Considerations for the treatment of secondary hyperparathyroidism in renal failure.

Decreased 1,25-dihydroxyvitamin D3 receptor density is associated with a more severe form of parathyroid hyperplasia in chronic uremic patients.

1993 • 594 citations

Depressed expression of calcium receptor in parathyroid gland tissue of patients with hyperparathyroidism

1997 • 494 citations

Four-Parameter Model of the Sigmoidal Relationship between Parathyroid Hormone Release and Extracellular Calcium Concentration in Normal and Abnormal Parathyroid Tissue*

1983 • 449 citations

Monoclonality of parathyroid tumors in chronic renal failure and in primary parathyroid hyperplasia.

1995 • 411 citations

Bone disease in predialysis, hemodialysis, and CAPD patients: Evidence of a better bone response to PTH

1995 • 333 citations

Evidence for abnormal calcium homeostasis in patients with adynamic bone disease

1994 • 330 citations

Direct effect of phosphorus on PTH secretion from whole rat parathyroid glands in vitro

1996 • 326 citations

Effect of alfacalcidol on natural course of renal bone disease in mild to moderate renal failure

1995 • 313 citations

Intact parathyroid hormone overestimates the presence and severity of parathyroid-mediated osseous abnormalities in uremia.

1992 • 292 citations

1,25(OH)2 vitamin D3 inhibits parathyroid cell proliferation in experimental uremia

1989 • 269 citations

Prospective trial of pulse oral versus intravenous calcitriol treatment of hyperparathyroidism in ESRD

1994 • 255 citations

Are we mismanaging calcium and phosphate metabolism in renal failure?

1997 • 175 citations

Serial Evaluation of Parathyroid Size by Ultrasonography Is Another Useful Marker for the Long-Term Prognosis of Calcitriol Pulse Therapy in Chronic Dialysis Patients

1994 • 171 citations

1,25(OH)2D3 administration in moderate renal failure: A prospective double-blind trial

1989 • 163 citations

Calcium Metabolism in Early Chronic Renal Failure: Implications for the Pathogenesis of Hyperparathyroidism

1991 • 162 citations

Inhibition of calcitriol receptor binding to vitamin D response elements by uremic toxins.

1995 • 141 citations

Low Dose CalcitriolVersusPlacebo in Patients with Predialysis Chronic Renal Failure*

1988 • 122 citations

Calcium kinetics and the long-term effects of lowering dialysate calcium concentration

1993 • 121 citations

The effect of long-term intravenous calcitriol administration on parathyroid function in hemodialysis patients.

1991 • 105 citations

Low-dose calcitriol prevents the rise in 1,84 iPTH without affecting serum calcium and phosphate in patients with moderate renal failure (prospective placebo-controlled multicentre trial)

1995 • 85 citations

Pathologic study of parathyroid glands in tertiary hyperparathyroidism

1985 • 81 citations

A deficit of calcitriol synthesis may not be the initial factor in the pathogenesis of secondary hyperparathyroidism

1996 • 80 citations

Pharmacokinetics and efficacy of pulse oral versus intravenous calcitriol in hemodialysis patients.

1996 • 77 citations

Comparison of intermittent oral and intravenous calcitriol in hemodialysis patients with secondary hyperparathyroidism.

1993 • 75 citations

Factors in the development of secondary hyperparathyroidism during graded renal failure in the rat

1994 • 74 citations

Parathyroid cell proliferation in the rat: effect of age and of phosphate administration and recovery.

1996 • 71 citations

Intermittent versus continuous administration of 1,25-dihydroxyvitamin D3 in experimental renal hyperparathyroidism

1993 • 70 citations

Evidence of healing of secondary hyperparathyroidism in chronically hemodialyzed uremic patients treated with long-term intravenous calcitriol

1994 • 69 citations

Low-calcium dialysate stimulates parathormone secretion and its long-term use worsens secondary hyperparathyroidism.

1995 • 66 citations

Comparison of Intermittent and Continuous Oral Administration of Calcitriol in Dialysis Patients: A Randomized Prospective Trial

1994 • 63 citations

The Use of 1,25-Dihydroxyvitamin D in Early Renal Failure

1992 • 59 citations

Use of oral and parenteral calcitriol in the treatment of renal osteodystrophy.

1990 • 58 citations

Optimum Dialysate Calcium Concentration During Maintenance Hemodialysis

1976 • 47 citations

Effect of phosphate on the parathyroid gland: direct and indirect?

1996 • 41 citations

Relative effects of PTH and dietary phosphorus on calcitriol production in normal and azotemic rats

1996 • 38 citations

The dilemma of parathyroidectomy in chronic renal failure

1994 • 36 citations

Evidence for Both Abnormal Set Point of PTH Stimulation by Calcium and Adaptation to Serum Calcium in Hemodialysis Patients with Hyperparathyroidism

1997 • 36 citations

Differences in the dynamics of parathyroid hormone secretion in hemodialysis patients with marked secondary hyperparathyroidism.

1995 • 29 citations

Effect of the mode of calcitriol administration on PTH-ionized calcium relationship in uraemic patients with secondary hyperparathyroidism

1995 • 29 citations

II. Early parathyroidectomy should be considered as the first choice

1994 • 26 citations

Identification of risk factors on secondary hyperparathyroidism undergoing long-term haemodialysis with vitamin D3

1994 • 25 citations

Calcitriol in the Management of Renal Osteodystrophy

1996 • 14 citations

Serum ionized calcium, parathyroid hormone and phosphate in uremic patients during and between hemodialysis.

1993 • 8 citations

The prevention of secondary hyperparathyroidism

1993 • 3 citations