PPARδ regulates glucose metabolism and insulin sensitivity

THE GLUCOSE FATTY-ACID CYCLE ITS ROLE IN INSULIN SENSITIVITY AND THE METABOLIC DISTURBANCES OF DIABETES MELLITUS

1963 • 5,061 citations

An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor γ (PPARγ)

1995 • 3,603 citations

Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism*

1999 • 2,880 citations

Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ

1997 • 2,105 citations

Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ

1997 • 2,100 citations

Nuclear Receptors and Lipid Physiology: Opening the X-Files

2001 • 2,040 citations

PPARγ Is Required for the Differentiation of Adipose Tissue In Vivo and In Vitro

1999 • 1,963 citations

PPARγ Is Required for Placental, Cardiac, and Adipose Tissue Development

1999 • 1,904 citations

Role of LXRs in control of lipogenesis

2000 • 1,623 citations

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ

2000 • 1,619 citations

Peroxisome proliferator–activated receptor α mediates the adaptive response to fasting

1999 • 1,589 citations

PPARγ Mediates High-Fat Diet–Induced Adipocyte Hypertrophy and Insulin Resistance

1999 • 1,339 citations

Peroxisome-Proliferator-Activated Receptor δ Activates Fat Metabolism to Prevent Obesity

2003 • 1,260 citations

Fatty Acids, Eicosanoids, and Hypolipidemic Agents Identified as Ligands of Peroxisome Proliferator-Activated Receptors by Coactivator-Dependent Receptor Ligand Assay

1997 • 1,158 citations

A selective peroxisome proliferator-activated receptor δ agonist promotes reverse cholesterol transport

2001 • 1,050 citations

Regulation of Muscle Fiber Type and Running Endurance by PPARδ

2004 • 1,050 citations

Adipose-specific peroxisome proliferator-activated receptor γ knockout causes insulin resistance in fat and liver but not in muscle

2003 • 944 citations

A critical role for the peroxisome proliferator-activated receptor α (PPARα) in the cellular fasting response: The PPARα-null mouse as a model of fatty acid oxidation disorders

1999 • 931 citations

Minireview: Lipid Metabolism, Metabolic Diseases, and Peroxisome Proliferator-Activated Receptors

2003 • 864 citations

Activation of peroxisome proliferator-activated receptor δ induces fatty acid β-oxidation in skeletal muscle and attenuates metabolic syndrome

2003 • 811 citations

Growth, Adipose, Brain, and Skin Alterations Resulting from Targeted Disruption of the Mouse Peroxisome Proliferator-Activated Receptor β(δ)

2000 • 641 citations

Effects of peroxisome proliferator-activated receptor δ on placentation, adiposity, and colorectal cancer

2001 • 591 citations

Transcriptional Repression of Atherogenic Inflammation: Modulation by PPARδ

2003 • 580 citations

Muscle-specific Pparg deletion causes insulin resistance

2003 • 487 citations

PPARγ coactivator 1β/ERR ligand 1 is an ERR protein ligand, whose expression induces a high-energy expenditure and antagonizes obesity

2003 • 346 citations

Activation of PPARδ alters lipid metabolism in db/db mice

2000 • 313 citations

Syndrome X: 6 years later.

1994 • 254 citations

¹³ C NMR studies of gluconeogenesis in rat liver cells: Utilization of labeled glycerol by cells from euthyroid and hyperthyroid rats

1979 • 115 citations

A comparison of 13C nuclear magnetic resonance and 14C tracer studies of hepatic metabolism.

1981 • 99 citations

Peroxisome Proliferator-activated Receptor β/δ Regulates Very Low Density Lipoprotein Production and Catabolism in Mice on a Western Diet

2004 • 97 citations

Enhancing hepatic glycolysis reduces obesity: Differential effects on lipogenesis depend on site of glycolytic modulation

2005 • 96 citations

Acetyl-CoA Carboxylase β Gene Is Regulated by Sterol Regulatory Element-binding Protein-1 in Liver

2003 • 84 citations

Software and methods for oligonucleotide and cDNA array data analysis

2002 • 46 citations

Computational comparison of two mouse draft genomes and the human golden path

2002 • 38 citations

Acetyl-CoA carboxylase beta gene is regulated by sterol regulatory element-binding protein-1 in liver

2003 • 17 citations

Altered Hepatic and Muscle Substrate Utilization Provoked by GLUT4 Ablation

2005 • 16 citations