Large-scale characterization of HeLa cell nuclear phosphoproteins

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

1996 • 8,994 citations

An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database

1994 • 6,412 citations

Stable Isotope Labeling by Amino Acids in Cell Culture, SILAC, as a Simple and Accurate Approach to Expression Proteomics

2002 • 5,545 citations

Large-scale analysis of the yeast proteome by multidimensional protein identification technology

2001 • 4,766 citations

Stop and Go Extraction Tips for Matrix-Assisted Laser Desorption/Ionization, Nanoelectrospray, and LC/MS Sample Pretreatment in Proteomics

2002 • 2,548 citations

Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae

2002 • 1,646 citations

Evaluation of Multidimensional Chromatography Coupled with Tandem Mass Spectrometry (LC/LC−MS/MS) for Large-Scale Protein Analysis: The Yeast Proteome

2002 • 1,644 citations

Scansite 2.0: proteome-wide prediction of cell signaling interactions using short sequence motifs

2003 • 1,587 citations

A proteomics approach to understanding protein ubiquitination

2003 • 1,577 citations

One‐thousand‐and‐one substrates of protein kinase CK2?

2003 • 1,292 citations

Mass Spectrometry in Proteomics

2001 • 1,236 citations

Development of Human Protein Reference Database as an Initial Platform for Approaching Systems Biology in Humans

2003 • 1,114 citations

Accurate quantitation of protein expression and site-specific phosphorylation

1999 • 1,014 citations

Analysis of protein phosphorylation using mass spectrometry: deciphering the phosphoproteome

2002 • 893 citations

A two-dimensional quadrupole ion trap mass spectrometer

2002 • 773 citations

Enrichment analysis of phosphorylated proteins as a tool for probing the phosphoproteome

2001 • 771 citations

A systematic approach to the analysis of protein phosphorylation

2001 • 720 citations

Proteomics: the move to mixtures

2001 • 628 citations

A Structural Basis for Substrate Specificities of Protein Ser/Thr Kinases: Primary Sequence Preference of Casein Kinases I and II, NIMA, Phosphorylase Kinase, Calmodulin-Dependent Kinase II, CDK5, and Erk1

1996 • 555 citations

Large-scale Analysis of in Vivo Phosphorylated Membrane Proteins by Immobilized Metal Ion Affinity Chromatography and Mass Spectrometry

2003 • 543 citations

Phosphoproteome Analysis of Capacitated Human Sperm

2003 • 473 citations

A Mass Spectrometry-based Proteomic Approach for Identification of Serine/Threonine-phosphorylated Proteins by Enrichment with Phospho-specific Antibodies

2002 • 387 citations

Analysis of phosphorylated proteins and peptides by mass spectrometry

2001 • 382 citations

Detection of Tyrosine Phosphorylated Peptides by Precursor Ion Scanning Quadrupole TOF Mass Spectrometry in Positive Ion Mode

2001 • 299 citations

Signaling by dual specificity kinases

1998 • 291 citations

Improved β-Elimination-Based Affinity Purification Strategy for Enrichment of Phosphopeptides

2003 • 231 citations

Utilization of Oriented Peptide Libraries to Identify Substrate Motifs Selected by ATM

2000 • 190 citations

Analysis of Protein Phosphorylation by a Combination of Elastase Digestion and Neutral Loss Tandem Mass Spectrometry

2000 • 178 citations

A Multidimensional Electrospray MS-Based Approach to Phosphopeptide Mapping

2000 • 165 citations

Cation-exchange chromatography of peptides on poly(2-sulfoethyl aspartamide)-silica

1988 • 137 citations

Hitting the Target: Emerging Technologies in the Search for Kinase Substrates

2002 • 107 citations

Identification of Tyr438 as the major in vitro c‐Src phosphorylation site in human gelsolin: A mass spectrometric approach

1999 • 58 citations

Mapping phosphorylation sites in proteins by mass spectrometry

2002 • 34 citations