Role of Cholinesterase Inhibitors in Parkinson’s Disease and dementia with Lewy Bodies

Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB)

1996 • 3,940 citations

Efficacy of rivastigmine in dementia with Lewy bodies: a randomised, double-blind, placebo-controlled international study

2000 • 1,110 citations

Cerebral atrophy in Parkinson's disease with and without dementia: a comparison with Alzheimer's disease, dementia with Lewy bodies and controls

2004 • 624 citations

Neuroleptic sensitivity in patients with senile dementia of Lewy body type.

1992 • 609 citations

Cholinergic correlates of cognitive impairment in Parkinson's disease: comparisons with Alzheimer's disease.

1985 • 570 citations

Cortical Cholinergic Function Is More Severely Affected in Parkinsonian Dementia Than in Alzheimer Disease

2003 • 529 citations

Basal forebrain neurons in the dementia of Parkinson disease

1983 • 526 citations

Synucleinopathy pathology and REM sleep behavior disorder plus dementia or parkinsonism

2003 • 376 citations

In vivo mapping of cholinergic terminals in normal aging, Alzheimer's disease, and Parkinson's disease

1996 • 374 citations

The pedunculopontine nucleus in Parkinson's disease, progressive supranuclear palsy and Alzheimer's disease.

1988 • 364 citations

Donepezil for cognitive impairment in Parkinson's disease: a randomised controlled study

2002 • 345 citations

Comparative Alterations of Nicotinic and Muscarinic Binding Sites in Alzheimer's and Parkinson's Diseases

1992 • 324 citations

Selectivity of Cholinesterase Inhibition

1999 • 271 citations

Rivastigmine in the treatment of parkinsonian psychosis and cognitive impairment: Preliminary findings from an open trial

2001 • 265 citations

Advances in the Treatment of Alzheimer’s Disease: Benefits of Dual Cholinesterase Inhibition

2002 • 246 citations

Randomized placebo‐controlled trial of donepezil in cognitive impairment in Parkinson's disease

2004 • 230 citations

Donepezil for Treatment of Dementia With Lewy Bodies: A Case Series of Nine Patients

1998 • 226 citations

Increased Alzheimer pathology in Parkinson's disease related to antimuscarinic drugs

2003 • 222 citations

Cognitive, psychiatric and motor response to galantamine in Parkinson's disease with dementia

2003 • 216 citations

Cholinergic Transmitter and Neurotrophic Activities in Lewy Body Dementia

1993 • 212 citations

Effects of Rivastigmine on Cognitive Function in Dementia with Lewy Bodies: A Randomised Placebo-Controlled International Study Using the Cognitive Drug Research Computerised Assessment System

2002 • 205 citations

Evidence of a Monoaminergic‐Cholinergic Imbalance Related to Visual Hallucinations in Lewy Body Dementia

1990 • 201 citations

The effects of nicotine on Parkinson's disease.

2000 • 175 citations

Better cognitive and psychopathologic response to donepezil in patients prospectively diagnosed as dementia with Lewy bodies: a preliminary study

2000 • 173 citations

Dementia with Lewy Bodies Versus Pure Alzheimer Disease

1997 • 165 citations

Nicotinic Acetylcholine Receptor Distribution in Alzheimer's Disease, Dementia with Lewy Bodies, Parkinson's Disease, and Vascular Dementia: In Vitro Binding Study Using 5-[125I]-A-85380

2003 • 165 citations

Early and Widespread Cholinergic Losses Differentiate Dementia With Lewy Bodies From Alzheimer Disease

2002 • 161 citations

Rivastigmine for the Treatment of Dementia and Visual Hallucinations Associated with Parkinson's Disease: A Case Series

2002 • 159 citations

Extrapyramidal features in Parkinson's disease with and without dementia and dementia with Lewy bodies: A cross‐sectional comparative study

2003 • 158 citations

Nicotine may relieve symptoms of Parkinson's disease

1994 • 158 citations

Chronic effects of dopaminergic replacement on cognitive function in Parkinson's disease: A two-year follow-up study of previously untreated patients

2000 • 157 citations

Delusions associated with elevated muscarinic binding in dementia with Lewy bodies

2000 • 156 citations

Nicotine binding in human striatum: elevation in schizophrenia and reductions in dementia with Lewy bodies, Parkinson’s disease and Alzheimer’s disease and in relation to neuroleptic medication

2000 • 155 citations

Successful Use of Donepezil for the Treatment of Psychotic Symptoms in Patients With Parkinson's Disease

2002 • 155 citations

Rivastigmine in the treatment of dementia with Lewy bodies: preliminary findings from an open trial

2000 • 153 citations

Donepezil in the treatment of hallucinations and delusions in Parkinson’s disease

2002 • 152 citations

Long-Term Use of Rivastigmine in Patients With Dementia With Lewy Bodies: An Open-Label Trial

2001 • 134 citations

Transdermal nicotine in PD

2001 • 130 citations

What happens when donepezil is suddenly withdrawn? An open label trial in dementia with Lewy bodies and Parkinson's disease with dementia

2003 • 126 citations

The decline in synapses and cholinergic activity is asynchronous in Alzheimer’s disease

2000 • 121 citations

Dementia with Lewy bodies: choline acetyltransferase parallels nucleus basalis pathology

1999 • 110 citations

Rivastigmine (Exelon) for dementia in patients with Parkinson's disease

2003 • 91 citations

The beneficial effect of cholinesterase inhibitors on patients suffering from Parkinson's disease and dementia

2001 • 91 citations

Regulation of attention and response to therapy in dementia by butyrylcholinesterase

2003 • 87 citations

Dementia With Lewy Bodies Treated With Rivastigmine: Effects on Cognition, Neuropsychiatric Symptoms, and Sleep

2001 • 82 citations

Increased Levels of Tau Protein in SH‐SY5Y Cells After Treatment with Cholinesterase Inhibitors and Nicotinic Agonists

2000 • 76 citations

Butyrylcholinesterase and progression of cognitive deficits in dementia with Lewy bodies

2003 • 72 citations

Pathology and Neurotransmitter Abnormalities of Dementia with Lewy Bodies

2003 • 71 citations

Muscarinic receptors in basal ganglia in dementia with Lewy bodies, Parkinson's disease and Alzheimer's disease

2003 • 65 citations

Efficacy and Safety of Galantamine in Patients with Dementia with Lewy Bodies: A 12-Week Interim Analysis

2003 • 65 citations

The Beneficial Effect of Donepezil on Visual Hallucinations in Three Patients with Parkinson's Disease

2003 • 61 citations

Visual hallucinations are associated with lower αbungarotoxin binding in dementia with Lewy bodies

2001 • 53 citations

Nicotinic receptor losses in dementia with Lewy bodies: comparisons with Alzheimer's disease

2000 • 46 citations

Tacrine efficacy in Lewy body dementia

1998 • 42 citations

Acetylcholinesterase Inhibition in Dementia with Lewy Bodies: Results of a Prospective Pilot Trial

2000 • 41 citations

Disturbances of consciousness in dementia with Lewy bodies associated with alteration in nicotinic receptor binding in the temporal cortex

2002 • 35 citations

Acetyl- and butyrylcholinesterase activity in the cerebrospinal fluid of patients with Parkinson's disease

1987 • 24 citations

Severe worsening of parkinsonism in Lewy body dementia due to donepezil

2003 • 15 citations