Oligodendrocyte development and differentiation in the rumpshaker mutation

Monoclonal antibodies (O1 to O4) to oligodendrocyte cell surfaces: An immunocytological study in the central nervous system

1981 • 1,131 citations

Development of oligodendrocytes and Schwann cells studied with a monoclonal antibody against galactocerebroside.

1982 • 842 citations

Glial Cell Diversification in the Rat Optic Nerve

1989 • 725 citations

Multiple and novel specificities of monoclonal antibodies O1, O4, and R‐mAb used in the analysis of oligodendrocyte development

1989 • 422 citations

Emergence of three myelin proteins in oligodendrocytes cultured without neurons.

1986 • 333 citations

Chromosomal mapping of mouse myelin basic protein gene and structure and transcription of the partially deleted gene in shiverer mutant mice

1985 • 331 citations

Splice site selection in the proteolipid protein (PLP) gene transcript and primary structure of the DM-20 protein of central nervous system myelin.

1987 • 300 citations

A leucine-to-proline mutation in the putative first transmembrane domain of the 22-kDa peripheral myelin protein in the trembler-J mouse.

1992 • 286 citations

Development of macroglial cells in rat cerebellum II. An in situ immunohistochemical study of oligodendroglial lineage from precursor to mature myelinating cell

1988 • 255 citations

Proliferation and differentiation potential of rat forebrain oligodendroglial progenitors both in vitro and in vivo

1991 • 249 citations

Cellular and molecular aspects of myelin protein gene expression

1988 • 224 citations

Oligodendroglial cell death in jimpy mice: an explanation for the myelin deficit

1986 • 218 citations

Uncoupling of hypomyelination and glial cell death by a mutation in the proteolipid protein gene

1992 • 212 citations

Proligodendroblast Antigen (POA), a Developmental Antigen Expressed by A007/O4‐Positive Oligodendrocyte Progenitors Prior to the Appearance of Sulfatide and Galactocerebroside

1992 • 185 citations

DM‐20 mRNA Is Expressed During the Embryonic Development of the Nervous System of the Mouse

1992 • 173 citations

Myelin deficit in the Jimpy mouse may be due to cellular abnormalities in astroglia

1976 • 160 citations

The timely expression of myelin basic protein gene in cultured rat brain oligodendrocytes is independent of continuous neuronal influences

1985 • 158 citations

Development of macroglial cells in rat cerebellum. I. Use of antibodies to follow earlyin vivo development and migration of oligodendrocytes

1988 • 147 citations

Abnormal compact myelin in the myelin-deficient rat: absence of proteolipid protein correlates with a defect in the intraperiod line.

1987 • 142 citations

Cell type specificity of a neural cell surface antigen recognized by the monoclonal antibody A2B5

1982 • 142 citations

Selective Expression of DM‐20, an Alternatively Spliced Myelin Proteolipid Protein Gene Product, in Developing Nervous System and in Nonglial Cells

1992 • 141 citations

Proliferation and differentiation of O4⁺ oligodendrocytes in postnatal rat cerebellum: Analysis in unfixed tissue slices using anti‐glycolipid antibodies

1992 • 139 citations

Myelin-deficient rat: a point mutation in exon III (A----C, Thr75----Pro) of the myelin proteolipid protein causes dysmyelination and oligodendrocyte death.

1989 • 129 citations

Development of transferrin‐positive oligodendrocytes in the rat central nervous system

1987 • 119 citations

A point mutation in the proteolipid protein gene of the ‘shaking pup’ interrupts oligodendrocyte development

1990 • 115 citations

Developmental Expression of the Myelin Proteolipid Protein and Basic Protein mRNAs in Normal and Dysmyelinating Mutant Mice

1987 • 112 citations

Rumpshaker mouse: A new X-linked mutation affecting myelination: Evidence for a defect in PLP expression

1990 • 96 citations

Novel stage in the oligodendrocyte lineage defined by reactivity of progenitors with R‐mAb prior to O1 anti‐galactocerebroside

1992 • 93 citations

Expression of Myelin Proteolipid Protein and Basic Protein in Normal and Dysmyelinating Mutant Mice

1986 • 93 citations

Myelination in the jimpy mouse in the absence of proteolipid protein

1989 • 90 citations

Gel electrophoresis studies of bovine brain white matter proteolipid and myelin proteins

1974 • 89 citations

Expression of galactocerebroside in developing normal and jimpy oligodendrocytesin situ

1988 • 85 citations

Myelin Proteolipid Protein Gene Expression in Jimpy and Jimpy^msdMice

1988 • 82 citations

Regulation of oligodendrocyte differentiation

1992 • 74 citations

Glial conditioned medium enables jimpy oligodendrocytes to express properties of normal oligodendrocytes: Production of myelin antigens and membranes

1988 • 65 citations

Death of Individual Oligodendrocytes in <i>Jimpy</i> Brain Precedes Expression of Proteolipid Protein

1990 • 60 citations

Myelin‐Deficient Rat: Analysis of Myelin Proteins

1986 • 58 citations

Cerebral endothelial cell infection by measles virus in subacute sclerosing panencephalitis: ultrastructural and in situ hybridization evidence

1991 • 56 citations

Rumpshaker: An X‐linked mutation causing hypomyelination: Developmental differences in myelination and glial cells between the optic nerve and spinal cord

1992 • 51 citations

A specific immunological probe for the major myelin proteolipid

1986 • 47 citations

Proteolipid proteins: structure and genetic expression in normal and myelin-deficient mutant mice.

1989 • 47 citations

Mutations in the Myelin Proteolipid Protein Gene Alter Oligodendrocyte Gene Expression in Jimpy and Jimpy^msd Mice

1991 • 46 citations

Developmental Study of Proteolipids in Bovine Brain: A Novel Proteolipid and DM‐20 Appear Before Proteolipid Protein (PLP) During Myelination

1990 • 44 citations

Transferrin: An early marker of oligodendrocytes in culture

1988 • 44 citations

Hyperplasia of oligodendrocytes in quaking mice

1975 • 43 citations

Dissection of the Phenotype and Genotype of the X‐Linked Myelin Mutants^a

1990 • 40 citations

Abnormal cell relationships in Jimpy mice: electron microscopic and immunocytochemical findings

1983 • 39 citations

Developmental expression of major myelin protein genes in the CNS of X‐Linked hypomyelinating mutant rumpshaker

1992 • 36 citations

Developmental Expression of Myelin Protein Genes in Dysmyelinating Mutant Mice: Analysis by Nuclear Run‐Off Transcription Assay, In Situ Hybridization, and Immunohistochemistry

1991 • 36 citations

The DM20 Protein of Myelin: Intracellular and Surface Expression Patterns in Transfectants

1992 • 31 citations

Site-specific antibodies to rat myelin proteolipids directed against the C-terminal hexapeptide

1985 • 30 citations

Myelin basic protein is affected by reduced synthesis of myelin proteolipid protein in the jimpy mouse

1990 • 28 citations

Molecular Genetics of X‐Linked Mutants

1990 • 26 citations

Purification and characterization of minor brain proteolipids: use of fast atom bombardment — mass spectrometry for peptide sequencing

1986 • 25 citations

Gene Expression in the <i>Jimpy </i>Mutant: Evidence for Fewer Oligodendrocytes Expressing Myelin Protein Genes and Impaired Translocation of Myelin Basic Protein mRNA

1990 • 25 citations

Disproportional Expression of Proteolipid Protein and DM-20 in the X-Linked, Dysmyelinating Shaking Pup Mutant

1987 • 24 citations

Oligodendrocytes of the jimpy phenotype can be partially restored by environmental factors in vivo

1991 • 22 citations

Postnatal development of rat peripheral nerves: an immunohistochemical study of membrane lipids common to non-myelin forming Schwann cells, myelin forming Schwann cells and oligodendrocytes

1987 • 22 citations

Differences in Levels of Neuroglial Cell Death in Jimpy Male Mice and Carrier Females

1990 • 17 citations

Expression of the Jimpy Phenotype in Relation to Proteolipid Protein Appearance

1990 • 16 citations

Rumpshaker: an X‐linked mutation affecting CNS myelination. A study of the female heterozygote

1991 • 15 citations

Stage Specific Antigens on Oligodendrocyte Cell Surfaces

1984 • 13 citations

The <i>Myelin-Deficient</i>Rat Mutant: Partial Recovery of Oligodendrocyte Maturation in vitro

1990 • 12 citations

The Biochemistry of Myelin in X‐Linked Mutants

1990 • 8 citations

Regulation of Oligodendrocyte Progenitor Development: Antibody-Perturbation Studies

1990 • 7 citations

Rumpshaker Mouse A Probable Mutation of the PLP Gene^a

1990 • 6 citations