Preferential Inhibition of BMAL2-CLOCK Activity by PER2 Reemphasizes Its Negative Role and a Positive Role of BMAL2 in the Circadian Transcription

Coordination of circadian timing in mammals

2002 • 4,132 citations

Molecular Bases for Circadian Clocks

1999 • 2,823 citations

The Orphan Nuclear Receptor REV-ERBα Controls Circadian Transcription within the Positive Limb of the Mammalian Circadian Oscillator

2002 • 2,045 citations

A Serum Shock Induces Circadian Gene Expression in Mammalian Tissue Culture Cells

1998 • 1,954 citations

Role of the CLOCK Protein in the Mammalian Circadian Mechanism

1998 • 1,915 citations

Resetting Central and Peripheral Circadian Oscillators in Transgenic Rats

2000 • 1,844 citations

mCRY1 and mCRY2 Are Essential Components of the Negative Limb of the Circadian Clock Feedback Loop

1999 • 1,558 citations

Mop3 Is an Essential Component of the Master Circadian Pacemaker in Mammals

2000 • 1,523 citations

Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms

1999 • 1,361 citations

Interacting Molecular Loops in the Mammalian Circadian Clock

2000 • 1,332 citations

Posttranslational Mechanisms Regulate the Mammalian Circadian Clock

2001 • 1,113 citations

Temporal Organization: Reflections of a Darwinian Clock-Watcher

1993 • 943 citations

A Differential Response of Two Putative Mammalian Circadian Regulators, mper1and mper2, to Light

1997 • 883 citations

Differential Functions of mPer1, mPer2, and mPer3 in the SCN Circadian Clock

2001 • 876 citations

Nonredundant Roles of the mPer1 and mPer2 Genes in the Mammalian Circadian Clock

2001 • 873 citations

Three period Homologs in Mammals: Differential Light Responses in the Suprachiasmatic Circadian Clock and Oscillating Transcripts Outside of Brain

1998 • 867 citations

Circadian oscillation of a mammalian homologue of the Drosophila period gene

1997 • 782 citations

System-level identification of transcriptional circuits underlying mammalian circadian clocks

2005 • 765 citations

Two period Homologs: Circadian Expression and Photic Regulation in the Suprachiasmatic Nuclei

1997 • 763 citations

RIGUI, a Putative Mammalian Ortholog of the Drosophila period Gene

1997 • 664 citations

NPAS2: An Analog of Clock Operative in the Mammalian Forebrain

2001 • 555 citations

Molecular Genetics of Circadian Rhythms in Mammals

2000 • 541 citations

Bimodal regulation of mPeriod promoters by CREB-dependent signaling and CLOCK/BMAL1 activity

2002 • 529 citations

A noncanonical E-box enhancer drives mouse Period2 circadian oscillations in vivo

2005 • 293 citations

Control of Intracellular Dynamics of Mammalian Period Proteins by Casein Kinase I ε (CKIε) and CKIδ in Cultured Cells

2002 • 282 citations

Nucleocytoplasmic shuttling and mCRY-dependent inhibition of ubiquitylation of the mPER2 clock protein

2002 • 267 citations

A light-independent oscillatory gene mPer3 in mouse SCN and OVLT

1998 • 234 citations

A new mammalian period gene predominantly expressed in the suprachiasmatic nucleus

1998 • 220 citations

CLIF, a Novel Cycle-like Factor, Regulates the Circadian Oscillation of Plasminogen Activator Inhibitor-1 Gene Expression

2000 • 200 citations

Regulation of the PAI-1 promoter by circadian clock components: differential activation by BMAL1 and BMAL2

2003 • 155 citations

Direct Association between Mouse PERIOD and CKIε Is Critical for a Functioning Circadian Clock

2003 • 154 citations

Asynchronous oscillations of two zebrafish CLOCK partners reveal differential clock control and function

2000 • 135 citations

Activation of TGF-β/activin signalling resets the circadian clock through rapid induction of Dec1 transcripts

2008 • 125 citations

Interaction of circadian clock proteins PER2 and CRY with BMAL1 and CLOCK

2008 • 118 citations

The Basic Helix-Loop-Helix-PAS Protein MOP9 Is a Brain-Specific Heterodimeric Partner of Circadian and Hypoxia Factors

2000 • 113 citations

The BMAL1 C terminus regulates the circadian transcription feedback loop

2006 • 110 citations

Structural and functional features of transcription factors controlling the circadian clock

2005 • 101 citations

Chicken pineal clock genes: implication of BMAL2 as a bidirectional regulator in circadian clock oscillation

2001 • 94 citations

Cryptochromes impair phosphorylation of transcriptional activators in the clock: a general mechanism for circadian repression

2007 • 93 citations

Identification of mPer1 Phosphorylation Sites Responsible for the Nuclear Entry

2004 • 75 citations

cDNA Cloning of a Novel bHLH-PAS Transcription Factor Superfamily Gene, BMAL2: Its mRNA Expression, Subcellular Distribution, and Chromosomal Localization

2000 • 55 citations

Cloning of mouse BMAL2 and its daily expression profile in the suprachiasmatic nucleus: a remarkable acceleration of Bmal2 sequence divergence after Bmal gene duplication

2001 • 48 citations

mPER1‐mediated nuclear export of mCRY1/2 is an important element in establishing circadian rhythm

2005 • 10 citations