A tyrosine-based sorting signal in the beta 2 integrin cytoplasmic domain mediates its recycling to the plasma membrane and is required for ligand-supported migration

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

Cell Migration: A Physically Integrated Molecular Process

1996 • 3,909 citations

Integrins αvβ3 and αvβ5 promote adenovirus internalization but not virus attachment

1993 • 2,182 citations

ENDOCYTOSIS AND MOLECULAR SORTING

1996 • 1,537 citations

Interaction of Tyrosine-Based Sorting Signals with Clathrin-Associated Proteins

1995 • 955 citations

NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor.

1990 • 944 citations

Signal-Dependent Membrane Protein Trafficking in the Endocytic Pathway

1993 • 808 citations

Multiple β1 chain integrins are receptors for invasin, a protein that promotes bacterial penetration into mammalian cells

1990 • 802 citations

CLATHRIN-COATED VESICLE FORMATION AND PROTEIN SORTING: An Integrated Process

1997 • 793 citations

Ca2+- and calcineurin-dependent recycling of an integrin to the front of migrating neutrophils

1995 • 555 citations

Modulation of cell migration by integrin-mediated cytoskeletal linkages and ligand-binding affinity.

1996 • 365 citations

Rho: theme and variations

1996 • 290 citations

Identification of amino acid sequences in the integrin beta 1 cytoplasmic domain implicated in cytoskeletal association

1992 • 285 citations

Sequence requirements for the recognition of tyrosine-based endocytic signals by clathrin AP-2 complexes.

1996 • 272 citations

Mechanisms of phagocytosis

1996 • 265 citations

Regulation of Adhesion to ICAM-1 by the Cytoplasmic Domain of LFA-1 Integrin β Subunit

1991 • 262 citations

In migrating fibroblasts, recycling receptors are concentrated in narrow tubules in the pericentriolar area, and then routed to the plasma membrane of the leading lamella.

1994 • 250 citations

Endocytosis and recycling of the fibronectin receptor in CHO cells.

1989 • 231 citations

Ligand binding regulates the directed movement of β1 integrins on fibroblasts

1996 • 223 citations

Circulating integrins: alpha 5 beta 1, alpha 6 beta 4 and Mac-1, but not alpha 3 beta 1, alpha 4 beta 1 or LFA-1.

1992 • 218 citations

Getting Membrane Flow and the Cytoskeleton to Cooperate in Moving Cells

1996 • 192 citations

Requirement of the NPXY motif in the integrin beta 3 subunit cytoplasmic tail for melanoma cell migration in vitro and in vivo.

1995 • 186 citations

Moving Membrane up to the Front of Migrating Cells

1996 • 167 citations

Membrane traffic during cell locomotion

1998 • 149 citations

Mutation of the Cytoplasmic Domain of the Integrin β3 Subunit

1995 • 144 citations

HUMAN NATURAL KILLER LYMPHOCYTES DIRECTLY RECOGNIZE EVOLUTIONARILY CONSERVED OLIGOSACCHARIDE LIGANDS EXPRESSED BY XENOGENEIC TISSUES1

1997 • 134 citations

Modulation of β1A Integrin Functions by Tyrosine Residues in the β1 Cytoplasmic Domain

1998 • 109 citations

EGF induces recycling membrane to form ruffles

1998 • 82 citations

Activation of Phagocytic Cells' C3 Receptors for Phagocytosis

1985 • 73 citations

Aggregation As a Determinant of Protein Fate in Post-Golgi Compartments: Role of the Luminal Domain of Furin in Lysosomal Targeting

1997 • 66 citations

Integrin cytoplasmic domains as connectors to the cell's signal transduction apparatus

1997 • 59 citations

Conserved regions in the cytoplasmic domains of the leukocyte integrin alpha L beta 2 are involved in endoplasmic reticulum retention, dimerization, and cytoskeletal association.

1995 • 48 citations

Signal-Dependent Membrane Protein Trafficking in the Endocytic Pathway

1993 • 45 citations

Effects of β Subunit Cytoplasmic Domain Deletions on the Recruitment of the Integrin αvβ6 to Focal Contacts

1994 • 26 citations