Role of interferon alpha in promoting T helper cell type 1 responses in the small intestine in coeliac disease

Inflammatory bowel disease: Etiology and pathogenesis

1998 • 2,095 citations

Signals and signs for lymphocyte responses

1994 • 868 citations

Cytokine therapeutics: lessons from interferonalpha.

1994 • 703 citations

Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells

1997 • 582 citations

Gluten induces an intestinal cytokine response strongly dominated by interferon gamma in patients with celiac disease

1998 • 460 citations

Evidence that activated mucosal T cells play a role in the pathogenesis of enteropathy in human small intestine.

1988 • 404 citations

Bioactive IL-18 Expression Is Up-Regulated in Crohn’s Disease

1999 • 399 citations

Cross Talk Between Interferon-γ and -α/β Signaling Components in Caveolar Membrane Domains

2000 • 316 citations

Induction of Type I Diabetes by Interferon-α in Transgenic Mice

1993 • 289 citations

Cyclooxygenase-2-dependent arachidonic acid metabolites are essential modulators of the intestinal immune response to dietary antigen

1999 • 272 citations

Interferon‐β mediates stromal cell rescue of T cells from apoptosis

1999 • 194 citations

Immunomodulation and Therapeutic Effects of the Oral Use of Interferon-alpha: Mechanism of Action

1999 • 134 citations

T cells orchestrate intestinal mucosal shape and integrity

1999 • 126 citations

Functional expression of Fas and Fas ligand on human gut lamina propria T lymphocytes. A potential role for the acidic sphingomyelinase pathway in normal immunoregulation.

1996 • 124 citations

The pathogenesis of celiac disease

1998 • 115 citations

IFN-β-1b Inhibits IL-12 Production in Peripheral Blood Mononuclear Cells in an IL-10-Dependent Mechanism: Relevance to IFN-β-1b Therapeutic Effects in Multiple Sclerosis

2000 • 107 citations

T-cell activation can induce either mucosal destruction or adaptation in cultured human fetal small intestine

1993 • 100 citations

IFN-alpha induces autoimmune T cells through the induction of intracellular adhesion molecule-1 and B7.2.

1996 • 96 citations

Human Peyer’s Patch T Cells Are Sensitized to Dietary Antigen and Display a Th Cell Type 1 Cytokine Profile

2000 • 92 citations

Interactions between stromal cell--derived keratinocyte growth factor and epithelial transforming growth factor in immune-mediated crypt cell hyperplasia.

1998 • 78 citations

Interferon-α Therapy Associated With the Development of Sarcoidosis

1999 • 77 citations

Inflammatory bowel disease: Etiology and pathogenesis

1999 • 72 citations

T cell immunity to oral allergens

1998 • 64 citations

Alpha-interferon inhibits the development of diabetes in NOD mice.

1998 • 52 citations

Ingested IFN-α has biological effects in humans with relapsing-remitting multiple sclerosis

1997 • 46 citations

Rescue by cytokines of apoptotic cell death induced by IL-2 deprivation of human antigen-specific T cell clones

1997 • 38 citations

Bioactive interleukin-18 expression is up-regulated in Crohn’s disease

1999 • 9 citations