Characterization of Cell–Matrix Adhesion Requirements for the Formation of Fascin Microspikes

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

Cell Migration: A Physically Integrated Molecular Process

1996 • 3,909 citations

Cell Adhesion: The Molecular Basis of Tissue Architecture and Morphogenesis

1996 • 3,454 citations

SV40-transformed simian cells support the replication of early SV40 mutants

1981 • 2,564 citations

Focal Adhesions: Transmembrane Junctions Between the Extracellular Matrix and the Cytoskeleton

1988 • 2,137 citations

FOCAL ADHESIONS, CONTRACTILITY, AND SIGNALING

1996 • 1,900 citations

Signal transduction from the extracellular matrix.

1993 • 1,727 citations

Integrins: Emerging Paradigms of Signal Transduction

1995 • 1,591 citations

Actin-Based Cell Motility and Cell Locomotion

1996 • 1,536 citations

Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly.

1992 • 1,330 citations

Morphology and growth, tumorigenicity, and cytogenetics of human neuroblastoma cells in continuous culture.

1973 • 1,284 citations

Cellular tensegrity: defining new rules of biological design that govern the cytoskeleton

1993 • 1,124 citations

On the Crawling of Animal Cells

1993 • 1,020 citations

The locomotion of fibroblasts in culture

1971 • 955 citations

Contact and adhesive specificities in the associations, migrations, and targeting of cells and axons

1992 • 895 citations

Plasticity of the Differentiated State

1985 • 839 citations

Cellular Adhesiveness and Extracellular Substrata

1978 • 829 citations

Small GTP-Binding Proteins and the Regulation of the Actin Cytoskeleton

1994 • 822 citations

A 130K protein from chicken gizzard: Its localization at the termini of microfilament bundles in cultured chicken cells

1979 • 794 citations

Cell-to-substrate contacts in living fibroblasts: an interference reflexion study with an evaluation of the technique

1976 • 705 citations

Characterization of a newly derived human sarcoma cell line (HT-1080)

1974 • 681 citations

Diversity of function is inherent in matricellular proteins: an appraisal of thrombospondin 1.

1995 • 673 citations

α-Actinin: Immunofluorescent localization of a muscle structural protein in nonmuscle cells

1975 • 599 citations

Properties of a clonal muscle cell line from rat heart

1976 • 572 citations

Adhesion in cell migration

1995 • 520 citations

Cell attachment to thrombospondin: the role of ARG-GLY-ASP, calcium, and integrin receptors.

1988 • 481 citations

The Molecular Architecture of Focal Adhesions

1995 • 479 citations

Rous sarcoma virus-transformed fibroblasts adhere primarily at discrete protrusions of the ventral membrane called podosomes

1985 • 426 citations

Cell to substratum contacts of chick fibroblasts and their relation to the microfilament system. a correlated interference-reflexion and high-voltage electron-microscope study

1978 • 409 citations

GTPase cascades choreographing cellular behavior: Movement, morphogenesis, and more

1995 • 394 citations

The locomotion of fibroblasts in culture I. Movements of the leading edge

1970 • 389 citations

Characterization of two putative smooth muscle cell lines from rat thoracic aorta

1976 • 375 citations

Formation of cell-to-substrate contacts during fibroblast motility: An interference-reflexion study

1980 • 307 citations

Cell surface heparan sulfate mediates some adhesive responses to glycosaminoglycan-binding matrices, including fibronectin.

1983 • 281 citations

Tropomyosin antibody: the specific localization of tropomyosin in nonmuscle cells.

1975 • 280 citations

The behaviour of fibroblasts migrating from chick heart explants: changes in adhesion, locomotion and growth, and in the distribution of actomyosin and fibronectin

1979 • 244 citations

Functional properties of non-muscle tropomyosin isoforms

1994 • 244 citations

Transmembrane molecular assemblies in cell-extracellular matrix interactions

1991 • 244 citations

The properdin-like type I repeats of human thrombospondin contain a cell attachment site.

1991 • 238 citations

Microvilli and blebs as sources of reserve surface membrane during cell spreading

1976 • 232 citations

Platelet-derived growth factor and heparin-like glycosaminoglycans regulate thrombospondin synthesis and deposition in the matrix by smooth muscle cells.

1985 • 232 citations

Cell surface distribution of fibronectin and vitronectin receptors depends on substrate composition and extracellular matrix accumulation.

1988 • 228 citations

The riddle of morphogenesis: A question of solution chemistry or molecular cell engineering?

1993 • 219 citations

Thrombospondin modulates alpha v beta 3 function through integrin-associated protein.

1996 • 217 citations

Platelet thrombospondin mediates attachment and spreading of human melanoma cells.

1987 • 196 citations

Regulation of chondroitin sulfate synthesis. Effect of beta-xylosides on synthesis of chondroitin sulfate proteoglycan, chondroitin sulfate chains, and core protein.

1977 • 189 citations

beta-Catenin associates with the actin-bundling protein fascin in a noncadherin complex.

1996 • 172 citations

Thrombospondins

1991 • 169 citations

Integrins in point contacts mediate cell spreading: factors that regulate integrin accumulation in point contacts vs. focal contacts.

1993 • 165 citations

Fascins, a family of actin bundling proteins

1995 • 160 citations

Tyrosine phosphorylation of membrane proteins mediates cellular invasion by transformed cells.

1992 • 136 citations

Cell locomotion: New research tests old ldeas on membrane and cytoskeletal flow

1991 • 133 citations

Cellular invasion into matrix beads: Localization of fa integrins and fibronectin to the invadopodia

1991 • 131 citations

Phosphorylation of Human Fascin Inhibits Its Actin Binding and Bundling Activities

1996 • 129 citations

Formation of stable microspikes containing actin and the 55 kDa actin bundling protein, fascin, is a consequence of cell adhesion to thrombospondin-1: implications for the anti-adhesive activities of thrombospondin-1

1995 • 128 citations

Intracellular localization of the 55-kD actin-bundling protein in cultured cells: spatial relationships with actin, alpha-actinin, tropomyosin, and fimbrin.

1986 • 128 citations

Actin crosslinking proteins at the leading edge

1994 • 128 citations

Binding and degradation of platelet thrombospondin by cultured fibroblasts.

1984 • 126 citations

Purification and characterization of an F-actin-bundling 55-kilodalton protein from HeLa cells.

1985 • 124 citations

Substratum contacts and cytoskeletal reorganization of BALB/c 3T3 cells on a cell-binding fragment and heparin-binding fragments of plasma fibronectin

1986 • 111 citations

Observations on microextensions from the surface of isolated vertebrate cells

1963 • 110 citations

Synapse Formation Between Two Clonal Cell Lines

1977 • 110 citations

Talin and vinculin play distinct roles in filopodial motility in the neuronal growth cone.

1996 • 108 citations

Characterization of neural cell adhesion sites: point contacts are the sites of interaction between integrins and the cytoskeleton in PC12 cells

1994 • 107 citations

Epstein-Barr virus infection induces expression in B lymphocytes of a novel gene encoding an evolutionarily conserved 55-kilodalton actin-bundling protein

1994 • 105 citations

Rapid cellular translocation is related to close contacts formed between various cultured cells and their substrata

1982 • 103 citations

Dynamic cytoskeleton-integrin associations induced by cell binding to immobilized fibronectin.

1989 • 101 citations

Cellular attachment to thrombospondin. Cooperative interactions between receptor systems

1991 • 99 citations

Thrombospondin promotes chemotaxis and haptotaxis of human peripheral blood monocytes.

1994 • 99 citations

The Thrombospondin Gene Family

1995 • 92 citations

Vinculin-deficient PC12 cell lines extend unstable lamellipodia and filopodia and have a reduced rate of neurite outgrowth.

1994 • 90 citations

Diverse mechanisms for cell attachment to platelet thrombospondin

1993 • 90 citations

Integrin alpha 3 beta 1 participates in the phagocytosis of extracellular matrix molecules by human breast cancer cells.

1996 • 89 citations

Biological activities of peptides and peptide analogues derived from common sequences present in thrombospondin, properdin, and malarial proteins.

1992 • 87 citations

Cell-type specific adhesive interactions of skeletal myoblasts with thrombospondin-1.

1994 • 85 citations

Fibroblast adhesion to RGDS shows novel features compared with fibronectin.

1987 • 85 citations

Narrow linear strips of adhesive substratum are powerful inducers of both growth and total focal contact area

1990 • 79 citations

Cloning and Expression of a Murine Fascin Homolog from Mouse Brain

1995 • 74 citations

Close and focal contact adhesions of fibroblasts to a fibronectin-containing matrix.

1985 • 67 citations

Thrombospondin is synthesized and secreted by human osteoblasts and osteosarcoma cells

1989 • 60 citations

Properties of recombinant mouse thrombospondin 2 expressed in Spodoptera cells.

1994 • 58 citations

Motility of Vinculin-Deficient F9 Embryonic Carcinoma Cells Analyzed by Video, Laser Confocal, and Reflection Interference Contrast Microscopy

1995 • 55 citations

Tension in the culture dish: Microfilament organization and migratory behavior of quail neural crest cells

1985 • 49 citations

α5 Integrin Is a Critical Component of Adhesion Plaques in Myogenesis

1993 • 48 citations

Expression of chicken vinculin complements the adhesion-defective phenotype of a mutant mouse F9 embryonal carcinoma cell.

1993 • 46 citations

NG2 proteoglycan and the actin-binding protein fascin define separate populations of actin-containing filopodia and lamellipodia during cell spreading and migration.

1996 • 42 citations

A vertebrate homolog of the actin-bundling protein fascin

1994 • 39 citations

Modulation of actin-bundling activity of 55-kDa protein by multiple isoforms of tropomyosin.

1986 • 31 citations

[5] Laminins

1994 • 30 citations

Neutrophil thrombospondin receptors are linked to GTP-binding proteins

1996 • 18 citations