Influence of human genome polymorphism on gene expression

Initial sequencing and analysis of the human genome

2001 • 23,520 citations

A haplotype map of the human genome

2005 • 5,856 citations

The Future of Genetic Studies of Complex Human Diseases

1996 • 5,355 citations

The ENCODE (ENCyclopedia Of DNA Elements) Project

2004 • 2,327 citations

Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease

2003 • 1,925 citations

Genetics of gene expression surveyed in maize, mouse and man

2003 • 1,518 citations

Genome-Wide Survey of Human Alternative Pre-mRNA Splicing with Exon Junction Microarrays

2003 • 1,406 citations

Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer

2001 • 1,297 citations

Genetic analysis of genome-wide variation in human gene expression

2004 • 1,219 citations

Fine-scale structural variation of the human genome

2005 • 1,001 citations

Trans-acting regulatory variation in Saccharomyces cerevisiae and the role of transcription factors

2003 • 639 citations

Allelic Variation in Human Gene Expression

2002 • 622 citations

Mapping determinants of human gene expression by regional and genome-wide association

2005 • 598 citations

Centre d'Etude du polymorphisme humain (CEPH): Collaborative genetic mapping of the human genome

1990 • 595 citations

Genome-Wide Associations of Gene Expression Variation in Humans

2005 • 521 citations

Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease

2005 • 516 citations

Abundant Raw Material for Cis-Regulatory Evolution in Humans

2002 • 377 citations

Genetic Inheritance of Gene Expression in Human Cell Lines

2004 • 359 citations

The quantitative genetics of transcription

2005 • 330 citations

Cis-Acting Regulatory Variation in the Human Genome

2004 • 269 citations

A survey of genetic and epigenetic variation affecting human gene expression

2004 • 267 citations

Comprehensive analysis of transcriptional promoter structure and function in 1% of the human genome

2005 • 266 citations

In vivo characterization of regulatory polymorphisms by allele-specific quantification of RNA polymerase loading

2003 • 251 citations

Conserved noncoding sequences are selectively constrained and not mutation cold spots

2005 • 238 citations

Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits

2005 • 218 citations

Local Regulatory Variation in Saccharomyces cerevisiae

2005 • 164 citations

Genetical genomics in humans and model organisms

2005 • 140 citations

Survey of allelic expression using EST mining

2005 • 134 citations

Gene expression variation and expression quantitative trait mapping of human chromosome 21 genes

2005 • 108 citations

Allele-specific repression of lymphotoxin-α by activated B cell factor-1

2004 • 102 citations

Mapping common regulatory variants to human haplotypes

2005 • 89 citations

Functional genomics of membrane transporters in human populations

2005 • 53 citations

Prospects and pitfalls in whole genome association studies

2005 • 50 citations

In Silico Study of Transcriptome Genetic Variation in Outbred Populations

2004 • 35 citations

Clonal evolution in human lymphoblast cultures.

1988 • 33 citations

Elucidating cis- and trans-regulatory variation using genetical genomics

2006 • 29 citations

Maternal and Paternal Chromosomes 7 Show Differential Methylation of Many Genes in Lymphoblast DNA

2001 • 26 citations

Allelic variation in gene expression identified through computational analysis of the dbEST database

2005 • 14 citations