Abnormal Splenic and Thymic IL‐4 and TNF‐α Expression in MRL‐lpr/lpr Mice

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains.

1978 • 1,619 citations

Tumour necrosis factor-α in murine autoimmune 'lupus' nephritis

1988 • 599 citations

AMPLIFICATION OF RNA

1990 • 486 citations

Defective production of interleukin 1 and interleukin 2 in patients with systemic lupus erythematosus (SLE).

1983 • 453 citations

Decreased production of and response to interleukin-2 by cultured lymphocytes from patients with systemic lupus erythematosus.

1982 • 421 citations

Increased tumor necrosis factor and IL-1 beta gene expression in the kidneys of mice with lupus nephritis.

1988 • 321 citations

Systemic autoimmune disease arises from polyclonal B cell activation.

1987 • 314 citations

A spontaneous rheumatoid arthritis-like disease in MRL/l mice.

1982 • 303 citations

Glomerular cell culture.

1985 • 298 citations

Tumor necrosis factor and IL-1 in New Zealand Black/White mice. Enhanced gene expression and acceleration of renal injury.

1989 • 255 citations

In vivo cytokine gene expression in T cell subsets of the autoimmune MRL/Mp‐lpr/lpr mouse

1990 • 219 citations

Interleukin 2 deficiency is a common feature of autoimmune mice.

1981 • 198 citations

Chronic therapy with recombinant tumor necrosis factor-α in autoimmune NZB/NZW F1 mice

1989 • 169 citations

Recovery from autoimmunity of MRL/lpr mice after infection with an interleukin-2/vaccinia recombinant virus

1990 • 140 citations

Tumor necrosis factor α in autoimmunity: pretty girl or old witch?

1992 • 128 citations

Novel and enhanced IL-1 gene expression in autoimmune mice with lupus.

1988 • 126 citations

Abnormal Production of and Response to B‐Cell Growth Factor and B‐Cell Differentiation Factor in Patients with Systemic Lupus Erythematosus

1985 • 44 citations

Characterization of cytokine gene expression in CD4+ and CD8+ T cells after activation with phorbol myristate acetate and phytohaemagglutinin

1992 • 41 citations

0KT3‐Induced Cytokine mRNA Expression in Human Peripheral Blood Mononuclear Cells Measured by Polymerase Chain Reaction

1992 • 31 citations

Suppression of renal disease and arthritis, and prolongation of survival in MRL‐lpr mice treated with an extract of tripterygium wilfordii hook F

1992 • 29 citations

Imbalanced cytokine production by macrophages from autoimmune-prone mice

1991 • 28 citations

Effect of antibodies to double stranded DNA, purified from serum samples of patients with active systemic lupus erythematosus, on the glomerular mesangial cells.

1992 • 27 citations

Increased excretion of soluble interleukin 2 receptors and free light chain immunoglobulins in the urine of patients with active lupus nephritis.

1992 • 25 citations

Monoclonal antibodies against human recombinant tumor necrosis factor: prevention of endotoxic shock

1988 • 25 citations

Elevated production of interleukin 6 by hepatic MNC correlates with ICAM-1 expression on the hepatic sinusoidal endothelial cells in autoimmune MRL/lpr mice

1993 • 22 citations

Mesangial cell immune injury. Hemodynamic role of leukocyte- and platelet-derived eicosanoids.

1992 • 21 citations

Evidence for a mouse mesangial cell-derived factor that stimulates lymphocyte proliferation.

1985 • 18 citations

Software for the quantitative evaluation of in vitro monoclonal antibody production from ELISA data

1987 • 15 citations

Cultured mesangial cells from autoimmune MRL-lpr mice have decreased secreted and surface M-CSF

1992 • 13 citations

Regulation of B cell activation in autoimmune mice

1989 • 11 citations

The role of the interleukin‐2 (IL‐2)/IL‐2 receptor pathway in MRL/lpr lymphadenopathy: The expanded CD4⁻8⁻ T cell subset completely lacks functional IL‐2 receptors

1993 • 11 citations

Biosynthesis of Colony-Stimulating Factor-1 (CSF-1) by Mesangial Cells of Autoimmune Mice

1993 • 5 citations