Massive acinar cell apoptosis with secondary necrosis, origin of ducts in atrophic lobules and failure to regenerate in cyanohydroxybutene pancreatopathy in rats

Cell Death: The Significance of Apoptosis

1980 • 7,281 citations

A formaldehyde - glutaraldehyde fixative of high osmolarity for use in electron microscopy

1965 • 5,954 citations

A formaldehyde-glutaraldehyde fixative of high osmolality for use in electron-microscopy

1965 • 5,043 citations

Lethal effect of the anti-Fas antibody in mice

1993 • 1,915 citations

Cell death and control of cell survival in the oligodendrocyte lineage

1992 • 1,331 citations

In situ detection of fragmented dna (tunel assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: A cautionary note

1995 • 1,171 citations

A Second Pathway for Regeneration of Adult Exocrine and Endocrine Pancreas: A Possible Recapitulation of Embryonic Development

1993 • 650 citations

In situ end‐labelling detects DNA strand breaks in apoptosis and other physiological and pathological states

1993 • 584 citations

Chapter 1 Anatomical Methods in Cell Death

1995 • 475 citations

Genes required for the engulfment of cell corpses during programmed cell death in Caenorhabditis elegans.

1991 • 463 citations

In situ detection of fragmented DNA (tunel assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: A cautionary note*1

1995 • 453 citations

Large-scale normal cell death in the developing rat kidney and its reduction by epidermal growth factor

1993 • 433 citations

Relationship between severity, necrosis, and apoptosis in five models of experimental acute pancreatitis

1995 • 302 citations

Microfilament-disrupting agents prevent the formation of apoptotic bodies in tumor cells undergoing apoptosis.

1992 • 250 citations

The Role of Apoptosis in the Response of Cells and Tumours to Mild Hyperthermia

1991 • 176 citations

Course and spontaneous regression of acute pancreatitis in the rat

1979 • 171 citations

Apoptosis during macrophage-dependent ocular tissue remodelling

1994 • 166 citations

Cell death and cell proliferation during atrophy of the rat parotid gland induced by duct obstruction

1987 • 147 citations

Transitional cells in the regenerating pancreas

1994 • 142 citations

The importance of oxidative stress in apoptosis

1997 • 138 citations

Time Course and Cellular Source of Pancreatic Regeneration Following Acute Pancreatitis in the Rat

1986 • 138 citations

Intermediate filaments as differentiation markers of normal pancreas and pancreas cancer.

1992 • 126 citations

Toxicology of glucosinolates, related compounds (nitriles, R-goitrin, isothiocyanates) and vitamin U found in cruciferae

1980 • 116 citations

Induction of Apoptosis in Pancreatic Acinar Cells Reduces the Severity of Acute Pancreatitis

1998 • 114 citations

Ultrastructure of the rat pancreas after experimental duct ligation. I. The role of apoptosis and intraepithelial macrophages in acinar cell deletion.

1987 • 114 citations

A Comparison of the Individual and Collective Effects of Four Glucosinolate Breakdown Products from Brussels Sprouts on Induction of Detoxification Enzymes

1998 • 103 citations

The ultrastructural organization of the rat exocrine pancreas

1962 • 103 citations

The significance of cell death by apoptosis in hepatobiliary disease

1987 • 97 citations

Origin of acinar cell regeneration after atrophy of the rat parotid induced by duct obstruction

1998 • 83 citations

Molecular genetics of cell death in the nematode Caenorhabditis elegans

1992 • 77 citations

Concentration of amylase along its secretory pathway in the pancreatic acinar cell as revealed by high resolution immunocytochemistry

1984 • 71 citations

Ultrastructure of the Rat Pancreas after Experimental Duct Ligation. II. Duct and Stromal Cell Proliferation, Differentiation, and Deletion

1992 • 68 citations

Identification of rat pancreatic duct cells by their expression of cytokeratins 7, 19, and 20 in vivo and after isolation and culture.

1995 • 63 citations

The ultrastructural organization of the rat exocrine pancreas

1962 • 62 citations

The ultrastructural organization of the rat exocrine pancreas

1962 • 60 citations

Morphology of the exocrine pancreas related to pancreatitis

1997 • 56 citations

Silyl nitronates, nitrile oxides, and derived 2-isoxazolines in organic synthesis. Functionalization of butadiene, a novel route to furans and 2-isoxazolines as an alternative to aldol-type condensations

1983 • 52 citations

Ethionine-Induced Atrophy of Rat Pancreas Involves Apoptosis of Acinar Cells

1993 • 44 citations

Induction of Apoptosis Reduces the Severity of Caerulein-Induced Pancreatitis in Mice

1996 • 43 citations

Mechanism of pseudoductular (tubular) formation during pancreatic carcinogenesis in the hamster model. An electron-microscopic and immunohistochemical study.

1988 • 40 citations

Redifferentiation and apoptosis of pancreatic cells during acute pancreatitis

1996 • 39 citations

The role of oxygen-derived free radicals in two models of experimental acute pancreatitis: Effects of catalase, superoxide dismutase, dimethylsulfoxide, and allopurinol

1991 • 36 citations

Selective pancreatotoxicity in the rat induced by the naturally occurring plant nitrile 1-cyano-2-hydroxy-3-butene

1988 • 36 citations

Separation of the toxic and glutathione-enhancing effects of the naturally occurring nitrile, cyanohydroxybutene*1

1992 • 35 citations

The problem of the precursor cell of regenerating pancreatic acinar epithelium.

1960 • 35 citations

Demonstration of expanding cell populations in mouse pancreatic acini and islets

1987 • 33 citations

Role of Neutrophils in Cerulein-Induced Pancreatitis in Rats: Possible Involvement of Apoptosis

1997 • 31 citations

Expression of Bcl-2 and PCNA in Duct Cells After Pancreatic Duct Ligation in Rats

1997 • 30 citations

Involution of the pancreas after ligation of the pancreatic ducts. I: a histological study.

1981 • 29 citations

Enhancement of pancreatic and hepatic glutathione levels in rats during cyanohydroxybutene intoxication*1

1990 • 28 citations

Role of apoptosis in copper deficiency-induced pancreatic involution in the rat.

1993 • 28 citations

Streaming pancreas: islet cell kinetics.

1990 • 19 citations

The Exocrine Pancreas and Salivary Glands

1983 • 15 citations

STUDIES ON RAPE‐SEED MEAL AND ITS GOITROGENIC EFFECT ON PIGS

1954 • 13 citations

Analysis of the Derangement of the Pancreatic Microcirculation in a Rat Caerulein Pancreatitis Model Using an Intravital Microscope System.

1996 • 11 citations

The Acute Pancreatotoxic Effects of the Plant Nitrile 1-Cyano-2-hydroxy-3-butene

1991 • 9 citations

Temporal relationship of acinar and microvascular changes in caerulein-induced pancreatitis

1993 • 9 citations

Growth Depressing Factors in Rapeseed Oilmeal1

1953 • 9 citations

Programmed cell death in the anuran tadpole tail requires expression of a cell surface glycoprotein

1996 • 5 citations