Posttraumatic therapeutic vaccination with modified myelin self-antigen prevents complete paralysis while avoiding autoimmune disease

A Sensitive and Reliable Locomotor Rating Scale for Open Field Testing in Rats

1995 • 4,199 citations

Graded Histological and Locomotor Outcomes after Spinal Cord Contusion Using the NYU Weight-Drop Device versus Transection

1996 • 1,440 citations

Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys

1997 • 1,147 citations

Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy

1999 • 881 citations

Encephalitogenic potential of the myelin basic protein peptide (amino acids 83–99) in multiple sclerosis: Results of a phase II clinical trial with an altered peptide ligand

2000 • 805 citations

Implantation of stimulated homologous macrophages results in partial recovery of paraplegic rats

1998 • 794 citations

Altered Peptide Ligand–Induced Partial T Cell Activation: Molecular Mechanisms and Role in T Cell Biology

1996 • 698 citations

Induction of a non-encephalitogenic type 2 T helper-cell autoimmune response in multiple sclerosis after administration of an altered peptide ligand in a placebo-controlled, randomized phase II trial

2000 • 506 citations

An altered peptide ligand mediates immune deviation and prevents autoimmune encephalomyelitis

1995 • 422 citations

Systemically Administered Interleukin-10 Reduces Tumor Necrosis Factor-Alpha Production and Significantly Improves Functional Recovery Following Traumatic Spinal Cord Injury in Rats

1999 • 404 citations

Endogenous Repair after Spinal Cord Contusion Injuries in the Rat

1997 • 398 citations

Passive or Active Immunization with Myelin Basic Protein Promotes Recovery from Spinal Cord Contusion

2000 • 368 citations

Protective Autoimmunity Is a Physiological Response to CNS Trauma

2001 • 349 citations

Innate and adaptive immune responses can be beneficial for CNS repair

1999 • 336 citations

The effects of methylprednisolone and the ganglioside GM1 on acute spinal cord injury in rats

1994 • 330 citations

T cell immunity to copolymer 1 confers neuroprotection on the damaged optic nerve: Possible therapy for optic neuropathies

2000 • 312 citations

Vaccination for protection of retinal ganglion cells against death from glutamate cytotoxicity and ocular hypertension: Implications for glaucoma

2001 • 293 citations

A Therapeutic Vaccine Approach to Stimulate Axon Regeneration in the Adult Mammalian Spinal Cord

1999 • 289 citations

Experimental autoimmune encephalomyelitis (EAE) mediated by T cell lines: process of selection of lines and characterization of the cells.

1982 • 261 citations

Modulation of cytokine patterns of human autoreactive T cell clones by a single amino acid substitution of their peptide ligand

1995 • 236 citations

Neuronal Survival after CNS Insult Is Determined by a Genetically Encoded Autoimmune Response

2001 • 231 citations

Apoptosis in Cellular Compartments of Rat Spinal Cord After Severe Contusion Injury

1998 • 203 citations

Mediators of Injury in Neurotrauma: Intracellular Signal Transduction and Gene Expression

1995 • 194 citations

Autoimmunity can benefit self-maintenance

2000 • 190 citations

Modeling of Acute Spinal Cord Injury in the Rat: Neuroprotection and Enhanced Recovery with Methylprednisolone, U-74006F and YM-14673

1994 • 186 citations

Experimental neurobiology of central nervous system trauma.

1993 • 167 citations

A single amino acid change in a myelin basic protein peptide confers the capacity to prevent rather than induce experimental autoimmune encephalomyelitis.

1991 • 165 citations

Protective autoimmunity: regulation and prospects for vaccination after brain and spinal cord injuries

2001 • 164 citations

Vaccination for Neuroprotection in the Mouse Optic Nerve: Implications for Optic Neuropathies

2001 • 156 citations

Neuroprotective Effects of Interleukin-10 Following Excitotoxic Spinal Cord Injury

1999 • 150 citations

Diffusion anisotropy MRI for quantitative assessment of recovery in injured rat spinal cord

2001 • 137 citations

The Effects of FK506 on Dorsal Column Axons Following Spinal Cord Injury in Adult Rats: Neuroprotection and Local Regeneration

1999 • 128 citations

Amelioration of relapsing experimental autoimmune encephalomyelitis with altered myelin basic protein peptides involves different cellular mechanisms

1997 • 120 citations

Morphological aspects of spinal cord autoimmune neuroprotection: colocalization of T cells with B7–2 (CD86) and prevention of cyst formation

2001 • 111 citations

Hydroxyl Radicals Generated In Vivo Kill Neurons in the Rat Spinal Cord: Electrophysiological, Histological, and Neurochemical Results

1994 • 110 citations

Differential activation of human autoreactive T cell clones by altered peptide ligands derived from myelin basic protein peptide (87–99)

1996 • 95 citations

Heteroclitic proliferative responses and changes in cytokine profile induced by altered peptides: Implications for autoimmunity

1998 • 80 citations

Autoimmune maintenance and neuroprotection of the central nervous system

1999 • 79 citations

T-cell-based immunity counteracts the potential toxicity of glutamate in the central nervous system

2001 • 71 citations

Autoimmune effector cells. III. Role of adjuvant and accessory cells in the in vitro induction of autoimmune encephalomyelitis.

1982 • 23 citations

Transfer of allergic encephalomyelitis with spleen cells from donors sensitized with myelin basic protein in incomplete Freund's adjuvant.

1982 • 22 citations