis(2-methoxyethyl)aminosulfur Trifluoride (Deoxo-Fluor Reagent): A Facile Synthesis of gem-Difluorides

2000 • 61 citations

Synthesis of the (9S,18R) Diastereomer of Cyclamenol A

2000 • 48 citations

Efficient and selective dealkylation of phosphonate dilsopropyl esters using Me3SiBr

1995 • 40 citations

Stereochemical properties of lysophosphatidic acid receptor activation and metabolism

2002 • 35 citations

Application to the Synthesis of Enantiopure Phosphonates Analogous to Triglycerides: A New Class of Inhibitors of Lipases

1999 • 15 citations

Autocleavage ofO-Isopropylidene ProtectedO-Phosphono- andO- Thionophosphono Esters of Sugars

2000 • 5 citations

Deleted Work

1955 • 0 citations