CORRELATIONS BETWEEN THE RATE OF INTRACELLULAR RELEASE OF ENDOCYTOSED LIPOSOMAL DOXORUBICIN AND CYTOTOXICITY AS DETERMINED BY A NEW ASSAY

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1983 • 52,849 citations

Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo

1991 • 1,370 citations

たんぱく質‐色素結合の原理を用いるμg量のたんぱく質の定量のための迅速,高感度法

1976 • 752 citations

Nuclear delivery of doxorubicin via folate-targeted liposomes with bypass of multidrug-resistance efflux pump.

2000 • 401 citations

Doxorubicin Encapsulated in Liposomes Containing Surface‐Bound Polyethylene Glycol: Pharmacokinetics, Tumor Localization, and Safety in Patients with AIDS‐Related Kaposi's Sarcoma

1996 • 370 citations

In vitro and in vivo targeting of immunoliposomal doxorubicin to human B-cell lymphoma.

1998 • 260 citations

Phase I/II clinical and pharmacokinetic evaluation of liposomal daunorubicin.

1995 • 243 citations

Deciphering the fluorescence signature of daunomycin and doxorubicin

1998 • 204 citations

Liposomes with detachable polymer coating: destabilization and fusion of dioleoylphosphatidylethanolamine vesicles triggered by cleavage of surface‐grafted poly(ethylene glycol)

1996 • 203 citations

Ammonium Sulfate Gradients for Efficient and Stable Remote Loading of Amphipathic Weak Bases into Liposomes and Ligandoliposomes.

1994 • 195 citations

Initial clinical (phase I) trial of TLC D-99 (doxorubicin encapsulated in liposomes).

1993 • 137 citations

Cytoplasmic delivery of calcein mediated by liposomes modified with a pH-sensitive poly(ethylene glycol) derivative

1997 • 130 citations

Membrane contact, fusion and hexagonal (HII) transitions in phosphatidylethanolamine liposomes

1990 • 109 citations

Quantitative study of doxorubicin in living cell nuclei by microspectrofluorometry

1988 • 106 citations

Copolymers of N‐isopropylacrylamide can trigger pH sensitivity to stable liposomes

1998 • 105 citations

Use of radiolabeled hexadecyl cholesteryl ether as a liposome marker

1982 • 86 citations

Determination of Free and Liposome-Associated Doxorubicin and Vincristine Levels in Plasma under Equilibrium Conditions Employing Ultrafiltration Techniques

1995 • 80 citations

pH-Sensitive Liposomes

1994 • 77 citations

Effect of cholesterol and charge on pore formation in bilayer vesicles by a pH-sensitive peptide

1996 • 72 citations

Doxorubicin resistance in P388 leukemia—evidence for reduced drug influx

1989 • 72 citations

Cellular Trafficking and Cytotoxicity of Anti-Cd19-Targeted Liposomal Doxorubicin in B Lymphoma Cells

1999 • 71 citations

Method for rapid separation of liposome-associated doxorubicin from free doxorubicin in plasma

1990 • 52 citations

pH-Induced destabilization of lipid bilayers by a lipopeptide derived from influenza hemagglutinin

1997 • 48 citations

Room temperature phosphorescence optosensor for anthracyclines

1998 • 20 citations

Kinetics of anthracycline accumulation in multidrug-resistant tumor cells: relationship to drug lipophilicity and serum albumin binding

1998 • 19 citations

Direct evaluation of intracellular accumulation of free and polymer-bound anthracyclines

1995 • 17 citations

Intracellular pharmacokinetics of anthracyclines in human leukemia cells: correlation of DNA-binding with apoptotic cell death.

1998 • 17 citations

Accumulation, metabolism and subcellular localization of daunorubicin, doxorubicin and their DNA-complexes in rat heart ventricles

1981 • 15 citations

Comparison of the intracellular pharmacokinetics of doxorubicin and 4?-epi-doxorubicin in patients with acute leukemia

1989 • 15 citations

Quantition of cell-associated doxorubicin by high-performance liquid chromatography after enzymatic desequestration

1994 • 10 citations

Quantitative evaluation of intracellular uptake of daunorubicin in acute myeloid leukemia: A method analysis

1986 • 8 citations

Quantitative determination of adriamycin in rat hepatocytes using a volatile extraction buffer, HPLC and fluorescence detection

1987 • 4 citations

Qualitatively Different Mechanisms of Resistance to Doxorubicin, Both Involving Altered Glutathione Pools, in two Myeloid Cell Lines in Vitro

1995 • 1 citations