Novel Lipid Mediator Regulators of Endothelial Cell Proliferation and Migration: Aspirin-Triggered-15R-Lipoxin A₄and Lipoxin A₄

Angiogenesis in cancer, vascular, rheumatoid and other disease

1995 • 7,717 citations

Angiogenesis.

1992 • 2,581 citations

Vascular Endothelial Growth Factor Regulates Endothelial Cell Survival through the Phosphatidylinositol 3′-Kinase/Akt Signal Transduction Pathway

1998 • 1,963 citations

Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: Insight into mechanisms and implications for cancer growth and ulcer healing

1999 • 830 citations

Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions.

1995 • 694 citations

The role of αv integrins during angiogenesis: insights into potential mechanisms of action and clinical development

1999 • 651 citations

Induction of vascular endothelial growth factor expression in synovial fibroblasts by prostaglandin E and interleukin‐1: a potential mechanism for inflammatory angiogenesis

1995 • 565 citations

Genetic Evidence for Functional Redundancy of Platelet/Endothelial Cell Adhesion Molecule-1 (PECAM-1): CD31-Deficient Mice Reveal PECAM-1-Dependent and PECAM-1-Independent Functions

1999 • 430 citations

Aspirin-triggered 15-Epi-Lipoxin A4 (LXA4) and LXA4 Stable Analogues Are Potent Inhibitors of Acute Inflammation: Evidence for Anti-inflammatory Receptors

1997 • 427 citations

A critical assessment of the use of microculture tetrazolium assays to measure cell growth and function.

1995 • 325 citations

Lipoxins and novel aspirin-triggered 15-epi-lipoxins (ATL): A jungle of cell-cell interactions or a therapeutic opportunity?

1997 • 243 citations

Lipoxin A4 Inhibits IL-1β-Induced IL-6, IL-8, and Matrix Metalloproteinase-3 Production in Human Synovial Fibroblasts and Enhances Synthesis of Tissue Inhibitors of Metalloproteinases

2000 • 216 citations

Local and systemic delivery of a stable aspirin-triggered lipoxin prevents neutrophil recruitmentin vivo

1999 • 209 citations

Migration of leukocytes across endothelium and beyond: molecules involved in the transmigration and fate of monocytes

1999 • 204 citations

Lipoxin (LX)A4 and Aspirin-triggered 15-epi-LXA4 Inhibit Tumor Necrosis Factor 1α–initiated Neutrophil Responses and Trafficking: Regulators of a Cytokine–Chemokine Axis

1999 • 198 citations

Aspirin-Triggered Lipoxins (15-epi-LX) Are Generated by the Human Lung Adenocarcinoma Cell Line (A549)–Neutrophil Interactions and Are Potent Inhibitors of Cell Proliferation

1996 • 189 citations

Cyclooxygenase Gene Expression in Inflammation and Angiogenesis^a

1993 • 169 citations

Selectivity of Recombinant Human Leukotriene D4, Leukotriene B4, and Lipoxin A4 Receptors with Aspirin-Triggered 15-epi-LXA4 and Regulation of Vascular and Inflammatory Responses

2001 • 167 citations

Pathogen-induced chemokine secretion from model intestinal epithelium is inhibited by lipoxin A4 analogs.

1998 • 162 citations

COX‐2 Inhibitors: A New Class of Antiangiogenic Agents

1999 • 155 citations

Transfection of rat kidney with human 15-lipoxygenase suppresses inflammation and preserves function in experimental glomerulonephritis

1999 • 149 citations

Eicosanoid regulation of angiogenesis: role of endothelial arachidonate 12-lipoxygenase

2000 • 134 citations

Prostaglandins Induce Vascular Endothelial Growth Factor in a Human Monocytic Cell Line and Rat Lungs via cAMP

1997 • 127 citations

Lipoxin A4 Antagonizes the Mitogenic Effects of Leukotriene D4 in Human Renal Mesangial Cells

2000 • 119 citations

Aspirin-triggered 15-epi-lipoxin A4 (ATL) generation by human leukocytes and murine peritonitis exudates: development of a specific 15-epi-LXA4 ELISA.

1998 • 103 citations

Aspirin and other anti-inflammatory drugs

2000 • 89 citations

Angiogenesis and Neoplastic Progression In Vitro<xref ref-type="fn" rid="fn2">2</xref>

1982 • 86 citations

The pharmacological modulation of angiogenesis in chronic granulomatous inflammation.

1995 • 77 citations

The role of NF-kappaB in the angiogenic response of coronary microvessel endothelial cells.

1996 • 72 citations

Effects of mutant p53 expression on human 15-lipoxygenase-promoter activity and murine 12/15-lipoxygenase gene expression: Evidence that 15-lipoxygenase is a mutator gene

1999 • 50 citations

Aspirin-triggered 15-epi-lipoxin A4 (ATL) generation by human leukocytes and murine peritonitis exudates: Development of a specific 15-epi-LXA4 ELISA

1999 • 27 citations

Angiogenesis

1999 • 4 citations