PrP Genotype and Agent Effects in Scrapie: Change In Allelic Interaction With Different Isolates of Agent in Sheep, a Natural Host of Scrapie

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

1985 • 9,128 citations

A general method for isolation of high molecular weight DNA from eukaryotes

1976 • 2,827 citations

Mice devoid of PrP are resistant to scrapie

1993 • 2,058 citations

A cellular gene encodes scrapie PrP 27-30 protein

1985 • 1,494 citations

Homozygous prion protein genotype predisposes to sporadic Creutzfeldt–Jakob disease

1991 • 871 citations

Fatal Familial Insomnia and Familial Creutzfeldt-Jakob Disease: Disease Phenotype Determined by a DNA Polymorphism

1992 • 680 citations

Genetic predisposition to iatrogenic Creutzfeldt-Jakob disease

1991 • 543 citations

Distinct prion proteins in short and long scrapie incubation period mice

1987 • 482 citations

"Friendly fire" in medicine: hormones, homografts, and Creutzfeldt-Jakob disease

1992 • 354 citations

Propagation of prions with artificial properties in transgenic mice expressing chimeric PrP genes

1993 • 331 citations

Two alleles of a neural protein gene linked to scrapie in sheep.

1990 • 301 citations

Transmission of bovine spongiform encephalopathy to sheep and goats

1993 • 296 citations

Fibrils from brains of cows with new cattle disease contain scrapie-associated protein

1988 • 233 citations

Transmission of bovine spongiform encephalopathy and scrapie to mice

1992 • 199 citations

Different Forms of the Bovine PrP Gene have Five or Six Copies of a Short, G-C-rich Element within the Protein-coding Exon

1991 • 197 citations

PrP Polymorphisms Associated with Natural Scrapie Discovered by Denaturing Gradient Gel Electrophoresis

1993 • 174 citations

Genetic Aspects of Unconventional Virus Infections: The Basis of the Virino Hypothesis

2007 • 164 citations

Different scrapie-associated fibril proteins (PrP) are encoded by lines of sheep selected for different alleles of the Sip gene

1991 • 142 citations

The unusual properties of CH1641, a sheep-passaged isolate of scrapie

1988 • 123 citations

Swaledale sheep affected by natural scrapie differ significantly in PrP genotype frequencies from healthy sheep and those selected for reduced incidence of scrapie

1993 • 122 citations

Some factors controlling the incidence of scrapie in Cheviot sheep injected with a Cheviot-passaged scrapie agent

1968 • 80 citations

The normal Huntington disease (HD) allele, or a closely linked gene, influences age at onset of HD.

1993 • 58 citations

The phenotypic expression of different mutations in transmissible human spongiform encephalopathy.

1992 • 49 citations

Polymorphisms of a scrapie-associated fibril protein (PrP) gene and their association with susceptibility to experimentally induced scrapie in Cheviot sheep in the United States

1992 • 45 citations

Valine homozygous 129 PrP genotype in a French growth‐hormone‐related Creutzfeldt‐Jakob disease patient

1993 • 7 citations